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Reviewed, UniProtKB/Swiss-Prot P11701 (SACB_STRMU)

Last modified June 16, 2009. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Levansucrase
    EC=2.4.1.10
Alternative name(s):
    Beta-D-fructofuranosyl transferase
    Sucrose 6-fructosyl transferase
Gene names
Name: ftf
Synonyms: sacB
Ordered Locus Names: SMU_2028
OrganismStreptococcus mutans [Complete proteome] [HAMAP]
Taxonomic identifier1309 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

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Protein attributes

Sequence length795 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Sucrose + (6)-beta-D-fructofuranosyl-(2->)(n) alpha-D-glucopyranoside = glucose + (6)-beta-D-fructofuranosyl-(2->)(n+1) alpha-D-glucopyranoside.

Subcellular location

Secreted.

Sequence similarities

Belongs to the glycosyl hydrolase 68 family.

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Ontologies

Keywords
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processsugar utilization

Inferred from electronic annotation. Source: InterPro

   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionlevansucrase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3434
Chain35 – 795761Levansucrase
PRO_0000012250

Experimental info

Sequence conflict691D → A in AAA88584. Ref.1
Sequence conflict741K → Q in AAA88584. Ref.1
Sequence conflict1201S → A in AAA88584. Ref.1
Sequence conflict1311E → EKD in AAA88584. Ref.1
Sequence conflict375 – 3773GDG → VMA in AAA88584. Ref.1
Sequence conflict6411S → P in AAA88584. Ref.1
Sequence conflict7391Y → S in AAA88584. Ref.1

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Sequences

Sequence LengthMass (Da)Tools
P11701-1 [UniParc].

Last modified November 28, 2002. Version 2.
Checksum: 4012469148B34914

FASTA79587,385
        10         20         30         40         50         60 
METKVRKKMY KKGKFWVVAT ITTAMLTGIG LSSVQADEAN STQVSSELAE RSQVQENTTA 

        70         80         90        100        110        120 
SSSAAENQDK TEVKETPSTN PAAATVENTD QTTKVITDNA AVESKASKTK DQAATVTKTS 

       130        140        150        160        170        180 
ASTPEVGQTN EKAKATKEAD ITTPKNTIDE YGLTEQARKI ATEAGINLSS LTQKQVEALN 

       190        200        210        220        230        240 
KVKLTSDAQT GHQMTYQEFD KIAQTLIAQD ERYAIPYFNA KAIKNMKAAT TRDAQTGQIA 

       250        260        270        280        290        300 
DLDVWDSWPV QDAKTGEVIN WNGYQLVVAM MGIPNTNDNH IYLLYNKYGD NNFDHWKNAG 

       310        320        330        340        350        360 
SIFGYNETPL TQEWSGSATV NEDGSLQLFY TKVDTSDKNS NNQRLATATV NLGFDDQDVR 

       370        380        390        400        410        420 
ILSVENDKVL TPEGGDGYHY QSYQQWRSTF TGADNIAMRD PHVIEDENGD RYLVFEASTG 

       430        440        450        460        470        480 
TENYQGEDQI YNFTNYGGSS AYNVKSLFRF LDDQDMYNRA SWANAAIGIL KLKGDKKTPE 

       490        500        510        520        530        540 
VDQFYTPLLS STMVSDELER PNVVKLGDKY YLFTASRLNH GSNNDAWNKA NEVVGDNVVM 

       550        560        570        580        590        600 
LGYVSDQLTN GYKPLNNSGV VLTASVPADW RTATYSYYAV PVAGSSDTLL MTAYMTNRNE 

       610        620        630        640        650        660 
VAGKGKNSTW APSFLIQVLP DGTTKVLAEM TQQGDWIWDE SSRTTDTVGT LDTAYLPGEN 

       670        680        690        700        710        720 
DGYIDWNVIG GYGLKPHTPG QYQPTVPSTP IHTDDIISFE VSFDGHLVIK PVKVNNDSAG 

       730        740        750        760        770        780 
RIDQSRNSGG SLNVAFNVYA GGNISVKPSQ KSINNTKETK KAHHVSTEKK QKKGNSFFAA 

       790 
LLALFSAFCV SIGFK

« Hide

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References

« Hide 'large scale' references
[1]"Sequence analysis of the Streptococcus mutans fructosyltransferase gene and flanking regions."
Shiroza T., Kuramitsu H.K.
J. Bacteriol. 170:810-816(1988) [PubMed: 2828325] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: GS-5.
[2]"Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen."
Ajdic D.J., McShan W.M., McLaughlin R.E., Savic G., Chang J., Carson M.B., Primeaux C., Tian R., Kenton S., Jia H.G., Lin S.P., Qian Y., Li S., Zhu H., Najar F.Z., Lai H., White J., Roe B.A., Ferretti J.J.
Proc. Natl. Acad. Sci. U.S.A. 99:14434-14439(2002) [PubMed: 12397186] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 700610 / UA159 / Serotype c.

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Cross-references

Sequence databases

M18954 Genomic DNA. Translation: AAA88584.1.
AE014133 Genomic DNA. Translation: AAN59631.1.
PIRB28551.
RefSeqNP_722325.1.

3D structure databases

ModBaseSearch...

Protein family/group databases

CAZyGH68. Glycoside Hydrolase Family 68.

Genome annotation databases

GeneID1029219.
GenomeReviewsGene locus SMU_2028 in contig AE014133_GR.
KEGGsmu:SMU.2028.
NMPDRfig|210007.1.peg.1838.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMP11701.
OMAP11701. GADNIAM.

Enzyme and pathway databases

BioCycSMUT210007:SMU_2028-MON.
BRENDA2.4.1.10. 20716.

Family and domain databases

InterProIPR003469. Glyco_hydro_68.
[Graphical view]
PfamPF02435. Glyco_hydro_68. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameSACB_STRMU
AccessionPrimary (citable) accession number: P11701
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: November 28, 2002
Last modified: June 16, 2009
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents