P11689 (CAPSD_TBSVC) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Capsid protein

Alternative name(s):
Coat protein
p41

Gene names

ORF Names:

ORF2

Organism

Tomato bushy stunt virus (strain Cherry) (TBSV) [Reference proteome]

Taxonomic identifier

12147 [NCBI]

Taxonomic lineage

Viruses › ssRNA viruses › ssRNA positive-strand viruses, no DNA stage › Tombusviridae › Tombusvirus › Tomato bushy stunt virus

Virus host

Capsicum annuum (Bell pepper) [TaxID: 4072]
Malus [TaxID: 3749]
Pyrus (pears) [TaxID: 3766]
Solanum lycopersicum (Tomato) (Lycopersicon esculentum) [TaxID: 4081]
Solanum melongena (Eggplant) (Aubergine) [TaxID: 4111]
Tolmiea menziesii [TaxID: 29777]
Tulipa [TaxID: 13305]

Protein attributes

Sequence length	388 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins.
Subunit structure	Homomultimer Potential.
Subcellular location	Virion Potential.
Sequence similarities	Belongs to the icosahedral plant coat protein family.

Ontologies

Keywords
Cellular component	Virion
Ligand	RNA-binding
Molecular function	Capsid protein T=3 icosahedral capsid protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	T=3 icosahedral viral capsid Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	RNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural molecule activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 388	388	Capsid protein		PRO_0000222867
Regions
	Region	1 – 102	102	R domain, interaction with RNA
	Region	56 – 61	6	Involved in encapsidation By similarity
	Region	103 – 264	162	S domain, virion shell
	Region	265 – 388	124	P domain, projecting

Sequences

	Sequence		Length	Mass (Da)
	P11689 [UniParc]. Last modified October 1, 1989. Version 1. Checksum: 55C94E5C3C445A69	FASTA	388	41,151
	10 20 30 40 50 60 MAMVKRNNNT GMIPVSTKQL LALGAAAGAT ALQGFVKNNG MAIVEGAVDL TKRAYKAVRR 70 80 90 100 110 120 RGGKKQQMIN HVGGTGGAIM APVAVTRQLV GSKPKFTGRT SGSVTVTHRE YLSQVNNSTG 130 140 150 160 170 180 FQVNGGIVGN LLQLNPLNGT LFSWLPAIAS NFDQYTFNSV VLHYVPLCST TEVGRVAIYF 190 200 210 220 230 240 DKDSEDPEPA DRVELANYSV LKETAPWAEA MLRVPTDKIK RFCDDSSTSD HKLIDLGQLG 250 260 270 280 290 300 IATYGGAGTN AVGDIFISYS VTLYFPQPTN TLLSTRRLDL AGALVTASGP GYLLVSRTAT 310 320 330 340 350 360 VLTMTFRATG TFVISGTYRC LTATTLGLAG GVNVNSITVV DNIGTDSAFF INCTVSNLPS 370 380 VVTFTSTGIT SATVHCVRAT RQNDVSLI

References

[1]	"Organization of tomato bushy stunt virus genome: characterization of the coat protein gene and the 3' terminus." Hillman B.I., Hearne P.Q., Rochon D., Morris T.J. Virology 169:42-50(1989) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].
[2]	"The complete genome structure and synthesis of infectious RNA from clones of tomato bushy stunt virus." Hearne P.Q., Knorr D.A., Hillman B.I., Morris T.J. Virology 177:141-151(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M21958 Genomic RNA. Translation: AAB02536.1.
PIR	VCVGTB. JA0114.
RefSeq	NP_062899.1. NC_001554.1.
3D structure databases
ProteinModelPortal	P11689.
SMR	P11689. Positions 68-388.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1493953.
Family and domain databases
InterPro	IPR000937. Capsid_prot_S-dom_vir. [Graphical view]
Pfam	PF00729. Viral_coat. 1 hit. [Graphical view]
PRINTS	PR00233. ICOSAHEDRAL.
PROSITE	PS00555. ICOSAH_VIR_COAT_S. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPSD_TBSVC

Accession

Primary (citable) accession number: P11689

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
Last sequence update:	October 1, 1989
Last modified:	April 3, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program