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Protein

60S ribosomal protein L18

Gene

Rpl18

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of the large ribosomal subunit.By similarity

GO - Molecular functioni

GO - Biological processi

  • cytoplasmic translation Source: UniProtKB
  • liver regeneration Source: RGD
  • translation Source: GO_Central

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L18
Gene namesi
Name:Rpl18
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi621182 Rpl18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001327721 – 18860S ribosomal protein L18Add BLAST188

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Cross-linki119Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei130PhosphoserineCombined sources1
Modified residuei158PhosphothreonineBy similarity1
Cross-linki164Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

PaxDbiP12001
PRIDEiP12001

PTM databases

iPTMnetiP12001
PhosphoSitePlusiP12001

Expressioni

Gene expression databases

GenevisibleiP12001 RN

Interactioni

Subunit structurei

Component of the large ribosomal subunit.By similarity

Protein-protein interaction databases

BioGridi249638, 1 interactor
IntActiP12001, 3 interactors
STRINGi10116.ENSRNOP00000028555

Structurei

3D structure databases

ProteinModelPortaliP12001
SMRiP12001
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1714 Eukaryota
COG1727 LUCA
HOGENOMiHOG000213425
HOVERGENiHBG000875
InParanoidiP12001
KOiK02883
OrthoDBiEOG091G07WU
PhylomeDBiP12001
TreeFamiTF300202

Family and domain databases

InterProiView protein in InterPro
IPR036227 L18e/L15P_sf
IPR000039 Ribosomal_L18e
IPR021131 Ribosomal_L18e/L15P
IPR021132 Ribosomal_L18e_CS
PANTHERiPTHR10934 PTHR10934, 1 hit
PfamiView protein in Pfam
PF17135 Ribosomal_L18, 1 hit
SUPFAMiSSF52080 SSF52080, 1 hit
PROSITEiView protein in PROSITE
PS01106 RIBOSOMAL_L18E, 1 hit

Sequencei

Sequence statusi: Complete.

P12001-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVDIRHNKD RKVRRKEPKS QDIYLRLLVK LYRFLARRTN STFNQVVLKR
60 70 80 90 100
LFMSRTNRPP LSLSRMIRKM KLPGRENKTA VVVGTITDDV RILEVPKLKV
110 120 130 140 150
CALRVSSRAR SRILKAGGKI LTFDQLALES PKGRGTVLLS GPRKGREVYR
160 170 180
HFGKAPGTPH SHTKPYVRSK GRKFERARGR RASRGYKN
Length:188
Mass (Da):21,659
Last modified:January 23, 2007 - v2
Checksum:i4EA14D683038E40A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M20156 mRNA Translation: AAA42070.1
BC084727 mRNA Translation: AAH84727.1
PIRiA29906 R5RT81
RefSeqiNP_112364.1, NM_031102.2
UniGeneiRn.484

Genome annotation databases

GeneIDi81766
KEGGirno:81766
UCSCiRGD:621182 rat

Similar proteinsi

Entry informationi

Entry nameiRL18_RAT
AccessioniPrimary (citable) accession number: P12001
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 121 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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