Reviewed, UniProtKB/Swiss-Prot P11727 (OTCC_PSEPU)

Names and origin

Protein names

Recommended name:
    Ornithine carbamoyltransferase, catabolic
      Short name=OTCase
    EC=2.1.3.3

Gene names

Name:

arcB

Organism

Pseudomonas putida

Taxonomic identifier

303 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	34 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline. HAMAP MF_01109
Pathway	Amino-acid degradation; L-arginine degradation via ADI pathway; carbamoyl phosphate from L-arginine: step 2/2. HAMAP MF_01109
Subunit structure	Probably nonameric or dodecameric. HAMAP MF_01109
Subcellular location	Cytoplasm Probable.
Sequence similarities	Belongs to the ATCase/OTCase family.

Ontologies

Keywords
Biological process	Arginine metabolism
Cellular component	Cytoplasm
Molecular function	Transferase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	arginine metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ornithine carbamoyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.2
	Chain	2 – ›34	›33	Ornithine carbamoyltransferase, catabolic HAMAP MF_01109		PRO_0000112990
Sites
	Site	32	1	Important for structural integrity By similarity
Experimental info
	Non-terminal residue	34	1

Sequences

	Sequence		Length	Mass (Da)
	P11727-1 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: E4BB9FC2CD829DB7	FASTA	34	4,147
	10 20 30 MAFNIHNRNL LSLEHHTNRE LRYLLDLTRD LKAK

References

[1]	Wilson S.D., Wang M., Filpula D. Submitted (FEB-1994) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-13. Strain: ATCC 4359.
[2]	"Immunological and structural relatedness of catabolic ornithine carbamoyltransferases and the anabolic enzymes of enterobacteria." Falmagne P., Portetelle D., Stalon V. J. Bacteriol. 161:714-719(1985) [PubMed: 3968036] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-34.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U07185 Unassigned DNA. Translation: AAA16965.1.
PIR	D21897.
3D structure databases
HSSP	HSSP built from PDB template 1DXH based on UniProtKB P08308.
ModBase	Search...
Enzyme and pathway databases
BRENDA	2.1.3.3. 403.
Family and domain databases
HAMAP	MF_01109. [Tree]
InterPro	IPR006130. Asp/Orn_carbamoylTrfase. [Graphical view]
PROSITE	PS00097. CARBAMOYLTRANSFERASE. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

OTCC_PSEPU

Accession

Primary (citable) accession number: P11727

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
Last sequence update:	January 23, 2007
Last modified:	July 28, 2009
This is version 54 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)