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P11087

- CO1A1_MOUSE

UniProt

P11087 - CO1A1_MOUSE

Protein

Collagen alpha-1(I) chain

Gene

Col1a1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 150 (01 Oct 2014)
      Sequence version 4 (06 Dec 2005)
      Previous versions | rss
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    Functioni

    Type I collagen is a member of group I collagen (fibrillar forming collagen).

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi1266 – 12661CalciumBy similarity
    Metal bindingi1268 – 12681CalciumBy similarity
    Metal bindingi1269 – 12691Calcium; via carbonyl oxygenBy similarity
    Metal bindingi1271 – 12711Calcium; via carbonyl oxygenBy similarity
    Metal bindingi1274 – 12741CalciumBy similarity

    GO - Molecular functioni

    1. extracellular matrix structural constituent Source: MGI
    2. metal ion binding Source: UniProtKB-KW
    3. protein binding Source: MGI

    GO - Biological processi

    1. blood vessel development Source: MGI
    2. bone trabecula formation Source: MGI
    3. cartilage development involved in endochondral bone morphogenesis Source: MGI
    4. cellular response to amino acid stimulus Source: MGI
    5. cellular response to mechanical stimulus Source: UniProtKB
    6. cellular response to retinoic acid Source: Ensembl
    7. cellular response to transforming growth factor beta stimulus Source: Ensembl
    8. collagen biosynthetic process Source: Ensembl
    9. collagen fibril organization Source: Ensembl
    10. embryonic skeletal system development Source: Ensembl
    11. endochondral ossification Source: MGI
    12. face morphogenesis Source: MGI
    13. intramembranous ossification Source: MGI
    14. negative regulation of cell-substrate adhesion Source: MGI
    15. osteoblast differentiation Source: BHF-UCL
    16. positive regulation of canonical Wnt signaling pathway Source: Ensembl
    17. positive regulation of cell migration Source: Ensembl
    18. positive regulation of epithelial to mesenchymal transition Source: Ensembl
    19. positive regulation of transcription, DNA-templated Source: Ensembl
    20. protein heterotrimerization Source: MGI
    21. protein localization to nucleus Source: Ensembl
    22. protein transport Source: MGI
    23. response to cAMP Source: Ensembl
    24. response to corticosteroid Source: Ensembl
    25. response to estradiol Source: Ensembl
    26. response to hydrogen peroxide Source: Ensembl
    27. response to nutrient Source: Ensembl
    28. response to peptide hormone Source: Ensembl
    29. sensory perception of sound Source: Ensembl
    30. skeletal system development Source: MGI
    31. skeletal system morphogenesis Source: MGI
    32. skin development Source: MGI
    33. skin morphogenesis Source: Ensembl
    34. tooth mineralization Source: Ensembl
    35. visual perception Source: Ensembl
    36. wound healing Source: Ensembl

    Keywords - Ligandi

    Calcium, Metal-binding

    Enzyme and pathway databases

    ReactomeiREACT_196515. Crosslinking of collagen fibrils.
    REACT_196581. Scavenging by Class A Receptors.
    REACT_196595. Anchoring fibril formation.
    REACT_196606. ECM proteoglycans.
    REACT_196607. Non-integrin membrane-ECM interactions.
    REACT_196644. Syndecan interactions.
    REACT_198984. Collagen biosynthesis and modifying enzymes.
    REACT_199046. Assembly of collagen fibrils and other multimeric structures.
    REACT_199055. Collagen degradation.
    REACT_206066. Extracellular matrix organization.
    REACT_216309. Integrin cell surface interactions.
    REACT_220092. GPVI-mediated activation cascade.
    REACT_225107. Platelet Adhesion to exposed collagen.
    REACT_225233. Cell surface interactions at the vascular wall.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Collagen alpha-1(I) chain
    Alternative name(s):
    Alpha-1 type I collagen
    Gene namesi
    Name:Col1a1
    Synonyms:Cola1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:88467. Col1a1.

