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Protein

Flagellar filament 41 kDa core protein

Gene

fla

Organism
Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of the core of the flagella.

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar filament 41 kDa core protein
Short name:
Flagellin
Alternative name(s):
41 kDa antigen
P41
Gene namesi
Name:fla
Ordered Locus Names:BB_0147
OrganismiBorrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
Taxonomic identifieri224326 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesBorreliaceaeBorreliella
Proteomesi
  • UP000001807 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • bacterial-type flagellum filament Source: InterPro
  • membrane Source: CAFA
  • periplasmic flagellum Source: UniProtKB-SubCell

Keywords - Cellular componenti

Bacterial flagellum, Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001825901 – 336Flagellar filament 41 kDa core proteinAdd BLAST336

Proteomic databases

PRIDEiP11089.

Interactioni

Subunit structurei

The flagellum consists of an outer layer composed of repeating units of FlaA around a core that contains several antigenically related polypeptides.

Protein-protein interaction databases

STRINGi224326.BB_0147.

Structurei

3D structure databases

ProteinModelPortaliP11089.
SMRiP11089.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial flagellin family.Curated

Phylogenomic databases

eggNOGiENOG4105I03. Bacteria.
COG1344. LUCA.
KOiK02406.
OMAiFEHTINN.

Family and domain databases

InterProiView protein in InterPro
IPR001444. Flag_bb_rod_N.
IPR019776. Flagellar_basal_body_rod_CS.
IPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
PfamiView protein in Pfam
PF00700. Flagellin_C. 1 hit.
PF00669. Flagellin_N. 1 hit.
PF00460. Flg_bb_rod. 1 hit.
PRINTSiPR00207. FLAGELLIN.
PROSITEiView protein in PROSITE
PS00588. FLAGELLA_BB_ROD. 1 hit.

Sequencei

Sequence statusi: Complete.

P11089-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIINHNTSAI NASRNNGINA ANLSKTQEKL SSGYRINRAS DDAAGMGVSG
60 70 80 90 100
KINAQIRGLS QASRNTSKAI NFIQTTEGNL NEVEKVLVRM KELAVQSGNG
110 120 130 140 150
TYSDADRGSI QIEIEQLTDE INRIADQAQY NQMHMLSNKS ASQNVRTAEE
160 170 180 190 200
LGMQPAKINT PASLSGSQAS WTLRVHVGAN QDEAIAVNIY AANVANLFSG
210 220 230 240 250
EGAQTAQAAP VQEGVQQEGA QQPAPATAPS QGGVNSPVNV TTTVDANTSL
260 270 280 290 300
AKIENAIRMI SDQRANLGAF QNRLESIKDS TEYAIENLKA SYAQIKDATM
310 320 330
TDEVVAATTN SILTQSAMAM IAQANQVPQY VLSLLR
Length:336
Mass (Da):35,766
Last modified:July 1, 1989 - v1
Checksum:i3EE4A15CC1D361E9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti180N → T in CAA33696 (PubMed:2341173).Curated1
Sequence conflicti180N → T in CAA34735 (PubMed:2341173).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti156A → S in strain: 212. 1
Natural varianti279D → N in strain: B31 and KA. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X15660 Genomic DNA. Translation: CAA33695.1.
X15661 Genomic DNA. Translation: CAA33696.1.
X16833 Genomic DNA. Translation: CAA34735.1.
X56334 Genomic DNA. Translation: CAA39770.1.
M34710 Genomic DNA. Translation: AAA65584.1.
L29244 Genomic DNA. Translation: AAA22942.1.
L29200 Genomic DNA. Translation: AAB38539.1.
L29234 Genomic DNA. Translation: AAA22944.1.
L29243 Genomic DNA. Translation: AAA22941.1.
X69611 Genomic DNA. Translation: CAA49319.1.
AE000783 Genomic DNA. Translation: AAC66541.1.
Y15090 Genomic DNA. Translation: CAA75365.1.
Y15092 Genomic DNA. Translation: CAA75367.1.
Y15093 Genomic DNA. Translation: CAA75368.1.
PIRiA38450.
A41470. FLLYB3.
I40092.
RefSeqiNP_212281.1. NC_001318.1.
WP_002661938.1. NC_001318.1.

Genome annotation databases

EnsemblBacteriaiAAC66541; AAC66541; BB_0147.
GeneIDi1194982.
KEGGibbu:BB_0147.
PATRICifig|224326.49.peg.546.

Similar proteinsi

Entry informationi

Entry nameiFLA1_BORBU
AccessioniPrimary (citable) accession number: P11089
Secondary accession number(s): O31322, P15295, Q44938
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: June 7, 2017
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families