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Protein

PBAN-type neuropeptides

Gene
N/A
Organism
Helicoverpa zea (Corn earworm moth) (Heliothis zea)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

A hormone that controls sex pheromone production in females and pheromone responsiveness in male. Also mediates visceral muscle contractile activity (myotropic activity).2 Publications

Miscellaneous

Juvenile hormone seems to allow PBAN release, which then induces pheromone biosynthesis.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHormone, Neuropeptide
Biological processPheromone response

Names & Taxonomyi

Protein namesi
Recommended name:
PBAN-type neuropeptides
Alternative name(s):
Pheromone/pyrokinin biosynthesis-activating neuropeptide
Cleaved into the following 5 chains:
Alternative name(s):
Pyrokinin-1
Alternative name(s):
Pyrokinin-2
Alternative name(s):
Pyrokinin-3
Alternative name(s):
Pyrokinin-4
OrganismiHelicoverpa zea (Corn earworm moth) (Heliothis zea)
Taxonomic identifieri7113 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaLepidopteraGlossataDitrysiaNoctuoideaNoctuidaeHeliothinaeHelicoverpa

Subcellular locationi

  • Secreted 1 Publication

GO - Cellular componenti

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
PeptideiPRO_000002993624 – 47Diapause hormone homologSequence analysisAdd BLAST24
PropeptideiPRO_000002993751 – 94Add BLAST44
PeptideiPRO_000002993897 – 103Alpha-SG neuropeptideSequence analysis7
PeptideiPRO_0000029939106 – 123Beta-SG neuropeptideSequence analysisAdd BLAST18
PeptideiPRO_0000029940127 – 159Pheromone biosynthesis-activating neuropeptideAdd BLAST33
PeptideiPRO_0000029941162 – 169Gamma-SG neuropeptideSequence analysis8
PropeptideiPRO_0000029942172 – 194Add BLAST23

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei47Leucine amide1 Publication1
Modified residuei103Leucine amide1 Publication1
Modified residuei123Leucine amide1 Publication1
Modified residuei159Leucine amide1 Publication1 Publication1
Modified residuei169Leucine amide1 Publication1

Keywords - PTMi

Amidation, Cleavage on pair of basic residues

Expressioni

Tissue specificityi

Expressed in the subesophageal ganglions. Not found in corpora cardiaca, corpora allata and thoracic ganglia.1 Publication

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliP11159.
SMRiP11159.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pyrokinin family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiView protein in InterPro
IPR008730. PBAN.
IPR001484. Pyrokinin_CS.
PfamiView protein in Pfam
PF05874. PBAN. 1 hit.
PROSITEiView protein in PROSITE
PS00539. PYROKININ. 4 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P11159-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFNQTQLFVF LAVFTTSSVL GNNNDVKDGA ASGAHSDRLG LWFGPRLGKR
60 70 80 90 100
SLRISTEDNR QAFFKLLEAA DALKYYYDQL PYEMQADEPE TRVTKKVIFT
110 120 130 140 150
PKLGRSLAYD DKSFENVEFT PRLGRRLSDD MPATPADQEM YRQDPEQIDS
160 170 180 190
RTKYFSPRLG RTMNFSPRLG RELSYDMMPN KIRVVRSTNK TRST
Length:194
Mass (Da):22,373
Last modified:May 30, 2000 - v2
Checksum:iB120B81B39B4B5D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U08109 mRNA. Translation: AAA20661.1.
PIRiA55756.

Similar proteinsi

Entry informationi

Entry nameiPBAN_HELZE
AccessioniPrimary (citable) accession number: P11159
Secondary accession number(s): Q25200
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: May 30, 2000
Last modified: August 30, 2017
This is version 73 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families