    Subcellular locationi

    Secretedextracellular spaceextracellular matrix PROSITE-ProRule annotation

    GO - Cellular componenti

    1. collagen trimer Source: MGI
    2. collagen type I trimer Source: MGI
    3. cytoplasm Source: MGI
    4. extracellular matrix Source: MGI
    5. extracellular space Source: Ensembl
    6. proteinaceous extracellular matrix Source: MGI

    Keywords - Cellular componenti

    Extracellular matrix, Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2222Add
    BLAST
    Propeptidei23 – 151129N-terminal propeptidePRO_0000005722Add
    BLAST
    Chaini152 – 12071056Collagen alpha-1(I) chainPRO_0000005723Add
    BLAST
    Propeptidei1208 – 1453246C-terminal propeptidePRO_0000005724Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi56 – 561N-linked (GlcNAc...)Sequence Analysis
    Modified residuei152 – 1521Pyrrolidone carboxylic acidBy similarity
    Modified residuei160 – 1601AllysineBy similarity
    Modified residuei254 – 25415-hydroxylysine; alternateBy similarity
    Glycosylationi254 – 2541O-linked (Gal...); alternateBy similarity
    Modified residuei1153 – 115313-hydroxyprolineBy similarity
    Disulfide bondi1248 ↔ 1280PROSITE-ProRule annotation
    Disulfide bondi1254 – 1254Interchain (with C-1271)PROSITE-ProRule annotation
    Disulfide bondi1271 – 1271Interchain (with C-1254)PROSITE-ProRule annotation
    Disulfide bondi1288 ↔ 1451PROSITE-ProRule annotation
    Glycosylationi1354 – 13541N-linked (GlcNAc...)1 Publication
    Disulfide bondi1359 ↔ 1404PROSITE-ProRule annotation

    Post-translational modificationi

    Proline residues at the third position of the tripeptide repeating unit (G-X-P) are hydroxylated in some or all of the chains. Proline residues at the second position of the tripeptide repeating unit (G-P-X) are hydroxylated in some of the chains.

    Keywords - PTMi

    Disulfide bond, Glycoprotein, Hydroxylation, Pyrrolidone carboxylic acid

    Proteomic databases

    MaxQBiP11087.
    PaxDbiP11087.
    PRIDEiP11087.

    PTM databases

    PhosphoSiteiP11087.

    Miscellaneous databases

    PMAP-CutDBP11087.

    Expressioni

    Tissue specificityi

    Forms the fibrils of tendon, ligaments and bones. In bones the fibrils are mineralized with calcium hydroxyapatite.

    Gene expression databases

    ArrayExpressiP11087.
    BgeeiP11087.
    CleanExiMM_COL1A1.
    GenevestigatoriP11087.

    Interactioni

    Subunit structurei

    Trimers of one alpha 2(I) and two alpha 1(I) chains. Interacts with MRC2 By similarity. Interacts with TRAM2 By similarity.By similarity

    Protein-protein interaction databases

    BioGridi198831. 7 interactions.
    IntActiP11087. 2 interactions.
    MINTiMINT-4091294.
    STRINGi10090.ENSMUSP00000001547.

    Structurei

    3D structure databases

    ProteinModelPortaliP11087.
    SMRiP11087. Positions 30-89, 1236-1453.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini29 – 8759VWFCPROSITE-ProRule annotationAdd
    BLAST
    Domaini1218 – 1453236Fibrillar collagen NC1PROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni152 – 16716Nonhelical region (N-terminal)Add
    BLAST
    Regioni168 – 11811014Triple-helical regionAdd
    BLAST
    Regioni1182 – 120726Nonhelical region (C-terminal)Add
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi734 – 7363Cell attachment siteSequence Analysis
    Motifi1082 – 10843Cell attachment siteSequence Analysis

    Domaini

    The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function By similarity.By similarity

