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P11691 (MVP_TBSVC) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Protein attributes

Sequence length189 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Transports viral genome to neighboring plant cells directly through plasmosdesmata, without any budding. The movement protein allows efficient cell to cell propagation, by bypassing the host cell wall barrier. Displays RNA-binding activity. Ref.3

Subunit structure

Interacts with host protein HFI22. Ref.3

Subcellular location

Host membrane Ref.3.

Post-translational modification

Phosphorylated. Ref.3

Sequence similarities

Belongs to the tombusvirus/aureusvirus movement protein p22 family.

Ontologies

Keywords
   Biological processHost-virus interaction
Transport
   Cellular componentHost membrane
Membrane
   LigandRNA-binding
   Molecular functionViral movement protein
   PTMPhosphoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtransport of virus in host, cell to cell

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componenthost cell membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

membrane

Inferred from electronic annotation. Source: UniProtKB-KW

viral capsid

Inferred from electronic annotation. Source: InterPro

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 189189Movement protein
PRO_0000222891

Experimental info

Mutagenesis2 – 65DTEYE → ATAYA: Movement defective. No effect on interaction with host protein HFI22. No effect on association with host membrane. Ref.3
Mutagenesis32 – 354EDQE → AAQA: Movement defective. Loss of interaction with host protein HFI22. Ref.3
Mutagenesis1031E → A: Movement defective. Loss of interaction with host protein HFI22. No effect on association with host membrane. Ref.3

Sequences

Sequence LengthMass (Da)Tools
P11691 [UniParc].

Last modified October 1, 1989. Version 1.
Checksum: B9DE1C79465652F9

FASTA18921,608
        10         20         30         40         50         60 
MDTEYEQVNK PWNELYKETT LGNKLTVNVG MEDQEVPLLP SNFLTKVRVG LSGGYITMRR 

        70         80         90        100        110        120 
IRIKIIPLVS RKAGVSGKLY LRDISDTTGR KLHCTESLDL GREIRLTMQH LDFSVSTRSD 

       130        140        150        160        170        180 
VPIVFGFEEL VSPFLEGREL FSISVRWQFG LSKNCYSLPQ SKWKVMYQED ALKVLRPSKK 


KASKTDSSV 

« Hide

References

[1]"Organization of tomato bushy stunt virus genome: characterization of the coat protein gene and the 3' terminus."
Hillman B.I., Hearne P.Q., Rochon D., Morris T.J.
Virology 169:42-50(1989) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]"The complete genome structure and synthesis of infectious RNA from clones of tomato bushy stunt virus."
Hearne P.Q., Knorr D.A., Hillman B.I., Morris T.J.
Virology 177:141-151(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[3]"A novel plant homeodomain protein interacts in a functionally relevant manner with a virus movement protein."
Desvoyes B., Faure-Rabasse S., Chen M.H., Park J.W., Scholthof H.B.
Plant Physiol. 129:1521-1532(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION, SUBCELLULAR LOCATION, RNA-BINDING, PHOSPHORYLATION, MUTAGENESIS OF 2-ASP--GLU-6; 32-GLU--GLU-35 AND GLU-103, INTERACTION WITH NICOTIANA BENTHAMIANA PROTEIN HFI22.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M21958 Genomic RNA. Translation: AAB02537.1.
PIRNKVGTB. JA0115.
RefSeqNP_062900.1. NC_001554.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1493954.

Family and domain databases

InterProIPR005332. TBSV_p22.
[Graphical view]
PfamPF03558. TBSV_P22. 1 hit.
[Graphical view]
ProDomPD005327. TBSV_P22. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameMVP_TBSVC
AccessionPrimary (citable) accession number: P11691
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1989
Last modified: February 19, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families