Reviewed, UniProtKB/Swiss-Prot P11964 (SODCP_PEA)

Names and origin

Protein names

Recommended name:
    Superoxide dismutase [Cu-Zn], chloroplastic
    EC=1.15.1.1

Gene names

Name:	SODCP
Synonyms:	SOD2

Organism

Pisum sativum (Garden pea)

Taxonomic identifier

3888 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › eurosids I › Fabales › Fabaceae › Papilionoideae › Fabeae › Pisum

Protein attributes

Sequence length	202 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Catalytic activity	2 superoxide + 2 H+ = O2 + H2O2.
Cofactor	Binds 1 copper ion per subunit By similarity. Binds 1 zinc ion per subunit By similarity.
Subunit structure	Homotetramer.
Subcellular location	Plastid › chloroplast.
Sequence similarities	Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Ligand	Copper Metal-binding Zinc
Molecular function	Antioxidant Oxidoreductase
PTM	Disulfide bond
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW superoxide metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	antioxidant activity Inferred from electronic annotation. Source: UniProtKB-KW copper ion binding Inferred from electronic annotation. Source: UniProtKB-KW superoxide dismutase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 48	48	Chloroplast
	Chain	49 – 202	154	Superoxide dismutase [Cu-Zn], chloroplastic		PRO_0000032848
Sites
	Metal binding	94	1	Copper; catalytic By similarity
	Metal binding	96	1	Copper; catalytic By similarity
	Metal binding	111	1	Copper; catalytic By similarity
	Metal binding	111	1	Zinc; structural By similarity
	Metal binding	119	1	Zinc; structural By similarity
	Metal binding	128	1	Zinc; structural By similarity
	Metal binding	131	1	Zinc; structural By similarity
	Metal binding	168	1	Copper; catalytic By similarity
Amino acid modifications
	Disulfide bond	105 ↔ 194		By similarity
Natural variations
	Natural variant	55	1	S → A

Sequences

	Sequence		Length	Mass (Da)
	P11964-1 [UniParc]. Last modified October 1, 1989. Version 1. Checksum: 677BF4F185533A31	FASTA	202	20,626
	10 20 30 40 50 60 MASQTLVSPS PLSSHSLLRT SFSGVSVKLA PQFSTLATSN FKPLTVVAAA KKAVSVLKGT 70 80 90 100 110 120 SAVEGVVTLT QDDEGPTTVN VRITGLTPGL HGFHLHEYGD TTNGCISTGP HFNPNKLTHG 130 140 150 160 170 180 APEDEIRHAG DLGNIVANAE GVAEATIVDN QIPLTGPNSV VGRALVVHEL QDDLGKGGHE 190 200 LSLSTGNAGG RLACGVVGLT PV

References

[1]	"Cloning and characterization of a cDNA encoding the chloroplastic copper/zinc-superoxide dismutase from pea." Scioli J.R., Zilinskas B.A. Proc. Natl. Acad. Sci. U.S.A. 85:7661-7665(1988) [PubMed: 2845417] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"Sequence divergence of pea Cu/Zn superoxide dismutase II cDNAs." Isin S.H., Burke J.J., Allen R.D. Plant Mol. Biol. 15:789-791(1990) [PubMed: 2102887] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	J04087 mRNA. Translation: AAA33688.1. X56435 mRNA. Translation: CAA39819.1.
PIR	DSPMCZ. A30204.
3D structure databases
HSSP	HSSP built from PDB template 1SRD based on UniProtKB P07505.
SMR	P11964. Positions 49-202.
ModBase	Search...
Enzyme and pathway databases
BRENDA	1.15.1.1. 287.
Family and domain databases
InterPro	IPR018152. SOD_Cu/Zn_BS. IPR001424. SOD_Cu_Zn. [Graphical view]
Gene3D	G3DSA:2.60.40.200. SOD_Cu_Zn. 1 hit.
PANTHER	PTHR10003. SOD_Cu_Zn. 1 hit.
Pfam	PF00080. Sod_Cu. 1 hit. [Graphical view]
PRINTS	PR00068. CUZNDISMTASE.
ProDom	PD000469. SOD_CU_ZN. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS00087. SOD_CU_ZN_1. 1 hit. PS00332. SOD_CU_ZN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SODCP_PEA

Accession

Primary (citable) accession number: P11964

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
Last sequence update:	October 1, 1989
Last modified:	June 16, 2009
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)