P11087 (CO1A1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Collagen alpha-1(I) chain

Alternative name(s):
Alpha-1 type I collagen

Gene names

Name:	Col1a1
Synonyms:	Cola1

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1453 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Type I collagen is a member of group I collagen (fibrillar forming collagen).
Subunit structure	Trimers of one alpha 2(I) and two alpha 1(I) chains. Interacts with MRC2 By similarity. Interacts with TRAM2 By similarity.
Subcellular location	Secreted › extracellular space › extracellular matrix By similarity.
Tissue specificity	Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.
Domain	The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function By similarity.
Post-translational modification	Proline residues at the third position of the tripeptide repeating unit (G-X-P) are hydroxylated in some or all of the chains. Proline residues at the second position of the tripeptide repeating unit (G-P-X) are hydroxylated in some of the chains.
Sequence similarities	Belongs to the fibrillar collagen family. Contains 1 fibrillar collagen NC1 domain. Contains 1 VWFC domain.
Sequence caution	The sequence CAA38657.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
Cellular component	Extracellular matrix Secreted
Coding sequence diversity	Alternative splicing
Domain	Collagen Repeat Signal
Ligand	Calcium Metal-binding
PTM	Disulfide bond Glycoprotein Hydroxylation Pyrrolidone carboxylic acid
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	blood vessel development Inferred from mutant phenotype PubMed 14630726. Source: MGI bone trabecula formation Inferred from genetic interaction PubMed 17440987. Source: MGI cartilage development involved in endochondral bone morphogenesis Inferred from mutant phenotype PubMed 18248096. Source: MGI cellular response to amino acid stimulus Inferred from direct assay PubMed 20548288. Source: MGI cellular response to mechanical stimulus Inferred from expression pattern PubMed 21625049. Source: UniProtKB cellular response to retinoic acid Inferred from electronic annotation. Source: Compara cellular response to transforming growth factor beta stimulus Inferred from electronic annotation. Source: Compara collagen biosynthetic process Inferred from electronic annotation. Source: Compara collagen fibril organization Inferred from electronic annotation. Source: Compara embryonic skeletal system development Inferred from electronic annotation. Source: Compara endochondral ossification Inferred from mutant phenotype PubMed 8130375. Source: MGI face morphogenesis Inferred from genetic interaction PubMed 17440987. Source: MGI intramembranous ossification Inferred from genetic interaction PubMed 17440987. Source: MGI negative regulation of cell-substrate adhesion Inferred from direct assay PubMed 17018525. Source: MGI osteoblast differentiation Inferred from expression pattern PubMed 16311053. Source: BHF-UCL positive regulation of canonical Wnt receptor signaling pathway Inferred from electronic annotation. Source: Compara positive regulation of cell migration Inferred from electronic annotation. Source: Compara positive regulation of epithelial to mesenchymal transition Inferred from electronic annotation. Source: Compara positive regulation of transcription, DNA-dependent Inferred from electronic annotation. Source: Compara protein heterotrimerization Inferred from direct assay PubMed 9213002. Source: MGI protein localization to nucleus Inferred from electronic annotation. Source: Compara protein transport Inferred from mutant phenotype PubMed 8906420. Source: MGI response to cAMP Inferred from electronic annotation. Source: Compara response to corticosteroid stimulus Inferred from electronic annotation. Source: Compara response to hydrogen peroxide Inferred from electronic annotation. Source: Compara response to nutrient Inferred from electronic annotation. Source: Compara response to peptide hormone stimulus Inferred from electronic annotation. Source: Compara sensory perception of sound Inferred from electronic annotation. Source: Compara skin development Inferred from mutant phenotype PubMed 18248096. Source: MGI skin morphogenesis Inferred from electronic annotation. Source: Compara tooth mineralization Inferred from electronic annotation. Source: Compara visual perception Inferred from electronic annotation. Source: Compara wound healing Inferred from electronic annotation. Source: Compara
Cellular_component	collagen type I Inferred from direct assay PubMed 8018053. Source: MGI cytoplasm Inferred from direct assay PubMed 8018053. Source: MGI extracellular space Inferred from electronic annotation. Source: Compara
Molecular_function	extracellular matrix structural constituent Inferred from direct assay PubMed 15383546. Source: MGI metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: P11087-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: P11087-2)

