P11557 (DAMX_ECOLI) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 101.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Protein DamX | ||||||
| Gene names |
| ||||||
| Organism | Escherichia coli (strain K12) [Reference proteome] [HAMAP] | ||||||
| Taxonomic identifier | 83333 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia › ![]() |
Protein attributes
| Sequence length | 428 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Directly or indirectly interferes with cell division. |
| Subcellular location | Cell membrane; Single-pass membrane protein Potential. |
| Sequence similarities | Contains 1 SPOR domain. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Cell cycle Cell division |
| Cellular component | Cell membrane Membrane |
| Domain | Transmembrane Transmembrane helix |
| Technical term | 3D-structure Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | cell cycle Inferred from electronic annotation. Source: UniProtKB-KW cytokinesisInferred from mutant phenotype Ref.2. Source: EcoCyc |
| Cellular_component | cell division site part Inferred from direct assay PubMed 19684127. Source: EcoCyc integral to membraneInferred from electronic annotation. Source: UniProtKB-KW plasma membraneInferred from electronic annotation. Source: UniProtKB-SubCell |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||||||||||||
Molecule processing | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 428 | 428 | Protein DamX | PRO_0000079779 | |||||||||||||||||
Regions | |||||||||||||||||||||
| Transmembrane | 104 – 124 | 21 | Helical; Potential | ||||||||||||||||||
| Domain | 345 – 417 | 73 | SPOR | ||||||||||||||||||
Experimental info | |||||||||||||||||||||
| Sequence conflict | 6 | 1 | P → T Ref.1 | ||||||||||||||||||
| Sequence conflict | 6 | 1 | P → T Ref.2 | ||||||||||||||||||
| Sequence conflict | 31 | 1 | R → P Ref.1 | ||||||||||||||||||
| Sequence conflict | 31 | 1 | R → P Ref.2 | ||||||||||||||||||
| Sequence conflict | 86 – 91 | 6 | RRPRKR → LVRVS Ref.1 | ||||||||||||||||||
| Sequence conflict | 86 – 91 | 6 | RRPRKR → LVRVS Ref.2 | ||||||||||||||||||
| Sequence conflict | 233 | 1 | V → L in CAA79667. Ref.2 | ||||||||||||||||||
| Sequence conflict | 310 | 1 | A → V Ref.1 | ||||||||||||||||||
| Sequence conflict | 310 | 1 | A → V Ref.2 | ||||||||||||||||||
| Sequence conflict | 366 | 1 | K → N in CAA79667. Ref.2 | ||||||||||||||||||
| Sequence conflict | 382 | 1 | G → V Ref.1 | ||||||||||||||||||
| Sequence conflict | 382 | 1 | G → V Ref.2 | ||||||||||||||||||
Secondary structure | |||||||||||||||||||||
Helix Strand Turn | |||||||||||||||||||||
| Helix | 358 – 367 | 10 | |||||||||||||||||||
| Beta strand | 380 – 383 | 4 | |||||||||||||||||||
| Beta strand | 393 – 395 | 3 | |||||||||||||||||||
| Helix | 396 – 405 | 10 | |||||||||||||||||||
| Helix | 408 – 411 | 4 | |||||||||||||||||||
| Turn | 420 – 422 | 3 | |||||||||||||||||||
| Helix | 423 – 425 | 3 | |||||||||||||||||||
Sequences
| ||||||||||||||||||
References
Cross-references
Sequence databases | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EMBL GenBank DDBJ | X15162 Genomic DNA. Translation: CAA33253.1. Z19601 Genomic DNA. Translation: CAA79667.1. U18997 Genomic DNA. Translation: AAA58185.1. U00096 Genomic DNA. Translation: AAC76413.1. AP009048 Genomic DNA. Translation: BAE77903.1. | ||||||||||||
| PIR | Q4ECAD. G65133. | ||||||||||||
| RefSeq | NP_417847.1. NC_000913.2. YP_492044.1. NC_007779.1. | ||||||||||||
3D structure databases | |||||||||||||
| PDBe RCSB PDB PDBj |
| ||||||||||||
| ProteinModelPortal | P11557. | ||||||||||||
| SMR | P11557. Positions 340-427. | ||||||||||||
| ModBase | Search... | ||||||||||||
Protein-protein interaction databases | |||||||||||||
| DIP | DIP-9397N. | ||||||||||||
| IntAct | P11557. 22 interactions. | ||||||||||||
| STRING | 511145.b3388. | ||||||||||||
Proteomic databases | |||||||||||||
| PaxDb | P11557. | ||||||||||||
| PRIDE | P11557. | ||||||||||||
Protocols and materials databases | |||||||||||||
| StructuralBiologyKnowledgebase | Search... | ||||||||||||
Genome annotation databases | |||||||||||||
| EnsemblBacteria | AAC76413; AAC76413; b3388. BAE77903; BAE77903; BAE77903. | ||||||||||||
| GeneID | 12933967. 947930. | ||||||||||||
| KEGG | ecj:Y75_p3788. eco:b3388. | ||||||||||||
| PATRIC | 32122208. VBIEscCol129921_3481. | ||||||||||||
Organism-specific databases | |||||||||||||
| EchoBASE | EB1170. | ||||||||||||
| EcoGene | EG11183. damX. | ||||||||||||
Phylogenomic databases | |||||||||||||
| eggNOG | COG3266. | ||||||||||||
| HOGENOM | HOG000125518. | ||||||||||||
| KO | K03112. | ||||||||||||
| OMA | KPDTSDR. | ||||||||||||
| ProtClustDB | PRK10905. | ||||||||||||
Enzyme and pathway databases | |||||||||||||
| BioCyc | EcoCyc:EG11183-MONOMER. ECOL316407:JW3351-MONOMER. | ||||||||||||
Gene expression databases | |||||||||||||
| Genevestigator | P11557. | ||||||||||||
Family and domain databases | |||||||||||||
| Gene3D | 3.30.70.1070. 1 hit. | ||||||||||||
| InterPro | IPR007730. Sporulation-related_dom. [Graphical view] | ||||||||||||
| Pfam | PF05036. SPOR. 1 hit. [Graphical view] | ||||||||||||
| SUPFAM | SSF110997. Spore_cell-division_bac. 1 hit. | ||||||||||||
| ProtoNet | Search... | ||||||||||||
Entry information
| Entry name | DAMX_ECOLI | ||||||||
| Accession | Primary (citable) accession number: P11557 Secondary accession number(s): P76687, Q2M753 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| Escherichia coli Escherichia coli (strain K12): entries and cross-references to EcoGene |
| PDB cross-references Index of Protein Data Bank (PDB) cross-references |
| SIMILARITY comments Index of protein domains and families |

Clusters with
