Reviewed,
UniProtKB/Swiss-Prot P11988 (BGLB_ECOLI)
Last modified
November 25, 2008.
Version 76.
History...
Clusters with 100%,
90%,
50% identity |
Documents (4) |
Third-party data |
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Names and origin
| Protein names | Recommended name: 6-phospho-beta-glucosidase bglB EC=3.2.1.86 | ||||
| Gene names |
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| Organism | Escherichia coli (strain K12) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 83333 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia |
Protein attributes
| Sequence length | 470 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Can hydrolyze salicin and arbutin. |
| Catalytic activity | 6-phospho-beta-D-glucosyl-(1,4)-D-glucose + H(2)O = D-glucose + D-glucose 6-phosphate. |
| Sequence similarities | Belongs to the glycosyl hydrolase 1 family. |
Ontologies
Keywords | |
|---|---|
| Molecular function | Glycosidase Hydrolase |
| Technical term | Complete proteome |
Gene Ontology (GO) | |
| Biological process | carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro |
| Molecular function | 6-phospho-beta-glucosidase activity Inferred from electronic annotation. Source: EC cation bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 470 | 470 | 6-phospho-beta-glucosidase bglB | PRO_0000063898 | |||||
Sites | |||||||||
| Active site | 172 | 1 | Proton donor Potential | ||||||
| Active site | 361 | 1 | Nucleophile By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 147 | 1 | D → G in AAA23511. Ref.1 | ||||||
| Sequence conflict | 449 – 451 | 3 | GWY → RMVC in AAA23511. Ref.1 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "Beta-glucoside (bgl) operon of Escherichia coli K-12: nucleotide sequence, genetic organization, and possible evolutionary relationship to regulatory components of two Bacillus subtilis genes." Schnetz K., Toloczyki C., Rak B. J. Bacteriol. 169:2579-2590(1987) [PubMed: 3034860] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12. |
| [2] | "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication." Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R. Genomics 16:551-561(1993) [PubMed: 7686882] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076. |
| [3] | "The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076. |
| [4] | "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911. |
| [5] | "Nucleotide sequence of bglC, the gene specifying enzymeIIbgl of the PEP:sugar phosphotransferase system in Escherichia coli K12, and overexpression of the gene product." Bramley H.F., Kornberg H.L. J. Gen. Microbiol. 133:563-573(1987) [PubMed: 3309161] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-19. Strain: K12. |
Cross-references
Sequence databases | |
|---|---|
| M16487 Genomic DNA. Translation: AAA23511.1. L10328 Genomic DNA. Translation: AAA62072.1. U00096 Genomic DNA. Translation: AAC76744.1. AP009048 Genomic DNA. Translation: BAE77567.1. M15746 Genomic DNA. Translation: AAA83838.1. | |
| PIR | B65175. |
| RefSeq | AP_004066.1. NP_418177.1. |
3D structure databases | |
| HSSP | HSSP built from PDB template 1GNX based on UniProtKB Q59976. |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 948234. |
| GenomeReviews | Gene locus b3721 in contig U00096_GR. Gene locus JW3699 in contig AP009048_GR. |
| KEGG | ecj:JW3699. eco:b3721. |
Organism-specific databases | |
| EchoBASE | EB0112. |
| EcoGene | EG10114. bglB. |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P11988. |
Enzyme and pathway databases | |
| BioCyc | EcoCyc:EG10114-MON. MetaCyc:EG10114-MON. |
Family and domain databases | |
| InterPro | IPR001360. Glyco_hydro_1. IPR013781. Glyco_hydro_sub_cat. [Graphical view] |
| Gene3D | G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit. |
| PANTHER | PTHR10353. Glyco_hydro_1. 1 hit. |
| Pfam | PF00232. Glyco_hydro_1. 1 hit. [Graphical view] |
| PRINTS | PR00131. GLHYDRLASE1. |
| PROSITE | PS00572. GLYCOSYL_HYDROL_F1_1. 1 hit. PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | BGLB_ECOLI | ||||||||
| Accession | Primary (citable) accession number: P11988 Secondary accession number(s): P78124, Q2M839 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| Escherichia coli Escherichia coli (strain K12): entries and cross-references to EcoGene |
| Glycosyl hydrolases Classification of glycosyl hydrolase families and list of entries |
| UniProtKB secondary accession numbers Index of UniProtKB secondary accession numbers |
| SIMILARITY comments Index of protein domains and families |

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