The sequence of this isoform differs from the canonical sequence as follows:
     803-1030: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 22	22
	Propeptide	23 – 151	129	N-terminal propeptide		PRO_0000005722
	Chain	152 – 1207	1056	Collagen alpha-1(I) chain		PRO_0000005723
	Propeptide	1208 – 1453	246	C-terminal propeptide		PRO_0000005724
Regions
	Domain	29 – 87	59	VWFC
	Domain	1218 – 1453	236	Fibrillar collagen NC1
	Region	152 – 167	16	Nonhelical region (N-terminal)
	Region	168 – 1181	1014	Triple-helical region
	Region	1182 – 1207	26	Nonhelical region (C-terminal)
	Motif	734 – 736	3	Cell attachment site Potential
	Motif	1082 – 1084	3	Cell attachment site Potential
Sites
	Metal binding	1266	1	Calcium By similarity
	Metal binding	1268	1	Calcium By similarity
	Metal binding	1269	1	Calcium; via carbonyl oxygen By similarity
	Metal binding	1271	1	Calcium; via carbonyl oxygen By similarity
	Metal binding	1274	1	Calcium By similarity
Amino acid modifications
	Modified residue	152	1	Pyrrolidone carboxylic acid By similarity
	Modified residue	160	1	Allysine By similarity
	Modified residue	254	1	5-hydroxylysine; alternate By similarity
	Modified residue	1153	1	3-hydroxyproline By similarity
	Glycosylation	56	1	N-linked (GlcNAc...) Potential
	Glycosylation	254	1	O-linked (Gal...); alternate By similarity
	Glycosylation	1354	1	N-linked (GlcNAc...) Ref.12
	Disulfide bond	1248 ↔ 1280		By similarity
	Disulfide bond	1254		Interchain (with C-1271) By similarity
	Disulfide bond	1271		Interchain (with C-1254) By similarity
	Disulfide bond	1288 ↔ 1451		By similarity
	Disulfide bond	1359 ↔ 1404		By similarity
Natural variations
	Alternative sequence	803 – 1030	228	Missing in isoform 2.		VSP_016548
Experimental info
	Sequence conflict	81	1	E → G in AAA88912. Ref.1
	Sequence conflict	106	1	D → G in AAA88912. Ref.1
	Sequence conflict	136	1	P → H in AAH59281. Ref.3
	Sequence conflict	1202	1	G → D in AAA88912. Ref.1
	Sequence conflict	1219	1	E → A in AAA88912. Ref.1
	Sequence conflict	1222	1	T → A in AAA88912. Ref.1
	Sequence conflict	1335	1	A → T in AAA88912. Ref.1
	Sequence conflict	1399 – 1400	2	TL → RV in AAA88912. Ref.1
	Sequence conflict	1450	1	A → V in CAA29927. Ref.10
	Sequence conflict	1450	1	A → V in CAA33904. Ref.10