    Sequence similaritiesi

    Belongs to the fibrillar collagen family.PROSITE-ProRule annotation
    Contains 1 fibrillar collagen NC1 domain.PROSITE-ProRule annotation
    Contains 1 VWFC domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Collagen, Repeat, Signal

    Phylogenomic databases

    eggNOGiNOG12793.
    GeneTreeiENSGT00740000114967.
    HOVERGENiHBG004933.
    InParanoidiP11087.
    KOiK06236.
    OMAiKEKRHVW.
    OrthoDBiEOG7TJ3HH.
    PhylomeDBiP11087.
    TreeFamiTF344135.

    Family and domain databases

    InterProiIPR008160. Collagen.
    IPR000885. Fib_collagen_C.
    IPR001007. VWF_C.
    [Graphical view]
    PfamiPF01410. COLFI. 1 hit.
    PF01391. Collagen. 9 hits.
    PF00093. VWC. 1 hit.
    [Graphical view]
    ProDomiPD002078. Fib_collagen_C. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SMARTiSM00038. COLFI. 1 hit.
    SM00214. VWC. 1 hit.
    [Graphical view]
    PROSITEiPS51461. NC1_FIB. 1 hit.
    PS01208. VWFC_1. 1 hit.
    PS50184. VWFC_2. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: P11087-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MFSFVDLRLL LLLGATALLT HGQEDIPEVS CIHNGLRVPN GETWKPEVCL     50
    ICICHNGTAV CDDVQCNEEL DCPNPQRREG ECCAFCPEEY VSPNSEDVGV 100
    EGPKGDPGPQ GPRGPVGPPG RDGIPGQPGL PGPPGPPGPP GPPGLGGNFA 150
    SQMSYGYDEK SAGVSVPGPM GPSGPRGLPG PPGAPGPQGF QGPPGEPGEP 200
    GGSGPMGPRG PPGPPGKNGD DGEAGKPGRP GERGPPGPQG ARGLPGTAGL 250
    PGMKGHRGFS GLDGAKGDAG PAGPKGEPGS PGENGAPGQM GPRGLPGERG 300
    RPGPPGTAGA RGNDGAVGAA GPPGPTGPTG PPGFPGAVGA KGEAGPQGAR 350
    GSEGPQGVRG EPGPPGPAGA AGPAGNPGAD GQPGAKGANG APGIAGAPGF 400
    PGARGPSGPQ GPSGPPGPKG NSGEPGAPGN KGDTGAKGEP GATGVQGPPG 450
    PAGEEGKRGA RGEPGPSGLP GPPGERGGPG SRGFPGADGV AGPKGPSGER 500
    GAPGPAGPKG SPGEAGRPGE AGLPGAKGLT GSPGSPGPDG KTGPPGPAGQ 550
    DGRPGPAGPP GARGQAGVMG FPGPKGTAGE PGKAGERGLP GPPGAVGPAG 600
    KDGEAGAQGA PGPAGPAGER GEQGPAGSPG FQGLPGPAGP PGEAGKPGEQ 650
    GVPGDLGAPG PSGARGERGF PGERGVQGPP GPAGPRGNNG APGNDGAKGD 700
    TGAPGAPGSQ GAPGLQGMPG ERGAAGLPGP KGDRGDAGPK GADGSPGKDG 750
    ARGLTGPIGP PGPAGAPGDK GEAGPSGPPG PTGARGAPGD RGEAGPPGPA 800
    GFAGPPGADG QPGAKGEPGD TGVKGDAGPP GPAGPAGPPG PIGNVGAPGP 850
    KGPRGAAGPP GATGFPGAAG RVGPPGPSGN AGPPGPPGPV GKEGGKGPRG 900
    ETGPAGRPGE VGPPGPPGPA GEKGSPGADG PAGSPGTPGP QGIAGQRGVV 950
    GLPGQRGERG FPGLPGPSGE PGKQGPSGSS GERGPPGPMG PPGLAGPPGE 1000
    SGREGSPGAE GSPGRDGAPG AKGDRGETGP AGPPGAPGAP GAPGPVGPAG 1050
    KNGDRGETGP AGPAGPIGPA GARGPAGPQG PRGDKGETGE QGDRGIKGHR 1100
    GFSGLQGPPG SPGSPGEQGP SGASGPAGPR GPPGSAGSPG KDGLNGLPGP 1150
    IGPPGPRGRT GDSGPAGPPG PPGPPGPPGP PSGGYDFSFL PQPPQEKSQD 1200
    GGRYYRADDA NVVRDRDLEV DTTLKSLSQQ IENIRSPEGS RKNPARTCRD 1250
    LKMCHSDWKS GEYWIDPNQG CNLDAIKVYC NMETGQTCVF PTQPSVPQKN 1300
    WYISPNPKEK KHVWFGESMT DGFPFEYGSE GSDPADVAIQ LTFLRLMSTE 1350
    ASQNITYHCK NSVAYMDQQT GNLKKALLLQ GSNEIELRGE GNSRFTYSTL 1400
    VDGCTSHTGT WGKTVIEYKT TKTSRLPIID VAPLDIGAPD QEFGLDIGPA 1450
    CFV 1453
    Length:1,453
    Mass (Da):138,032
    Last modified:December 6, 2005 - v4
    Checksum:i0B7F06BBB9A1D5EA
    GO
    Isoform 2 (identifier: P11087-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         803-1030: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:1,225
    Mass (Da):117,820
    Checksum:i5EBF34F79AD32E86
    GO

