P12131 (NDHH_MARPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
NAD(P)H-quinone oxidoreductase subunit H, chloroplastic
EC=1.6.5.-

Alternative name(s):
NAD(P)H dehydrogenase subunit H
NADH-plastoquinone oxidoreductase 49 kDa subunit
NADH-plastoquinone oxidoreductase subunit H

Gene names

Name:

ndhH

Encoded on

Plastid; Chloroplast

Organism

Marchantia polymorpha (Liverwort) (Marchantia aquatica)

Taxonomic identifier

3197 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Marchantiophyta › Marchantiopsida › Marchantiidae › Marchantiales › Marchantiaceae › Marchantia

Protein attributes

Sequence length	392 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	NDH shuttles electrons from NAD(P)H:plastoquinone, via FMN and iron-sulfur (Fe-S) centers, to quinones in the photosynthetic chain and possibly in a chloroplast respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient By similarity. HAMAP MF_01358
Catalytic activity	NAD(P)H + plastoquinone = NAD(P)+ + plastoquinol. HAMAP MF_01358
Subunit structure	NDH is composed of at least 16 different subunits, 5 of which are encoded in the nucleus By similarity.
Subcellular location	Plastid › chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side By similarity HAMAP MF_01358.
Sequence similarities	Belongs to the complex I 49 kDa subunit family.

Ontologies

Keywords
Biological process	Transport
Cellular component	Chloroplast Membrane Plastid Thylakoid
Ligand	NAD NADP Plastoquinone
Molecular function	Oxidoreductase
PTM	Quinone
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chloroplast thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	NAD binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on NADH or NADPH Inferred from electronic annotation. Source: InterPro quinone binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 392	392	NAD(P)H-quinone oxidoreductase subunit H, chloroplastic HAMAP MF_01358		PRO_0000118603

Sequences

	Sequence		Length	Mass (Da)
	P12131 [UniParc]. Last modified October 1, 1989. Version 1. Checksum: E3512B9798935278	FASTA	392	45,372
	10 20 30 40 50 60 MMILTKNKPM IVSMGPHHPS MHGVLRLIVT LDGEDVLDCE PVLGYLHRGM EKIAENRTIV 70 80 90 100 110 120 QYLPYVTRWD YLATMFTEAI TVNAPEKLTN IQVPKRASYI RIIMLELSRI ASHLLWLGPF 130 140 150 160 170 180 MADIGAQTPF FYIFREREMI YDLFESATGM RMMHNYFRIG GVAVDLPYGW IDKCLDFCDY 190 200 210 220 230 240 FLPKINEYER LITNNPIFLK RVEGIGTVTR EEAINWGLSG PMLRASGVQW DLRKVDHYEC 250 260 270 280 290 300 YDELDWKIQW QKEGDSLARY LVRIGEMKES VKIIQQALKA IPGGPFENLE ARRLNQGKNS 310 320 330 340 350 360 EWNLFEYQFI SKKPSPTFKL PKQEHYVRVE APKGELGIFL IGDDSVFPWR LKIRSPGFIN 370 380 390 LQILPQLVKG MKLADIMTIL GSIDIIMGEV DR

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Chloroplast gene organization deduced from complete sequence of liverwort Marchantia polymorpha chloroplast DNA." Ohyama K., Fukuzawa H., Kohchi T., Shirai H., Sano T., Sano S., Umesono K., Shiki Y., Takeuchi M., Chang Z., Aota S., Inokuchi H., Ozeki H. Nature 322:572-574(1986) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"Structure and organization of Marchantia polymorpha chloroplast genome. IV. Inverted repeat and small single copy regions." Kohchi T., Shirai H., Fukuzawa H., Sano T., Komano T., Umesono K., Inokuchi H., Ozeki H., Ohyama K. J. Mol. Biol. 203:353-372(1988) [PubMed: 3199437] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	X04465 Genomic DNA. Translation: CAA28140.1.
PIR	A05025. S01522.
RefSeq	NP_039354.1. NC_001319.1.
3D structure databases
ProteinModelPortal	P12131.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2702616.
Phylogenomic databases
ProtClustDB	CHL00017.
Family and domain databases
HAMAP	MF_01358. NDH1_NuoD. [Tree]
InterPro	IPR010219. NADH_DH_1_suD. IPR001135. NADH_Q_OxRdtase_suD. IPR014029. NADH_UbQ_OxRdtase_49kDa_CS. IPR022885. NDH1_su_D/H. [Graphical view]
Pfam	PF00346. Complex1_49kDa. 1 hit. [Graphical view]
TIGRFAMs	TIGR01962. NuoD. 1 hit.
PROSITE	PS00535. COMPLEX1_49K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NDHH_MARPO

Accession

Primary (citable) accession number: P12131

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
Last sequence update:	October 1, 1989
Last modified:	September 21, 2011
This is version 85 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program