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified December 6, 2005. Version 4. Checksum: 0B7F06BBB9A1D5EA	FASTA	1,453	138,032
	10 20 30 40 50 60 MFSFVDLRLL LLLGATALLT HGQEDIPEVS CIHNGLRVPN GETWKPEVCL ICICHNGTAV 70 80 90 100 110 120 CDDVQCNEEL DCPNPQRREG ECCAFCPEEY VSPNSEDVGV EGPKGDPGPQ GPRGPVGPPG 130 140 150 160 170 180 RDGIPGQPGL PGPPGPPGPP GPPGLGGNFA SQMSYGYDEK SAGVSVPGPM GPSGPRGLPG 190 200 210 220 230 240 PPGAPGPQGF QGPPGEPGEP GGSGPMGPRG PPGPPGKNGD DGEAGKPGRP GERGPPGPQG 250 260 270 280 290 300 ARGLPGTAGL PGMKGHRGFS GLDGAKGDAG PAGPKGEPGS PGENGAPGQM GPRGLPGERG 310 320 330 340 350 360 RPGPPGTAGA RGNDGAVGAA GPPGPTGPTG PPGFPGAVGA KGEAGPQGAR GSEGPQGVRG 370 380 390 400 410 420 EPGPPGPAGA AGPAGNPGAD GQPGAKGANG APGIAGAPGF PGARGPSGPQ GPSGPPGPKG 430 440 450 460 470 480 NSGEPGAPGN KGDTGAKGEP GATGVQGPPG PAGEEGKRGA RGEPGPSGLP GPPGERGGPG 490 500 510 520 530 540 SRGFPGADGV AGPKGPSGER GAPGPAGPKG SPGEAGRPGE AGLPGAKGLT GSPGSPGPDG 550 560 570 580 590 600 KTGPPGPAGQ DGRPGPAGPP GARGQAGVMG FPGPKGTAGE PGKAGERGLP GPPGAVGPAG 610 620 630 640 650 660 KDGEAGAQGA PGPAGPAGER GEQGPAGSPG FQGLPGPAGP PGEAGKPGEQ GVPGDLGAPG 670 680 690 700 710 720 PSGARGERGF PGERGVQGPP GPAGPRGNNG APGNDGAKGD TGAPGAPGSQ GAPGLQGMPG 730 740 750 760 770 780 ERGAAGLPGP KGDRGDAGPK GADGSPGKDG ARGLTGPIGP PGPAGAPGDK GEAGPSGPPG 790 800 810 820 830 840 PTGARGAPGD RGEAGPPGPA GFAGPPGADG QPGAKGEPGD TGVKGDAGPP GPAGPAGPPG 850 860 870 880 890 900 PIGNVGAPGP KGPRGAAGPP GATGFPGAAG RVGPPGPSGN AGPPGPPGPV GKEGGKGPRG 910 920 930 940 950 960 ETGPAGRPGE VGPPGPPGPA GEKGSPGADG PAGSPGTPGP QGIAGQRGVV GLPGQRGERG 970 980 990 1000 1010 1020 FPGLPGPSGE PGKQGPSGSS GERGPPGPMG PPGLAGPPGE SGREGSPGAE GSPGRDGAPG 1030 1040 1050 1060 1070 1080 AKGDRGETGP AGPPGAPGAP GAPGPVGPAG KNGDRGETGP AGPAGPIGPA GARGPAGPQG 1090 1100 1110 1120 1130 1140 PRGDKGETGE QGDRGIKGHR GFSGLQGPPG SPGSPGEQGP SGASGPAGPR GPPGSAGSPG 1150 1160 1170 1180 1190 1200 KDGLNGLPGP IGPPGPRGRT GDSGPAGPPG PPGPPGPPGP PSGGYDFSFL PQPPQEKSQD 1210 1220 1230 1240 1250 1260 GGRYYRADDA NVVRDRDLEV DTTLKSLSQQ IENIRSPEGS RKNPARTCRD LKMCHSDWKS 1270 1280 1290 1300 1310 1320 GEYWIDPNQG CNLDAIKVYC NMETGQTCVF PTQPSVPQKN WYISPNPKEK KHVWFGESMT 1330 1340 1350 1360 1370 1380 DGFPFEYGSE GSDPADVAIQ LTFLRLMSTE ASQNITYHCK NSVAYMDQQT GNLKKALLLQ 1390 1400 1410 1420 1430 1440 GSNEIELRGE GNSRFTYSTL VDGCTSHTGT WGKTVIEYKT TKTSRLPIID VAPLDIGAPD 1450 QEFGLDIGPA CFV
	Isoform 2 [UniParc]. Checksum: 5EBF34F79AD32E86	FASTA	1,225	117,820
	10 20 30 40 50 60 MFSFVDLRLL LLLGATALLT HGQEDIPEVS CIHNGLRVPN GETWKPEVCL ICICHNGTAV 70 80 90 100 110 120 CDDVQCNEEL DCPNPQRREG ECCAFCPEEY VSPNSEDVGV EGPKGDPGPQ GPRGPVGPPG 130 140 150 160 170 180 RDGIPGQPGL PGPPGPPGPP GPPGLGGNFA SQMSYGYDEK SAGVSVPGPM GPSGPRGLPG 190 200 210 220 230 240 PPGAPGPQGF QGPPGEPGEP GGSGPMGPRG PPGPPGKNGD DGEAGKPGRP GERGPPGPQG 250 260 270 280 290 300 ARGLPGTAGL PGMKGHRGFS GLDGAKGDAG PAGPKGEPGS PGENGAPGQM GPRGLPGERG 310 320 330 340 350 360 RPGPPGTAGA RGNDGAVGAA GPPGPTGPTG PPGFPGAVGA KGEAGPQGAR GSEGPQGVRG 370 380 390 400 410 420 EPGPPGPAGA AGPAGNPGAD GQPGAKGANG APGIAGAPGF PGARGPSGPQ GPSGPPGPKG 430 440 450 460 470 480 NSGEPGAPGN KGDTGAKGEP GATGVQGPPG PAGEEGKRGA RGEPGPSGLP GPPGERGGPG 490 500 510 520 530 540 SRGFPGADGV AGPKGPSGER GAPGPAGPKG SPGEAGRPGE AGLPGAKGLT GSPGSPGPDG 550 560 570 580 590 600 KTGPPGPAGQ DGRPGPAGPP GARGQAGVMG FPGPKGTAGE PGKAGERGLP GPPGAVGPAG 610 620 630 640 650 660 KDGEAGAQGA PGPAGPAGER GEQGPAGSPG FQGLPGPAGP PGEAGKPGEQ GVPGDLGAPG 670 680 690 700 710 720 PSGARGERGF PGERGVQGPP GPAGPRGNNG APGNDGAKGD TGAPGAPGSQ GAPGLQGMPG 730 740 750 760 770 780 ERGAAGLPGP KGDRGDAGPK GADGSPGKDG ARGLTGPIGP PGPAGAPGDK GEAGPSGPPG 790 800 810 820 830 840 PTGARGAPGD RGEAGPPGPA GFAGPPGAPG APGAPGPVGP AGKNGDRGET GPAGPAGPIG 850 860 870 880 890 900 PAGARGPAGP QGPRGDKGET GEQGDRGIKG HRGFSGLQGP PGSPGSPGEQ GPSGASGPAG 910 920 930 940 950 960 PRGPPGSAGS PGKDGLNGLP GPIGPPGPRG RTGDSGPAGP PGPPGPPGPP GPPSGGYDFS 970 980 990 1000 1010 1020 FLPQPPQEKS QDGGRYYRAD DANVVRDRDL EVDTTLKSLS QQIENIRSPE GSRKNPARTC 1030 1040 1050 1060 1070 1080 RDLKMCHSDW KSGEYWIDPN QGCNLDAIKV YCNMETGQTC VFPTQPSVPQ KNWYISPNPK 1090 1100 1110 1120 1130 1140 EKKHVWFGES MTDGFPFEYG SEGSDPADVA IQLTFLRLMS TEASQNITYH CKNSVAYMDQ 1150 1160 1170 1180 1190 1200 QTGNLKKALL LQGSNEIELR GEGNSRFTYS TLVDGCTSHT GTWGKTVIEY KTTKTSRLPI 1210 1220 IDVAPLDIGA PDQEFGLDIG PACFV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The complete cDNA coding sequence for the mouse pro alpha 1(I) chain of type I procollagen." Li S.W., Khillan J., Prockop D.J. Matrix Biol. 14:593-595(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Strain: FVB/N.
[2]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J.
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2). Strain: FVB/N. Tissue: Colon.
[4]	"Insertion of retrovirus into the first intron of alpha1(I) collagen gene leads to embryonic lethal mutation in mice." Harbers K., Kuehn M., Delius H., Jaenisch R. Proc. Natl. Acad. Sci. U.S.A. 81:1504-1508(1984) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-25.
[5]	"Genomic sequence of mouse COL1A1 encoding the collagen propeptides." Fenton S.P., Lamande S.R., Hannagan M., Stacey A., Jaenisch R., Bateman J.F. Biochim. Biophys. Acta 1216:469-474(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-185 AND 1030-1453.
[6]	"DNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism." Rhodes K., Rippe R.A., Umezawa A., Nehls M., Brenner D.A., Breindl M. Mol. Cell. Biol. 14:5950-5960(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-942. Strain: C57BL/6. Tissue: Liver.
[7]	"Nucleotide sequence of a cDNA clone for mouse pro alpha 1(I) collagen protein." French B.T., Lee W.-H., Maul G.G. Gene 39:311-312(1985) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 518-1128 (ISOFORM 1).
[8]	"DNA sequence analysis of a mouse pro alpha 1 (I) procollagen gene: evidence for a mouse B1 element within the gene." Monson J.M., Friedman J., McCarthy B.J. Mol. Cell. Biol. 2:1362-1371(1982) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 735-1130.
[9]	"Identification of a Balb/c mouse pro alpha 1(I) procollagen gene: evidence for insertions or deletions in gene coding sequences." Monson J.M., McCarthy B.J. DNA 1:59-69(1981) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 735-878 AND 1005-1058.
[10]	"Two mRNAs of mouse pro alpha 1(I) collagen gene differ in the size of the 3'-untranslated region." Mooslehner K., Harbers K. Nucleic Acids Res. 16:773-773(1988) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1442-1453.
