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Reviewed, UniProtKB/Swiss-Prot P11681 (ABL_CALVI)

Last modified February 9, 2010. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Tyrosine-protein kinase ABL
    EC=2.7.10.2
Gene names
Name: ABL
OrganismCalliphora vicina (Blue blowfly) (Calliphora erythrocephala)
Taxonomic identifier7373 [NCBI]
Taxonomic lineageEukaryotaMetazoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaOestroideaCalliphoridaeCalliphorinaeCalliphora

Protein attributes

Sequence length74 AA.
Sequence statusFragment.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.

Subcellular location

Cytoplasm.

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family. ABL subfamily.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – ›74›74Tyrosine-protein kinase ABL
PRO_0000088053

Regions

Domain‹1 – ›74›74Protein kinase
Motif50 – 7425Kinase activation loop By similarity

Sites

Active site321Proton acceptor By similarity

Experimental info

Non-terminal residue11
Non-terminal residue741

Sequences

Sequence LengthMass (Da)Tools
P11681-1 [UniParc].

Last modified October 1, 1989. Version 1.
Checksum: DBF86E8D35001CCA

FASTA748,303
        10         20         30         40         50         60 
RETLDAVALL YMATQIASGM SYLEARNYIH RDLAARNCLV GDNKLVKVAD FGLARLMRDD 

        70 
TYTAHAGAKF PIKW 

« Hide

References

[1]"Isolation and characterization of abl gene sequences in Calliphora erythrocephala."
Durica D.S., Restrepo M.A., Thomas T.L., Beckingham K.
Gene 59:63-76(1987) [PubMed: 3125084] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M18427 Genomic DNA. Translation: AAA28232.1.
PIRA29597.

3D structure databases

SMRP11681. Positions 1-74.
ModBaseSearch...

Proteomic databases

PRIDEP11681.

Enzyme and pathway databases

BRENDA2.7.10.2. 2654.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_cat_dom.
IPR020700. Tyr_kinase_non-rcpt_Abl.
IPR020685. Tyr_prot_kinase.
IPR008266. Tyr_prot_kinase_AS.
[Graphical view]
PANTHERPTHR23256:SF144. Tyr_kinase_non-rcpt_Abl. 1 hit.
PTHR23256. Tyr_prot_kinase. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. Partial match.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameABL_CALVI
AccessionPrimary (citable) accession number: P11681
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: October 1, 1989
Last modified: February 9, 2010
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents