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Reviewed, UniProtKB/Swiss-Prot P11148 (COL_CHICK)

Last modified July 22, 2008. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Colipase
Gene names
Name: CLPS
OrganismGallus gallus (Chicken)
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus

Protein attributes

Sequence length34 AA.
Sequence statusFragment.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.

Subunit structure

Forms a 1:1 stoichiometric complex with pancreatic lipase.

Subcellular location

Secreted.

Tissue specificity

Expressed by the pancreas.

Sequence similarities

Belongs to the colipase family.

Ontologies

Keywords

   Biological processDigestion
Lipid degradation
   Cellular componentSecreted
   Technical termDirect protein sequencing

Gene Ontology (GO)

None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical view

Molecule processing

Chain1 – ›34›34Colipase

Amino acid modifications

Disulfide bond12 ↔ 23 By similarity
Disulfide bond18 ↔ 34 By similarity

Experimental info

Sequence uncertainty121
Non-terminal residue341

Sequences

Sequence LengthMass (Da)Tools
P11148-1 [UniParc].

Last modified December 1, 1992. Version 2.
Checksum: 4A646B55FCB83BEB

FASTA343,591
        10         20         30 
GLIFNLDTGE LCLQSAQCKS ECCQEDSGLS LAXC 

« Hide

References

[1]"Evidence for the existence of procolipase in chicken pancreas and pancreatic juice."
Bosc-Bierne I., Rathelot J., Bechis G., Delori P., Sarda L.
Biochimie 66:413-416(1984) [PubMed: 6547861] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Pancreas.
[2]"Isolation and partial structural characterization of chicken pancreatic colipase."
Bosc-Bierne I., Rathelot J., Canioni P., Julien R., Bechis G., Gregorie J., Rochat H., Sarda L.
Biochim. Biophys. Acta 667:225-232(1981) [PubMed: 7213802] [Abstract]
Cited for: PROTEIN SEQUENCE.
Tissue: Pancreas.

Cross-references

Sequence databases

PIRA05330.
UniGeneGga.6607

3D structure databases

HSSPHSSP built from PDB template 1LPB based on UniProtKB P02703.
ModBaseSearch...

Genome annotation databases

EnsemblENSGALG00000000900. Gallus gallus. [Contig view]

Phylogenomic databases

HOGENOMP11148.
HOVERGENP11148.

Family and domain databases

InterProIPR001981. Colipase.
[Graphical view]
PfamPF01114. Colipase. 1 hit.
[Graphical view]
PROSITEPS00121. COLIPASE_1. Partial match.
PS51342. COLIPASE_2. 1 hit.
[Graphical view]
BLOCKSSearch...

Other Resources

ProtoNetSearch...

Entry information

Entry nameCOL_CHICK
AccessionPrimary (citable) accession number: P11148
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: December 1, 1992
Last modified: July 22, 2008
This is version 45 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents