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P11682 (APOB_CHICK) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Apolipoprotein B
Gene names
Name:APOB
OrganismGallus gallus (Chicken) [Reference proteome]
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length433 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Apolipoprotein B is a major protein constituent of chylomicrons, VLDL and LDL. It functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.

Subcellular location

Secreted.

Induction

Within 24 hours after estradiol administration, APOB mRNA is increased five- to seven-fold in liver but is unchanged in intestine and kidney.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 433›433Apolipoprotein B
PRO_0000064638

Amino acid modifications

Glycosylation1581N-linked (GlcNAc...) Potential

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
P11682 [UniParc].

Last modified October 1, 1989. Version 1.
Checksum: FD8808C9CFF48925

FASTA43350,848
        10         20         30         40         50         60 
IPGLSEKYTG EELYLMTTEK AAKTADICLS KLQEYFDALI AAISELEVRV PASETILRGR 

        70         80         90        100        110        120 
NVLDQIKEML KHLQEKIRQT FVTLQEADFA GKLNRLKQVV QKTFQKAGNM VRSLQSKNFE 

       130        140        150        160        170        180 
DIKVQMQQLY KDAMASDYAH KLRSLAENVK KYISQIKNFS QKTLQKLSEN LQQLVLYIKA 

       190        200        210        220        230        240 
LREEYFDPTT LGWSVKYYEV EDKVLGLLKN LMDTLVIWYN EYAKDLSDLV TRLTDQVREL 

       250        260        270        280        290        300 
VENYRQEYYD LITDVEGKGR QKVMELSSAA QEKIRYWSAV AKRKINEHNR QVKAKLQEIY 

       310        320        330        340        350        360 
GQLSDSQEKL INVAKMLIDL TVEKYSTFMK YIFELLRWFE QATADSIKPY IAVREGELRI 

       370        380        390        400        410        420 
DVPFDWEYIN QMPQKSREAL RNKVELTRAL IQQGVEQGTR KWEEMQAFID EQLATEQLSF 

       430 
QQIVENIQKR MKT 

« Hide

References

[1]"Regulation of chicken apolipoprotein B: cloning, tissue distribution, and estrogen induction of mRNA."
Kirchgessner T.G., Heinzmann C., Svenson K.L., Gordon D.A., Nicosia M., Lebherz H.G., Lusis A.J., Williams D.L.
Gene 59:241-251(1987) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M18421 mRNA. Translation: AAA48595.1.
PIRA29626.
UniGeneGga.4112.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9031.ENSGALP00000026550.

Proteomic databases

PaxDbP11682.
PRIDEP11682.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGNOG290405.

Family and domain databases

InterProIPR022176. ApoB100_C.
[Graphical view]
PfamPF12491. ApoB100_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROP11682.

Entry information

Entry nameAPOB_CHICK
AccessionPrimary (citable) accession number: P11682
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1989
Last modified: January 22, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program