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Protein

Ferredoxin, heterocyst

Gene

fdxH

Organism
Nostoc sp. (strain PCC 7120 / UTEX 2576)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. Donates electrons to the nitrogenase.

Cofactori

[2Fe-2S] clusterNote: Binds 1 [2Fe-2S] cluster.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi42 – 421Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation1 Publication
Metal bindingi47 – 471Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation1 Publication
Metal bindingi50 – 501Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation1 Publication
Metal bindingi80 – 801Iron-sulfur (2Fe-2S)PROSITE-ProRule annotation1 Publication

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Electron transport, Nitrogen fixation, Transport

Keywords - Ligandi

2Fe-2S, Iron, Iron-sulfur, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ferredoxin, heterocyst
Gene namesi
Name:fdxH
Ordered Locus Names:all1430
OrganismiNostoc sp. (strain PCC 7120 / UTEX 2576)
Taxonomic identifieri103690 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeNostoc
Proteomesi
  • UP000002483 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved
Chaini2 – 9998Ferredoxin, heterocystPRO_0000189301Add
BLAST

Expressioni

Keywords - Developmental stagei

Heterocyst

Interactioni

Protein-protein interaction databases

STRINGi103690.all1430.

Structurei

Secondary structure

1
99
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 108Combined sources
Turni11 – 144Combined sources
Beta strandi15 – 228Combined sources
Helixi27 – 337Combined sources
Beta strandi41 – 488Combined sources
Beta strandi51 – 577Combined sources
Helixi69 – 735Combined sources
Beta strandi76 – 783Combined sources
Helixi79 – 813Combined sources
Beta strandi83 – 919Combined sources
Helixi95 – 973Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1FRDX-ray1.70A2-99[»]
ProteinModelPortaliP11053.
SMRiP11053. Positions 2-99.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP11053.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 96932Fe-2S ferredoxin-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the 2Fe2S plant-type ferredoxin family.Curated
Contains 1 2Fe-2S ferredoxin-type domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0633. LUCA.
HOGENOMiHOG000217152.
OMAiNCTIKTH.
OrthoDBiEOG6GJC0W.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR001041. 2Fe-2S_ferredoxin-type.
IPR006058. 2Fe2S_fd_BS.
IPR012675. Beta-grasp_dom.
IPR010241. Fd_pln.
[Graphical view]
PfamiPF00111. Fer2. 1 hit.
[Graphical view]
SUPFAMiSSF54292. SSF54292. 1 hit.
TIGRFAMsiTIGR02008. fdx_plant. 1 hit.
PROSITEiPS00197. 2FE2S_FER_1. 1 hit.
PS51085. 2FE2S_FER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P11053-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASYQVRLIN KKQDIDTTIE IDEETTILDG AEENGIELPF SCHSGSCSSC
60 70 80 90
VGKVVEGEVD QSDQIFLDDE QMGKGFALLC VTYPRSNCTI KTHQEPYLA
Length:99
Mass (Da):10,949
Last modified:January 23, 2007 - v3
Checksum:iE47E1A32437A4D03
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13522 Genomic DNA. Translation: CAA31873.1.
BA000019 Genomic DNA. Translation: BAB73387.1.
PIRiAC1985.
S04543.
RefSeqiWP_010995602.1. NC_003272.1.

Genome annotation databases

EnsemblBacteriaiBAB73387; BAB73387; BAB73387.
KEGGiana:all1430.
PATRICi22772852. VBINosSp37423_1909.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13522 Genomic DNA. Translation: CAA31873.1.
BA000019 Genomic DNA. Translation: BAB73387.1.
PIRiAC1985.
S04543.
RefSeqiWP_010995602.1. NC_003272.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1FRDX-ray1.70A2-99[»]
ProteinModelPortaliP11053.
SMRiP11053. Positions 2-99.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi103690.all1430.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB73387; BAB73387; BAB73387.
KEGGiana:all1430.
PATRICi22772852. VBINosSp37423_1909.

Phylogenomic databases

eggNOGiCOG0633. LUCA.
HOGENOMiHOG000217152.
OMAiNCTIKTH.
OrthoDBiEOG6GJC0W.

Miscellaneous databases

EvolutionaryTraceiP11053.

Family and domain databases

Gene3Di3.10.20.30. 1 hit.
InterProiIPR001041. 2Fe-2S_ferredoxin-type.
IPR006058. 2Fe2S_fd_BS.
IPR012675. Beta-grasp_dom.
IPR010241. Fd_pln.
[Graphical view]
PfamiPF00111. Fer2. 1 hit.
[Graphical view]
SUPFAMiSSF54292. SSF54292. 1 hit.
TIGRFAMsiTIGR02008. fdx_plant. 1 hit.
PROSITEiPS00197. 2FE2S_FER_1. 1 hit.
PS51085. 2FE2S_FER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning and nucleotide sequence analysis of the gene coding for heterocyst ferredoxin from the cyanobacterium Anabaena sp. strain PCC 7120."
    Boehme H., Haselkorn R.
    Mol. Gen. Genet. 214:278-285(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 7120 / UTEX 2576.
  3. "Molecular structure of the oxidized, recombinant, heterocyst [2Fe-2S] ferredoxin from Anabaena 7120 determined to 1.7-A resolution."
    Jacobson B.L., Chae Y.K., Markley J.L., Rayment I., Holden H.M.
    Biochemistry 32:6788-6793(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.7 ANGSTROMS).

Entry informationi

Entry nameiFERH_NOSS1
AccessioniPrimary (citable) accession number: P11053
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: January 23, 2007
Last modified: December 9, 2015
This is version 118 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

This ferredoxin is expressed by heterocysts and differs from the ferredoxin expressed in vegetative cells.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.