Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cryptic beta-glucoside bgl operon antiterminator

Gene

bglG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Mediates the positive regulation of the beta-glucoside (bgl) operon by functioning as a transcriptional antiterminator. This is an RNA-binding protein that recognizes a specific sequence located just upstream of two termination sites within the operon.

GO - Molecular functioni

  • RNA binding Source: EcoCyc

GO - Biological processi

Keywordsi

Molecular functionActivator, RNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciEcoCyc:EG10116-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cryptic beta-glucoside bgl operon antiterminator
Gene namesi
Name:bglG
Synonyms:bglC
Ordered Locus Names:b3723, JW3701
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10116 bglG

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002042441 – 278Cryptic beta-glucoside bgl operon antiterminatorAdd BLAST278

Post-translational modificationi

Phosphorylated and inactivated by BglF (eII-bgl). The degree of phosphorylation is dependent on the presence or absence of beta-glucosides which act as inducers of the operon expression. Addition of inducer result in the rapid dephosphorylation of BglG.

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP11989
PRIDEiP11989

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi4262138, 6 interactors
DIPiDIP-9216N
IntActiP11989, 14 interactors
MINTiP11989
STRINGi316385.ECDH10B_3910

Structurei

3D structure databases

ProteinModelPortaliP11989
SMRiP11989
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini67 – 171PRD 1PROSITE-ProRule annotationAdd BLAST105
Domaini172 – 278PRD 2PROSITE-ProRule annotationAdd BLAST107

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG4105CID Bacteria
COG3711 LUCA
HOGENOMiHOG000223756
InParanoidiP11989
KOiK03488
OMAiYPDEYAI
PhylomeDBiP11989

Family and domain databases

Gene3Di2.30.24.10, 1 hit
InterProiView protein in InterPro
IPR004341 CAT_RNA-bd_dom
IPR036650 CAT_RNA-bd_dom_sf
IPR011608 PRD
IPR036634 PRD_sf
IPR001550 Transcrpt_antitermin_CS
PfamiView protein in Pfam
PF03123 CAT_RBD, 1 hit
PF00874 PRD, 2 hits
SMARTiView protein in SMART
SM01061 CAT_RBD, 1 hit
SUPFAMiSSF50151 SSF50151, 1 hit
SSF63520 SSF63520, 2 hits
PROSITEiView protein in PROSITE
PS00654 PRD_1, 1 hit
PS51372 PRD_2, 2 hits

Sequencei

Sequence statusi: Complete.

P11989-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNMQITKILN NNVVVVIDDQ QREKVVMGRG IGFQKRAGER INSSGIEKEY
60 70 80 90 100
ALSSHELNGR LSELLSHIPL EVMATCDRII SLAQERLGKL QDSIYISLTD
110 120 130 140 150
HCQFAIKRFQ QNVLLPNPLL WDIQRLYPKE FQLGEEALTI IDKRLGVQLP
160 170 180 190 200
KDEVGFIAMH LVSAQMSGNM EDVAGVTQLM REMLQLIKFQ FSLNYQEESL
210 220 230 240 250
SYQRLVTHLK FLSWRILEHA SINDSDESLQ QAVKQNYPQA WQCAERIAIF
260 270
IGLQYQRKIS PAEIMFLAIN IERVRKEH
Length:278
Mass (Da):32,097
Last modified:October 1, 1989 - v1
Checksum:i5ACF1A14BF438B4F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M16487 Genomic DNA Translation: AAA23509.1
L10328 Genomic DNA Translation: AAA62074.1
U00096 Genomic DNA Translation: AAC76746.1
AP009048 Genomic DNA Translation: BAE77565.1
M17098 Genomic DNA Translation: AAA23512.1
M15746 Genomic DNA Translation: AAA83836.1 Sequence problems.
PIRiB25977
RefSeqiNP_418179.1, NC_000913.3
WP_001295251.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC76746; AAC76746; b3723
BAE77565; BAE77565; BAE77565
GeneIDi948235
KEGGiecj:JW3701
eco:b3723
PATRICifig|1411691.4.peg.2978

Similar proteinsi

Entry informationi

Entry nameiBGLG_ECOLI
AccessioniPrimary (citable) accession number: P11989
Secondary accession number(s): Q2M841, Q47078
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1989
Last modified: March 28, 2018
This is version 149 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health