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P11636 (QAY_NEUCR) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Quinate permease
Alternative name(s):
Quinate transporter
Gene names
Name:qa-y
ORF Names:NCU06026
OrganismNeurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Taxonomic identifier367110 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Sordariomycetes › Sordariomycetidae › Sordariales › Sordariaceae › Neurospora

Protein attributes

Sequence length537 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]

Ontologies

Keywords
   Biological processQuinate metabolism
Transport
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   PTMGlycoprotein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processquinate metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionsubstrate-specific transmembrane transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 537537Quinate permease
PRO_0000050449

Regions

Topological domain1 – 2626Cytoplasmic Potential
Transmembrane27 – 4721Helical; Name=1; Potential
Topological domain48 – 7427Extracellular Potential
Transmembrane75 – 9521Helical; Name=2; Potential
Topological domain96 – 983Cytoplasmic Potential
Transmembrane99 – 11921Helical; Name=3; Potential
Topological domain120 – 13112Extracellular Potential
Transmembrane132 – 15221Helical; Name=4; Potential
Topological domain153 – 1608Cytoplasmic Potential
Transmembrane161 – 18121Helical; Name=5; Potential
Topological domain182 – 19514Extracellular Potential
Transmembrane196 – 21621Helical; Name=6; Potential
Topological domain217 – 28569Cytoplasmic Potential
Transmembrane286 – 30621Helical; Name=7; Potential
Topological domain307 – 32721Extracellular Potential
Transmembrane328 – 34922Helical; Name=8; Potential
Topological domain350 – 3523Cytoplasmic Potential
Transmembrane353 – 37321Helical; Name=9; Potential
Topological domain374 – 38916Extracellular Potential
Transmembrane390 – 41021Helical; Name=10; Potential
Topological domain411 – 43525Cytoplasmic Potential
Transmembrane436 – 45621Helical; Name=11; Potential
Topological domain457 – 4582Extracellular Potential
Transmembrane459 – 47921Helical; Name=12; Potential
Topological domain480 – 53758Cytoplasmic Potential

Amino acid modifications

Glycosylation1841N-linked (GlcNAc...) Potential

Experimental info

Sequence conflict4811E → V in CAA32752. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P11636 [UniParc].

Last modified April 13, 2004. Version 2.
Checksum: 89D53413EFC164F3

FASTA53760,134
        10         20         30         40         50         60 
MTLLALKEDR PTPKAVYNWR VYTCAAIASF ASCMIGYDSA FIGTTLALPS FTKEFDFASY 

        70         80         90        100        110        120 
TPGALALLQS NIVSVYQAGA FFGCLFAYAT SYFLGRRKSL IAFSVVFIIG AAIMLAADGQ 

       130        140        150        160        170        180 
GRGIDPIIAG RVLAGIGVGG ASNMVPIYIS ELAPPAVRGR LVGIYELGWQ IGGLVGFWIN 

       190        200        210        220        230        240 
YGVNTTMAPT RSQWLIPFAV QLIPAGLLFL GSFWIPESPR WLYANGKREE AMKVLCWIRN 

       250        260        270        280        290        300 
LEPTDRYIVQ EVSFIDADLE RYTRQVGNGF WKPFLSLKQR KVQWRFFLGG MLFFWQNGSG 

       310        320        330        340        350        360 
INAINYYSPT VFRSIGITGT DTGFLTTGIF GVVKMVLTII WLLWLVDLVG RRRILFIGAA 

       370        380        390        400        410        420 
GGSLCMWFIG AYIKIADPGS NKAEDAKLTS GGIAAIFFFY LWTAFYTPSW NGTPWVINSE 

       430        440        450        460        470        480 
MFDQNTRSLG QASAAANNWF WNFIISRFTP QMFIKMEYGV YFFFASLMLL SIVFIYFFLP 

       490        500        510        520        530 
ETKSIPLEAM DRLFEIKPVQ NANKNLMAEL NFDRNPEREE SSSLDDKDRV TQTENAV

« Hide

References

« Hide 'large scale' references
[1]"DNA sequence, organization and regulation of the qa gene cluster of Neurospora crassa."
Geever R.F., Huiet L., Baum J.A., Tyler B.M., Patel V.B., Rutledge B.J., Case M.E., Giles N.H.
J. Mol. Biol. 207:15-34(1989) [PubMed: 2525625] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987.
[2]"The genome sequence of the filamentous fungus Neurospora crassa."
Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., Qui D. expand/collapse author list , Ianakiev P., Bell-Pedersen D., Nelson M.A., Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.
Nature 422:859-868(2003) [PubMed: 12712197] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		X14603 Genomic DNA. Translation: CAA32752.1.
AABX02000021 Genomic DNA. Translation: EAA30380.1.
PIRG31277. S04254.
RefSeqXP_959616.1. XM_954523.1.

3D structure databases

ProteinModelPortalP11636.
ModBaseSearch...

Protein-protein interaction databases

STRINGP11636.

Protein family/group databases

TCDB2.A.1.1.7. major facilitator superfamily (MFS).

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiEFNCRT00000005341; EFNCRP00000005335; EFNCRG00000005334.
GeneID3875775.
KEGGncr:NCU06026.
NMPDRfig|5141.1.peg.3814.

Phylogenomic databases

eggNOGfuNOG05822.
GeneTreeEFGT00070000008710.
OMAGIYELGW.
OrthoDBEOG41ZJK8.

Enzyme and pathway databases

BioCycNCRA-XX3-01:NCRA-XX3-01-009774-MONOMER.

Family and domain databases

InterProIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSPR00171. SUGRTRNSPORT.
SUPFAMSSF103473. MFS_gen_substrate_transporter. 1 hit.
TIGRFAMsTIGR00879. SP. 1 hit.
PROSITEPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQAY_NEUCR
AccessionPrimary (citable) accession number: P11636
Secondary accession number(s): Q7RVA0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1989
Last sequence update: April 13, 2004
Last modified: December 14, 2011
This is version 97 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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