[11]	"Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs." Metsaeranta M., Toman D., de Crombrugghe B., Vuorio E. Biochim. Biophys. Acta 1089:241-243(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1442-1453.
[12]	"Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides." Bernhard O.K., Kapp E.A., Simpson R.J. J. Proteome Res. 6:987-995(2007) [PubMed] [Europe PMC] [Abstract] Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1354, MASS SPECTROMETRY. Strain: C57BL/6. Tissue: Plasma.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U08020 mRNA. Translation: AAA88912.1. AL662790, AL606480 Genomic DNA. Translation: CAI25880.1. AL606480, AL662790 Genomic DNA. Translation: CAI23970.1. BC050014 mRNA. Translation: AAH50014.1. BC059281 mRNA. Translation: AAH59281.1. K01688 Genomic DNA. Translation: AAA37330.1. S67530 Genomic DNA. Translation: AAB29424.1. S67482 Genomic DNA. No translation available. X54876 Genomic DNA. Translation: CAA38657.1. Sequence problems. M14423 mRNA. Translation: AAA37333.1. M17491 Genomic DNA. Translation: AAA37334.1. K03036 , K03029, K03030, K03031, K03032, K03033, K03034, K03035 Genomic DNA. Translation: AAA37332.1. X06753 Genomic DNA. Translation: CAA29927.1. X15896 Genomic DNA. Translation: CAA33904.1. X57981 Genomic DNA. Translation: CAA41046.1.
IPI	IPI00329872. IPI00623191.
PIR	I49558. S21626. S57243.
RefSeq	NP_031768.2. NM_007742.3.
UniGene	Mm.277735. Mm.458212.
3D structure databases
ProteinModelPortal	P11087.
SMR	P11087. Positions 30-89, 1236-1453.
ModBase	Search...
Protein-protein interaction databases
IntAct	P11087. 1 interaction.
STRING	10090.ENSMUSP00000001547.
PTM databases
PhosphoSite	P11087.
Proteomic databases
PaxDb	P11087.
PRIDE	P11087.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000001547; ENSMUSP00000001547; ENSMUSG00000001506.
GeneID	12842.
KEGG	mmu:12842.
UCSC	uc007kzn.1. mouse.
Organism-specific databases
CTD	1277.
MGI	MGI:88467. Col1a1.
Phylogenomic databases
eggNOG	NOG12793.
GeneTree	ENSGT00660000095287.
HOVERGEN	HBG004933.
InParanoid	P11087.
KO	K06236.
OMA	VAYMDQQ.
OrthoDB	EOG4S4PHP.
Gene expression databases
ArrayExpress	P11087.
Bgee	P11087.
CleanEx	MM_COL1A1.
Genevestigator	P11087.
GermOnline	ENSMUSG00000001506. Mus musculus.
Family and domain databases
InterPro	IPR008160. Collagen. IPR000885. Fib_collagen_C. IPR001007. VWF_C. [Graphical view]
Pfam	PF01410. COLFI. 1 hit. PF01391. Collagen. 9 hits. PF00093. VWC. 1 hit. [Graphical view]
ProDom	PD002078. Fib_collagen_C. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00038. COLFI. 1 hit. SM00214. VWC. 1 hit. [Graphical view]
PROSITE	PS51461. NC1_FIB. 1 hit. PS01208. VWFC_1. 1 hit. PS50184. VWFC_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	COL1A1. mouse.
NextBio	282376.
PMAP-CutDB	P11087.
SOURCE	Search...

Entry information

Entry name

CO1A1_MOUSE

Accession

Primary (citable) accession number: P11087
Secondary accession number(s): Q53WT0 , Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
Last sequence update:	December 6, 2005
Last modified:	May 1, 2013
This is version 136 of the entry and version 4 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program