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P12011 (GNTK_BACSU) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 98. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Gluconokinase
EC=2.7.1.12
Alternative name(s):
Gluconate kinase
Gene names
Name:gntK
Ordered Locus Names:BSU40060
OrganismBacillus subtilis (strain 168) [Reference proteome] [HAMAP]
Taxonomic identifier224308 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus ›

Protein attributes

Sequence length513 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + D-gluconate = ADP + 6-phospho-D-gluconate.

Enzyme regulation

Catabolite repression by gluconate.

Pathway

Carbohydrate acid metabolism; D-gluconate degradation.

Sequence similarities

Belongs to the FGGY kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 513513Gluconokinase
PRO_0000059544

Regions

Nucleotide binding412 – 4165ATP By similarity

Sites

Binding site161ATP By similarity
Binding site2611ATP By similarity
Binding site3001ATP; via carbonyl oxygen By similarity

Sequences

Sequence LengthMass (Da)Tools
P12011 [UniParc].

Last modified October 1, 1989. Version 1.
Checksum: 351D44064C7AC3ED

FASTA51357,169
        10         20         30         40         50         60 
MTSYMLGIDI GTTSTKAVLF SENGDVVQKE SIGYPLYTPD ISTAEQNPEE IFQAVIHTTA 

        70         80         90        100        110        120 
RITKQHPEKR ISFISFSSAM HSVIAIDEND KPLTPCITWA DNRSEGWAHK IKEELNGHEV 

       130        140        150        160        170        180 
YKRTGTPIHP MAPLSKIAWI TNERKEIASK AKKYIGIKEY IFKQLFNEYV IDYSLASATG 

       190        200        210        220        230        240 
MMNLKGLDWD EEALRIAGIT PDHLSKLVPT TEIFQHCSPE IAIQMGIDPE TPFVIGASDG 

       250        260        270        280        290        300 
VLSNLGVNAI KKGEIAVTIG TSGAIRTIID KPQTDEKGRI FCYALTDKHW VIGGPVNNGG 

       310        320        330        340        350        360 
IVLRWIRDEF ASSEIETATR LGIDPYDVLT KIAQRVRPGS DGLLFHPYLA GERAPLWNPD 

       370        380        390        400        410        420 
VRGSFFGLTM SHKKEHMIRA ALEGVIYNLY TVFLALTECM DGPVTRIQAT GGFARSEVWR 

       430        440        450        460        470        480 
QMMSDIFESE VVVPESYESS CLGACILGLY ATGKIDSFDA VSDMIGSTYR HTPIEDSAKE 

       490        500        510 
YRTLMPIFIN LSRLLENQYT QIADYQRGLI THK

« Hide

References

« Hide 'large scale' references
[1]"Organization and transcription of the gluconate operon, gnt, of Bacillus subtilis."
Fujita Y., Fujita T., Miwa Y., Nihashi J., Aratani Y.
J. Biol. Chem. 261:13744-13753(1986) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Cloning and sequencing of a 36-kb region of the Bacillus subtilis genome between the gnt and iol operons."
Yoshida K., Seki S., Fujimura M., Miwa Y., Fujita Y.
DNA Res. 2:61-69(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168 / BGSC1A1.
[3]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		J02584 Genomic DNA. Translation: AAA56925.1.
AB005554 Genomic DNA. Translation: BAA21578.1.
AL009126 Genomic DNA. Translation: CAB16043.1.
PIRB26190.
RefSeqNP_391886.1. NC_000964.3.

3D structure databases

ProteinModelPortalP12011.
SMRP12011. Positions 1-503.
ModBaseSearch...

Protein-protein interaction databases

STRING224308.BSU40060.

Proteomic databases

PaxDbP12011.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB16043; CAB16043; BSU40060.
GeneID937713.
KEGGbsu:BSU40060.
PATRIC18980082. VBIBacSub10457_4203.

Organism-specific databases

GenoListBSU40060. [Micado]

Phylogenomic databases

eggNOGCOG1070.
HOGENOMHOG000222139.
KOK00851.
OMAFINLSRA.
ProtClustDBCLSK561418.

Enzyme and pathway databases

BioCycBSUB:BSU40060-MONOMER.
UniPathwayUPA00792.

Family and domain databases

InterProIPR018485. Carb_kinase_FGGY_C.
IPR018483. Carb_kinase_FGGY_CS.
IPR018484. Carb_kinase_FGGY_N.
IPR006002. Gluconate_kinase.
[Graphical view]
PfamPF02782. FGGY_C. 1 hit.
PF00370. FGGY_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR01314. gntK_FGGY. 1 hit.
PROSITEPS00933. FGGY_KINASES_1. 1 hit.
PS00445. FGGY_KINASES_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGNTK_BACSU
AccessionPrimary (citable) accession number: P12011
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1989
Last modified: May 1, 2013
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents