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P11797

- CHIB_SERMA

UniProt

P11797 - CHIB_SERMA

Protein

Chitinase B

Gene

chiB

Organism
Serratia marcescens
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 1 (01 Oct 1989)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei144 – 1441Proton donorPROSITE-ProRule annotation

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro
    2. chitinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. chitin catabolic process Source: UniProtKB-KW
    2. polysaccharide catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Chitin degradation, Polysaccharide degradation

    Enzyme and pathway databases

    BioCyciMetaCyc:MONOMER-17689.
    BRENDAi3.2.1.14. 5690.
    SABIO-RKP11797.

    Protein family/group databases

    CAZyiCBM5. Carbohydrate-Binding Module Family 5.
    GH18. Glycoside Hydrolase Family 18.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chitinase B (EC:3.2.1.14)
    Gene namesi
    Name:chiB
    OrganismiSerratia marcescens
    Taxonomic identifieri615 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSerratia

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: InterPro

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 4141Add
    BLAST
    Chaini42 – 499458Chitinase BPRO_0000011909Add
    BLAST

    Interactioni

    Structurei

    Secondary structure

    1
    499
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi6 – 127
    Helixi15 – 195
    Turni26 – 283
    Helixi33 – 353
    Helixi38 – 436
    Beta strandi45 – 5410
    Beta strandi58 – 614
    Helixi68 – 8013
    Helixi81 – 844
    Beta strandi89 – 957
    Helixi97 – 1004
    Helixi107 – 1137
    Helixi117 – 13418
    Beta strandi137 – 1426
    Helixi148 – 17124
    Beta strandi180 – 1889
    Helixi189 – 1924
    Turni193 – 1953
    Helixi196 – 1983
    Helixi199 – 2035
    Beta strandi207 – 2126
    Beta strandi221 – 2233
    Beta strandi230 – 2323
    Helixi242 – 2454
    Helixi252 – 2587
    Beta strandi261 – 2633
    Helixi267 – 2759
    Helixi282 – 2843
    Beta strandi285 – 29814
    Beta strandi301 – 3033
    Turni304 – 3074
    Beta strandi315 – 3173
    Beta strandi319 – 3213
    Helixi329 – 3346
    Beta strandi339 – 3413
    Helixi342 – 3509
    Beta strandi353 – 3608
    Turni361 – 3644
    Beta strandi365 – 3706
    Turni371 – 3744
    Beta strandi375 – 3784
    Helixi382 – 39413
    Beta strandi399 – 4035
    Helixi405 – 4073
    Helixi413 – 42311
    Helixi445 – 4473
    Beta strandi467 – 4704
    Beta strandi473 – 4808
    Turni486 – 4883
    Beta strandi492 – 4976

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1E6NX-ray2.25A/B1-497[»]
    1GOIX-ray1.45A/B1-497[»]
    1H0GX-ray2.00A/B1-497[»]
    1H0IX-ray2.00A/B1-497[»]
    1O6IX-ray1.70A/B1-497[»]
    1OGBX-ray1.85A/B1-497[»]
    1OGGX-ray1.97A/B1-497[»]
    3WD0X-ray1.70A2-499[»]
    3WD1X-ray2.30A2-499[»]
    3WD2X-ray2.20A2-499[»]
    3WD3X-ray2.20A2-499[»]
    3WD4X-ray2.00A2-499[»]
    ProteinModelPortaliP11797.
    SMRiP11797. Positions 3-499.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP11797.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini438 – 49861Chitin-binding type-3Add
    BLAST

