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Protein

60S ribosomal protein L18

Gene

Rpl18

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • liver regeneration Source: RGD
  • translation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L18
Gene namesi
Name:Rpl18
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi621182. Rpl18.

Subcellular locationi

GO - Cellular componenti

  • cytosolic large ribosomal subunit Source: RGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001327722 – 18860S ribosomal protein L18Add BLAST187

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei130PhosphoserineCombined sources1
Modified residuei158PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP12001.
PRIDEiP12001.

PTM databases

iPTMnetiP12001.
PhosphoSitePlusiP12001.

Expressioni

Gene expression databases

BgeeiENSRNOG00000021035.
GenevisibleiP12001. RN.

Interactioni

Protein-protein interaction databases

BioGridi249638. 1 interactor.
IntActiP12001. 1 interactor.
MINTiMINT-4577059.
STRINGi10116.ENSRNOP00000028555.

Structurei

3D structure databases

ProteinModelPortaliP12001.
SMRiP12001.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L18e family.Curated

Phylogenomic databases

eggNOGiKOG1714. Eukaryota.
COG1727. LUCA.
HOGENOMiHOG000213425.
HOVERGENiHBG000875.
InParanoidiP12001.
KOiK02883.
OrthoDBiEOG091G07WU.
PhylomeDBiP12001.
TreeFamiTF300202.

Family and domain databases

InterProiIPR000039. Ribosomal_L18e.
IPR021131. Ribosomal_L18e/L15P.
IPR021132. Ribosomal_L18e_CS.
[Graphical view]
PANTHERiPTHR10934. PTHR10934. 1 hit.
PfamiPF17135. Ribosomal_L18. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
PROSITEiPS01106. RIBOSOMAL_L18E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P12001-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGVDIRHNKD RKVRRKEPKS QDIYLRLLVK LYRFLARRTN STFNQVVLKR
60 70 80 90 100
LFMSRTNRPP LSLSRMIRKM KLPGRENKTA VVVGTITDDV RILEVPKLKV
110 120 130 140 150
CALRVSSRAR SRILKAGGKI LTFDQLALES PKGRGTVLLS GPRKGREVYR
160 170 180
HFGKAPGTPH SHTKPYVRSK GRKFERARGR RASRGYKN
Length:188
Mass (Da):21,659
Last modified:January 23, 2007 - v2
Checksum:i4EA14D683038E40A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M20156 mRNA. Translation: AAA42070.1.
BC084727 mRNA. Translation: AAH84727.1.
PIRiA29906. R5RT81.
RefSeqiNP_112364.1. NM_031102.2.
UniGeneiRn.484.

Genome annotation databases

GeneIDi81766.
KEGGirno:81766.
UCSCiRGD:621182. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M20156 mRNA. Translation: AAA42070.1.
BC084727 mRNA. Translation: AAH84727.1.
PIRiA29906. R5RT81.
RefSeqiNP_112364.1. NM_031102.2.
UniGeneiRn.484.

3D structure databases

ProteinModelPortaliP12001.
SMRiP12001.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi249638. 1 interactor.
IntActiP12001. 1 interactor.
MINTiMINT-4577059.
STRINGi10116.ENSRNOP00000028555.

PTM databases

iPTMnetiP12001.
PhosphoSitePlusiP12001.

Proteomic databases

PaxDbiP12001.
PRIDEiP12001.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi81766.
KEGGirno:81766.
UCSCiRGD:621182. rat.

Organism-specific databases

CTDi6141.
RGDi621182. Rpl18.

Phylogenomic databases

eggNOGiKOG1714. Eukaryota.
COG1727. LUCA.
HOGENOMiHOG000213425.
HOVERGENiHBG000875.
InParanoidiP12001.
KOiK02883.
OrthoDBiEOG091G07WU.
PhylomeDBiP12001.
TreeFamiTF300202.

Miscellaneous databases

PROiP12001.

Gene expression databases

BgeeiENSRNOG00000021035.
GenevisibleiP12001. RN.

Family and domain databases

InterProiIPR000039. Ribosomal_L18e.
IPR021131. Ribosomal_L18e/L15P.
IPR021132. Ribosomal_L18e_CS.
[Graphical view]
PANTHERiPTHR10934. PTHR10934. 1 hit.
PfamiPF17135. Ribosomal_L18. 1 hit.
[Graphical view]
SUPFAMiSSF52080. SSF52080. 1 hit.
PROSITEiPS01106. RIBOSOMAL_L18E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRL18_RAT
AccessioniPrimary (citable) accession number: P12001
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.