    Sequence cautioni

    The sequence CAA38657.1 differs from that shown. Reason: Erroneous gene model prediction.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti81 – 811E → G in AAA88912. (PubMed:8535610)Curated
    Sequence conflicti106 – 1061D → G in AAA88912. (PubMed:8535610)Curated
    Sequence conflicti136 – 1361P → H in AAH59281. (PubMed:15489334)Curated
    Sequence conflicti1202 – 12021G → D in AAA88912. (PubMed:8535610)Curated
    Sequence conflicti1219 – 12191E → A in AAA88912. (PubMed:8535610)Curated
    Sequence conflicti1222 – 12221T → A in AAA88912. (PubMed:8535610)Curated
    Sequence conflicti1335 – 13351A → T in AAA88912. (PubMed:8535610)Curated
    Sequence conflicti1399 – 14002TL → RV in AAA88912. (PubMed:8535610)Curated
    Sequence conflicti1450 – 14501A → V in CAA29927. (PubMed:3340560)Curated
    Sequence conflicti1450 – 14501A → V in CAA33904. (PubMed:3340560)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei803 – 1030228Missing in isoform 2. 1 PublicationVSP_016548Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U08020 mRNA. Translation: AAA88912.1.
    AL662790, AL606480 Genomic DNA. Translation: CAI25880.1.
    AL606480, AL662790 Genomic DNA. Translation: CAI23970.1.
    BC050014 mRNA. Translation: AAH50014.1.
    BC059281 mRNA. Translation: AAH59281.1.
    K01688 Genomic DNA. Translation: AAA37330.1.
    S67530 Genomic DNA. Translation: AAB29424.1.
    S67482 Genomic DNA. No translation available.
    X54876 Genomic DNA. Translation: CAA38657.1. Sequence problems.
    M14423 mRNA. Translation: AAA37333.1.
    M17491 Genomic DNA. Translation: AAA37334.1.
    K03036
    , K03029, K03030, K03031, K03032, K03033, K03034, K03035 Genomic DNA. Translation: AAA37332.1.
    X06753 Genomic DNA. Translation: CAA29927.1.
    X15896 Genomic DNA. Translation: CAA33904.1.
    X57981 Genomic DNA. Translation: CAA41046.1.
    CCDSiCCDS25265.1. [P11087-1]
    PIRiI49558.
    S57243. S21626.
    RefSeqiNP_031768.2. NM_007742.3. [P11087-1]
    UniGeneiMm.277735.
    Mm.458212.

