P11582 (GLBE_CHITH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Globin CTT-E/E'

Gene names

Name:	CTT-E
AND
Name:	CTT-E'

Organism

Chironomus thummi thummi (Midge)

Taxonomic identifier

7155 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Protostomia › Ecdysozoa › Panarthropoda › Arthropoda › Mandibulata › Pancrustacea › Hexapoda › Insecta › Dicondylia › Pterygota › Neoptera › Endopterygota › Diptera › Nematocera › Culicimorpha › Chironomoidea › Chironomidae › Chironominae › Chironomini › Chironomus › Chironomus › Chironomus thummi

Protein attributes

Sequence length	152 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the globin family.

Ontologies

Keywords
Biological process	Oxygen transport Transport
Domain	Signal
Ligand	Heme Iron Metal-binding
Gene Ontology (GO)
Cellular_component	extracellular region Inferred from electronic annotation. Source: InterPro hemoglobin complex Inferred from electronic annotation. Source: InterPro
Molecular_function	heme binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro oxygen binding Inferred from electronic annotation. Source: InterPro oxygen transporter activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 15	15
	Chain	16 – 152	137	Globin CTT-E/E'		PRO_0000011212
Sites
	Metal binding	73	1	Iron (heme distal ligand) By similarity
	Metal binding	102	1	Iron (heme proximal ligand) By similarity

Sequences

	Sequence		Length	Mass (Da)
	P11582 [UniParc]. Last modified October 1, 1989. Version 1. Checksum: 52D70B8CF57CFA9E	FASTA	152	15,964
	10 20 30 40 50 60 MKFIILALCV AAASALSGDQ IGLVQSTYGK VKGDSVGILY AVFKADPTIQ AAFPQFVGKD 70 80 90 100 110 120 LDAIKGGAEF STHAGRIVGF LGGVIDDLPN IGKHVDALVA THKPRGVTHA QFNNFRAAFI 130 140 150 AYLKGHVDYT AAVEAAWGAT FDAFFGAVFA KM

References

[1]	"Genomic organization and primary structure of five homologous pairs of intron-less genes encoding secretory globins from the insect Chironomus thummi thummi." Antoine M., Erbil C., Muench E., Schnell S., Niessing J. Gene 56:41-51(1987) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	Hankeln T., Amid C., Weich B., Schmidt E.R. Submitted (JAN-1997) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	M17604 Genomic DNA. Translation: AAA28253.1. M17695 Genomic DNA. Translation: AAA28258.1. Y10622 Genomic DNA. Translation: CAA71643.1.
3D structure databases
ProteinModelPortal	P11582.
SMR	P11582. Positions 16-152.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.490.10. 1 hit.
InterPro	IPR002336. Erythrocruorin. IPR000971. Globin. IPR009050. Globin-like. IPR012292. Globin_dom. [Graphical view]
Pfam	PF00042. Globin. 1 hit. [Graphical view]
PRINTS	PR00611. ERYTHCRUORIN.
SUPFAM	SSF46458. Globin_like. 1 hit.
PROSITE	PS01033. GLOBIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLBE_CHITH

Accession

Primary (citable) accession number: P11582

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 1, 1989
Last sequence update:	October 1, 1989
Last modified:	April 3, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)