    Sequence similaritiesi

    Contains 1 chitin-binding type-3 domain.Curated

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di2.10.10.20. 1 hit.
    3.10.50.10. 1 hit.
    3.20.20.80. 2 hits.
    InterProiIPR003610. CBM_fam5/12.
    IPR011583. Chitinase_II.
    IPR029070. Chitinase_insertion.
    IPR001223. Glyco_hydro18cat.
    IPR001579. Glyco_hydro_18_chit_AS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF02839. CBM_5_12. 1 hit.
    PF00704. Glyco_hydro_18. 1 hit.
    [Graphical view]
    SMARTiSM00495. ChtBD3. 1 hit.
    SM00636. Glyco_18. 1 hit.
    [Graphical view]
    SUPFAMiSSF51055. SSF51055. 1 hit.
    SSF51445. SSF51445. 2 hits.
    SSF54556. SSF54556. 1 hit.
    PROSITEiPS01095. CHITINASE_18. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P11797-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTRKAVIGY YFIPTNQINN YTETDTSVVP FPVSNITPAK AKQLTHINFS    50
    FLDINSNLEC AWDPATNDAK ARDVVNRLTA LKAHNPSLRI MFSIGGWYYS 100
    NDLGVSHANY VNAVKTPAAR TKFAQSCVRI MKDYGFDGVD IDWEYPQAAE 150
    VDGFIAALQE IRTLLNQQTI ADGRQALPYQ LTIAGAGGAF FLSRYYSKLA 200
    QIVAPLDYIN LMTYDLAGPW EKITNHQAAL FGDAAGPTFY NALREANLGW 250
    SWEELTRAFP SPFSLTVDAA VQQHLMMEGV PSAKIVMGVP FYGRAFKGVS 300
    GGNGGQYSSH STPGEDPYPN ADYWLVGCDE CVRDKDPRIA SYRQLEQMLQ 350
    GNYGYQRLWN DKTKTPYLYH AQNGLFVTYD DAESFKYKAK YIKQQQLGGV 400
    MFWHLGQDNR NGDLLAALDR YFNAADYDDS QLDMGTGLRY TGVGPGNLPI 450
    MTAPAYVPGT TYAQGALVSY QGYVWQTKWG YITSAPGSDS AWLKVGRLA 499
    Length:499
    Mass (Da):55,464
    Last modified:October 1, 1989 - v1
    Checksum:iFFD674916109D1D8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X15208 Genomic DNA. Translation: CAA33278.1.
    AB015997 Genomic DNA. Translation: BAA31568.1.
    PIRiS04856.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X15208 Genomic DNA. Translation: CAA33278.1 .
    AB015997 Genomic DNA. Translation: BAA31568.1 .
    PIRi S04856.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1E6N X-ray 2.25 A/B 1-497 [» ]
    1GOI X-ray 1.45 A/B 1-497 [» ]
    1H0G X-ray 2.00 A/B 1-497 [» ]
    1H0I X-ray 2.00 A/B 1-497 [» ]
    1O6I X-ray 1.70 A/B 1-497 [» ]
    1OGB X-ray 1.85 A/B 1-497 [» ]
    1OGG X-ray 1.97 A/B 1-497 [» ]
    3WD0 X-ray 1.70 A 2-499 [» ]
    3WD1 X-ray 2.30 A 2-499 [» ]
    3WD2 X-ray 2.20 A 2-499 [» ]
    3WD3 X-ray 2.20 A 2-499 [» ]
    3WD4 X-ray 2.00 A 2-499 [» ]
    ProteinModelPortali P11797.
    SMRi P11797. Positions 3-499.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    BindingDBi P11797.
    ChEMBLi CHEMBL5348.

    Protein family/group databases

    CAZyi CBM5. Carbohydrate-Binding Module Family 5.
    GH18. Glycoside Hydrolase Family 18.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    BioCyci MetaCyc:MONOMER-17689.
    BRENDAi 3.2.1.14. 5690.
    SABIO-RK P11797.

    Miscellaneous databases

    EvolutionaryTracei P11797.

    Family and domain databases

    Gene3Di 2.10.10.20. 1 hit.
    3.10.50.10. 1 hit.
    3.20.20.80. 2 hits.
    InterProi IPR003610. CBM_fam5/12.
    IPR011583. Chitinase_II.
    IPR029070. Chitinase_insertion.
    IPR001223. Glyco_hydro18cat.
    IPR001579. Glyco_hydro_18_chit_AS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF02839. CBM_5_12. 1 hit.
    PF00704. Glyco_hydro_18. 1 hit.
    [Graphical view ]
    SMARTi SM00495. ChtBD3. 1 hit.
    SM00636. Glyco_18. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51055. SSF51055. 1 hit.
    SSF51445. SSF51445. 2 hits.
    SSF54556. SSF54556. 1 hit.
    PROSITEi PS01095. CHITINASE_18. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the chitinase B gene of Serratia marcescens QMB1466."
      Harpster M.H., Dunsmuir P.
      Nucleic Acids Res. 17:5395-5395(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 990 / QMB1466.
    2. "Genetic analysis of the chitinase system of Serratia marcescens 2170."
      Watanabe T., Kimura K., Sumiya T., Nikaidou N., Suzuki K., Suzuki M., Taiyoji M., Ferrer S., Regue M.
      J. Bacteriol. 179:7111-7117(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 2170.

    Entry informationi

    Entry nameiCHIB_SERMA
    AccessioniPrimary (citable) accession number: P11797
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1989
    Last sequence update: October 1, 1989
    Last modified: October 1, 2014
    This is version 98 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3