    Genome annotation databases

    EnsembliENSMUST00000001547; ENSMUSP00000001547; ENSMUSG00000001506. [P11087-1]
    GeneIDi12842.
    KEGGimmu:12842.
    UCSCiuc007kzn.1. mouse. [P11087-1]

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U08020 mRNA. Translation: AAA88912.1 .
    AL662790 , AL606480 Genomic DNA. Translation: CAI25880.1 .
    AL606480 , AL662790 Genomic DNA. Translation: CAI23970.1 .
    BC050014 mRNA. Translation: AAH50014.1 .
    BC059281 mRNA. Translation: AAH59281.1 .
    K01688 Genomic DNA. Translation: AAA37330.1 .
    S67530 Genomic DNA. Translation: AAB29424.1 .
    S67482 Genomic DNA. No translation available.
    X54876 Genomic DNA. Translation: CAA38657.1 . Sequence problems.
    M14423 mRNA. Translation: AAA37333.1 .
    M17491 Genomic DNA. Translation: AAA37334.1 .
    K03036
    , K03029 , K03030 , K03031 , K03032 , K03033 , K03034 , K03035 Genomic DNA. Translation: AAA37332.1 .
    X06753 Genomic DNA. Translation: CAA29927.1 .
    X15896 Genomic DNA. Translation: CAA33904.1 .
    X57981 Genomic DNA. Translation: CAA41046.1 .
    CCDSi CCDS25265.1. [P11087-1 ]
    PIRi I49558.
    S57243. S21626.
    RefSeqi NP_031768.2. NM_007742.3. [P11087-1 ]
    UniGenei Mm.277735.
    Mm.458212.

    3D structure databases

    ProteinModelPortali P11087.
    SMRi P11087. Positions 30-89, 1236-1453.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 198831. 7 interactions.
    IntActi P11087. 2 interactions.
    MINTi MINT-4091294.
    STRINGi 10090.ENSMUSP00000001547.

    PTM databases

    PhosphoSitei P11087.

    Proteomic databases

    MaxQBi P11087.
    PaxDbi P11087.
    PRIDEi P11087.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000001547 ; ENSMUSP00000001547 ; ENSMUSG00000001506 . [P11087-1 ]
    GeneIDi 12842.
    KEGGi mmu:12842.
    UCSCi uc007kzn.1. mouse. [P11087-1 ]

    Organism-specific databases

    CTDi 1277.
    MGIi MGI:88467. Col1a1.

    Phylogenomic databases

    eggNOGi NOG12793.
    GeneTreei ENSGT00740000114967.
    HOVERGENi HBG004933.
    InParanoidi P11087.
    KOi K06236.
    OMAi KEKRHVW.
    OrthoDBi EOG7TJ3HH.
    PhylomeDBi P11087.
    TreeFami TF344135.

    Enzyme and pathway databases

    Reactomei REACT_196515. Crosslinking of collagen fibrils.
    REACT_196581. Scavenging by Class A Receptors.
    REACT_196595. Anchoring fibril formation.
    REACT_196606. ECM proteoglycans.
    REACT_196607. Non-integrin membrane-ECM interactions.
    REACT_196644. Syndecan interactions.
    REACT_198984. Collagen biosynthesis and modifying enzymes.
    REACT_199046. Assembly of collagen fibrils and other multimeric structures.
    REACT_199055. Collagen degradation.
    REACT_206066. Extracellular matrix organization.
    REACT_216309. Integrin cell surface interactions.
    REACT_220092. GPVI-mediated activation cascade.
    REACT_225107. Platelet Adhesion to exposed collagen.
    REACT_225233. Cell surface interactions at the vascular wall.

