Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Capsid protein

Gene

ORF2

Organism
Tomato bushy stunt virus (strain BS-3) (TBSV)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid protein
Alternative name(s):
Coat protein
p41
Gene namesi
ORF Names:ORF2
OrganismiTomato bushy stunt virus (strain BS-3) (TBSV)
Taxonomic identifieri12146 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageTombusviridaeTombusvirus
Virus hostiCapsicum annuum (Bell pepper) [TaxID: 4072]
Malus [TaxID: 3749]
Pyrus (pears) [TaxID: 3766]
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081]
Solanum melongena (Eggplant) (Aubergine) [TaxID: 4111]
Tolmiea menziesii [TaxID: 29777]
Tulipa [TaxID: 13305]

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, T=3 icosahedral capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedSequence analysis
ChainiPRO_00002228662 – 388Capsid proteinAdd BLAST387

Post-translational modificationi

The N-terminus is blocked.Curated

Interactioni

Subunit structurei

Homomultimer.Curated

Structurei

Secondary structure

1388
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi95 – 97Combined sources3
Beta strandi109 – 116Combined sources8
Beta strandi119 – 123Combined sources5
Turni124 – 126Combined sources3
Beta strandi134 – 136Combined sources3
Helixi145 – 147Combined sources3
Turni148 – 150Combined sources3
Beta strandi151 – 168Combined sources18
Helixi192 – 195Combined sources4
Beta strandi206 – 208Combined sources3
Beta strandi210 – 213Combined sources4
Beta strandi224 – 226Combined sources3
Turni231 – 234Combined sources4
Beta strandi240 – 245Combined sources6
Beta strandi247 – 249Combined sources3
Beta strandi251 – 263Combined sources13
Beta strandi272 – 276Combined sources5
Beta strandi280 – 283Combined sources4
Beta strandi292 – 294Combined sources3
Beta strandi304 – 308Combined sources5
Beta strandi310 – 319Combined sources10
Beta strandi325 – 331Combined sources7
Beta strandi333 – 340Combined sources8
Beta strandi343 – 345Combined sources3
Beta strandi347 – 355Combined sources9
Beta strandi360 – 365Combined sources6
Beta strandi371 – 376Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2TBVX-ray2.90A/B/C2-388[»]
ProteinModelPortaliP11795.
SMRiP11795.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP11795.

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni2 – 102R domain, interaction with RNAAdd BLAST101
Regioni57 – 63Involved in encapsidationBy similarity7
Regioni103 – 264S domain, virion shellAdd BLAST162
Regioni265 – 388P domain, projectingAdd BLAST124

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi7 – 10Poly-Asn4

Sequence similaritiesi

Family and domain databases

Gene3Di2.60.120.20. 1 hit.
InterProiIPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view]
PfamiPF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSiPR00233. ICOSAHEDRAL.
PROSITEiPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P11795-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMTTRNNNN VLAISKKQLG VLAASAAVGA LRNHISESSP ALLQSAVGLG
60 70 80 90 100
KKALNKVRNR RKQGNQQIIT HVGGVGGSIM APVAVSRQLV GSKPKFTGRT
110 120 130 140 150
SGSVTVTHRE YLTQVNNSSG FVVNGGIVGN LLQLNPSNGT LFSWLPAIAS
160 170 180 190 200
NFDQYSFNSV VLHYVPLCGT TEVGRVALYF DKDSQDPEPA DRVELANFGV
210 220 230 240 250
LKETAPWAEA MLRIPTDKVK RYCNDSATVD QKLIDLGQLG IATYGGAGTN
260 270 280 290 300
AVGDVFISYS VTLYFPQPTN TLLSTRRLDL TGSLADATGP GYLVLTRTPT
310 320 330 340 350
VLTHTFRVTG TFNLSGGLRC LTSLTLGATG AVVINDILAI DNVGTASAYF
360 370 380
LNCTVSSLPA TVTFTTTGIS SATVNVVRGT RANVVNLL
Length:388
Mass (Da):40,911
Last modified:October 5, 2010 - v2
Checksum:i008DF490F253B79E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti14I → V AA sequence (PubMed:6481803).Curated1
Sequence conflicti34 – 36HIS → YIG AA sequence (PubMed:6481803).Curated3
Sequence conflicti107T → TG AA sequence (PubMed:6481803).Curated1
Sequence conflicti131L → S AA sequence (PubMed:6481803).Curated1
Sequence conflicti148I → L AA sequence (PubMed:6481803).Curated1
Sequence conflicti163H → D AA sequence (PubMed:6481803).Curated1
Sequence conflicti249 – 250TN → AD AA sequence (PubMed:6481803).Curated2
Sequence conflicti254 – 259DVFISY → ELFLAR AA sequence (PubMed:6481803).Curated6
Sequence conflicti275 – 276TR → SK AA sequence (PubMed:6481803).Curated2
Sequence conflicti308V → A AA sequence (PubMed:6481803).Curated1
Sequence conflicti348A → D AA sequence (PubMed:6481803).Curated1
Sequence conflicti366 – 380TTGIS…VVRGT → VSGVAAGILLVGRA AA sequence (PubMed:6481803).CuratedAdd BLAST15

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ271328 mRNA. Translation: CAB66390.1.
PIRiS07259.

Cross-referencesi

Web resourcesi

Virus Particle ExploreR db

Icosahedral capsid structure

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ271328 mRNA. Translation: CAB66390.1.
PIRiS07259.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2TBVX-ray2.90A/B/C2-388[»]
ProteinModelPortaliP11795.
SMRiP11795.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiP11795.

Family and domain databases

Gene3Di2.60.120.20. 1 hit.
InterProiIPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view]
PfamiPF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSiPR00233. ICOSAHEDRAL.
PROSITEiPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCAPSD_TBSVB
AccessioniPrimary (citable) accession number: P11795
Secondary accession number(s): Q9IW10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 5, 2010
Last modified: November 2, 2016
This is version 78 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.