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P11977

- PGK_EMENI

UniProt

P11977 - PGK_EMENI

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Protein
Phosphoglycerate kinase
Gene
pgkA, pgk, AN1246
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei42 – 421Substrate By similarity
Binding sitei125 – 1251Substrate By similarity
Binding sitei173 – 1731Substrate By similarity
Binding sitei222 – 2221ATP By similarity
Binding sitei315 – 3151ATP; via carbonyl oxygen By similarity
Binding sitei346 – 3461ATP By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi375 – 3784ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: ASPGD

GO - Biological processi

  1. glycolytic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgkA
Synonyms:pgk
ORF Names:AN1246
OrganismiEmericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic identifieri227321 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000000560: Chromosome VIII

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. intracellular Source: ASPGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 421421Phosphoglycerate kinaseUniRule annotation
PRO_0000145880Add
BLAST

Proteomic databases

PRIDEiP11977.

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi162425.CADANIAP00001377.

Structurei

3D structure databases

ProteinModelPortaliP11977.
SMRiP11977. Positions 2-419.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate binding By similarity
Regioni66 – 694Substrate binding By similarity

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0126.
HOGENOMiHOG000227107.
KOiK00927.
OMAiFPVDYVT.
OrthoDBiEOG71K6D7.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P11977-1 [UniParc]FASTAAdd to Basket

« Hide

MSLTSKLSIT DVDLKDKRVL IRVDFNVPLD KNDNTTITNP QRIVGALPTI    50
KYAIDNGAKA VILMSHLGRP DGKKNPKYSL KPVVPKLKEL LGRDVIFTED 100
CVGPEVEETV NKASGGQVIL LENLRFHAEE EGSSKDADGN KVKADKDAVA 150
QFRKGLTALG DIYINDAFGT AHRAHSSMVG VDLPQKASGF LVKKELEYFA 200
KALEEPQRPF LAILGGSKVS DKIQLIDNLL PKVNSLIITG GMAFTFKKTL 250
ENVKIGSSLF DEAGSKIVGN IIEKAKKHNV KVVLPVDYVT ADKFAADAKT 300
GYATDEQGIP DGYMGLDVGE KSVESYKQTI AESKTILWNG PPGVFEMEPF 350
AKATKATLDA AVAAVQNGAT VIIGGGDTAT VAAKYGAEDK ISHVSTGGGA 400
SLELLEGKEL PGVAALSEKS K 421
Length:421
Mass (Da):44,909
Last modified:February 1, 1996 - v2
Checksum:iCBC948382ECE212D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M27549 Genomic DNA. Translation: AAA33318.1.
AACD01000017 Genomic DNA. Translation: EAA65839.1.
BN001308 Genomic DNA. Translation: CBF87861.1.
PIRiA24830.
RefSeqiXP_658850.1. XM_653758.1.

Genome annotation databases

EnsemblFungiiCADANIAT00001377; CADANIAP00001377; CADANIAG00001377.
GeneIDi2877015.
KEGGiani:AN1246.2.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M27549 Genomic DNA. Translation: AAA33318.1 .
AACD01000017 Genomic DNA. Translation: EAA65839.1 .
BN001308 Genomic DNA. Translation: CBF87861.1 .
PIRi A24830.
RefSeqi XP_658850.1. XM_653758.1.

3D structure databases

ProteinModelPortali P11977.
SMRi P11977. Positions 2-419.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 162425.CADANIAP00001377.

Proteomic databases

PRIDEi P11977.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii CADANIAT00001377 ; CADANIAP00001377 ; CADANIAG00001377 .
GeneIDi 2877015.
KEGGi ani:AN1246.2.

Phylogenomic databases

eggNOGi COG0126.
HOGENOMi HOG000227107.
KOi K00927.
OMAi FPVDYVT.
OrthoDBi EOG71K6D7.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Transcription and processing signals in the 3-phosphoglycerate kinase (PGK) gene from Aspergillus nidulans."
    Clements J.M., Roberts C.F.
    Gene 44:97-105(1986) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.
  3. "The 2008 update of the Aspergillus nidulans genome annotation: a community effort."
    Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J., Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M., Estrada C.G.
    , Geysens S., Goldman G., de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B., van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.
    Fungal Genet. Biol. 46:S2-13(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139.

Entry informationi

Entry nameiPGK_EMENI
AccessioniPrimary (citable) accession number: P11977
Secondary accession number(s): C8VSJ5, Q5BDY4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: February 1, 1996
Last modified: June 11, 2014
This is version 86 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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