P11901 (T421_ECOLX) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Transposase for insertion sequence element IS421
Organism	Escherichia coli
Taxonomic identifier	562 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	371 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the transposition of the insertion sequence IS421.
Sequence similarities	Belongs to the transposase 11 family.

Ontologies

Keywords
Biological process	DNA recombination Transposition
Ligand	DNA-binding
Technical term	Transposable element
Gene Ontology (GO)
Biological_process	transposition, DNA-mediated Inferred from electronic annotation. Source: InterPro
Molecular_function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW transposase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 371	371	Transposase for insertion sequence element IS421		PRO_0000173295

Sequences

	Sequence		Length	Mass (Da)
	P11901 [UniParc]. Last modified October 1, 1989. Version 1. Checksum: 2BD731641192DF38	FASTA	371	40,996
	10 20 30 40 50 60 MNYSHDNWSA ILAHIGKPEE LDTSARNAGA LTRRREIRDA ATLLRLGLAY GPGGMSSLRE 70 80 90 100 110 120 VTAWAQLHDV ATLSDVALLK RLRNAADWFG ILAAQTLAVR AAVTGCTSGK RLRLVDGTAI 130 140 150 160 170 180 SAPGGGSAEW RLHMGYDPHT CQFTDFELTD SRDAERLDRF AQTADEIRIA DRGFGSRPEC 190 200 210 220 230 240 IRSLAFGEAD YIVRVHWRGL RWLTAEGMRF DMMGFLRGLD CGKNGETTVM IGNSGNKKAG 250 260 270 280 290 300 APFPARLIAV SLPPEKALIS KTRLLSENRR KGRVVQAETL EAAGHVLLLT SLPEDEYSAE 310 320 330 340 350 360 QVADCYRLRW QIELAFKRLK SLLHLDALRA KEPELAKAWI FANLLAAFLI DDIIQPSLDF 370 PPRSAGSEKK N

References

[1]	"IS421, a new insertion sequence in Escherichia coli." Sato S., Nakada Y., Shiratsuchi A. FEBS Lett. 249:21-26(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: B and C.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Y07501 Genomic DNA. Translation: CAA68802.1.
PIR	S04880.
3D structure databases
ProteinModelPortal	P11901.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	COG3385.
Family and domain databases
Gene3D	3.90.350.10. 1 hit.
InterPro	IPR012337. RNaseH-like_dom. IPR002559. Transposase_11. IPR014736. Transposase_Tn5-like_core. [Graphical view]
Pfam	PF01609. DDE_Tnp_1. 1 hit. [Graphical view]
SUPFAM	SSF53098. RNaseH_fold. 1 hit.
ProtoNet	Search...

Entry information

Entry name

T421_ECOLX

Accession

Primary (citable) accession number: P11901

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
Last sequence update:	October 1, 1989
Last modified:	April 3, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program