    Miscellaneous databases

    ChiTaRSi COL1A1. mouse.
    NextBioi 282376.
    PMAP-CutDB P11087.
    PROi P11087.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P11087.
    Bgeei P11087.
    CleanExi MM_COL1A1.
    Genevestigatori P11087.

    Family and domain databases

    InterProi IPR008160. Collagen.
    IPR000885. Fib_collagen_C.
    IPR001007. VWF_C.
    [Graphical view ]
    Pfami PF01410. COLFI. 1 hit.
    PF01391. Collagen. 9 hits.
    PF00093. VWC. 1 hit.
    [Graphical view ]
    ProDomi PD002078. Fib_collagen_C. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SMARTi SM00038. COLFI. 1 hit.
    SM00214. VWC. 1 hit.
    [Graphical view ]
    PROSITEi PS51461. NC1_FIB. 1 hit.
    PS01208. VWFC_1. 1 hit.
    PS50184. VWFC_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete cDNA coding sequence for the mouse pro alpha 1(I) chain of type I procollagen."
      Li S.W., Khillan J., Prockop D.J.
      Matrix Biol. 14:593-595(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Strain: FVB/N.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Strain: FVB/N.
      Tissue: Colon.
    4. "Insertion of retrovirus into the first intron of alpha1(I) collagen gene leads to embryonic lethal mutation in mice."
      Harbers K., Kuehn M., Delius H., Jaenisch R.
      Proc. Natl. Acad. Sci. U.S.A. 81:1504-1508(1984) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-25.
    5. "Genomic sequence of mouse COL1A1 encoding the collagen propeptides."
      Fenton S.P., Lamande S.R., Hannagan M., Stacey A., Jaenisch R., Bateman J.F.
      Biochim. Biophys. Acta 1216:469-474(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-185 AND 1030-1453.
    6. "DNA methylation represses the murine alpha 1(I) collagen promoter by an indirect mechanism."
      Rhodes K., Rippe R.A., Umezawa A., Nehls M., Brenner D.A., Breindl M.
      Mol. Cell. Biol. 14:5950-5960(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-942.
      Strain: C57BL/6.
      Tissue: Liver.
    7. "Nucleotide sequence of a cDNA clone for mouse pro alpha 1(I) collagen protein."
      French B.T., Lee W.-H., Maul G.G.
      Gene 39:311-312(1985) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 518-1128 (ISOFORM 1).
    8. "DNA sequence analysis of a mouse pro alpha 1 (I) procollagen gene: evidence for a mouse B1 element within the gene."
      Monson J.M., Friedman J., McCarthy B.J.
      Mol. Cell. Biol. 2:1362-1371(1982) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 735-1130.
    9. "Identification of a Balb/c mouse pro alpha 1(I) procollagen gene: evidence for insertions or deletions in gene coding sequences."
      Monson J.M., McCarthy B.J.
      DNA 1:59-69(1981) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 735-878 AND 1005-1058.
    10. "Two mRNAs of mouse pro alpha 1(I) collagen gene differ in the size of the 3'-untranslated region."
      Mooslehner K., Harbers K.
      Nucleic Acids Res. 16:773-773(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1442-1453.
    11. "Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs."
      Metsaeranta M., Toman D., de Crombrugghe B., Vuorio E.
      Biochim. Biophys. Acta 1089:241-243(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1442-1453.
    12. "Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides."
      Bernhard O.K., Kapp E.A., Simpson R.J.
      J. Proteome Res. 6:987-995(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1354.
      Strain: C57BL/6.
      Tissue: Plasma.

    Entry informationi

    Entry nameiCO1A1_MOUSE
    AccessioniPrimary (citable) accession number: P11087
    Secondary accession number(s): Q53WT0
    , Q60635, Q61367, Q61427, Q63919, Q6PCL3, Q810J9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1989
    Last sequence update: December 6, 2005
    Last modified: October 1, 2014
    This is version 150 of the entry and version 4 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3