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P10930

- FIB12_BPT4

UniProt

P10930 - FIB12_BPT4

Protein

Short tail fiber protein gp12

Gene

12

Organism
Enterobacteria phage T4 (Bacteriophage T4)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 99 (01 Oct 2014)
      Sequence version 3 (05 May 2009)
      Previous versions | rss
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    Functioni

    Structural component of the short tail fiber. Secondary adhesin that binds irreversibly to the lipopolysaccharides component on the cell surface of Escherichia coli B strains during virus attachment.1 Publication

    GO - Molecular functioni

    1. metal ion binding Source: InterPro

    GO - Biological processi

    1. viral entry into host cell Source: UniProtKB-KW
    2. virion attachment to host cell Source: UniProtKB-KW

    Keywords - Biological processi

    Host-virus interaction, Viral attachment to host cell, Virus entry into host cell

    Protein family/group databases

    TCDBi1.K.1.1.1. the gp27/5 t4-baseplate (t4-bp) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Short tail fiber protein gp12
    Alternative name(s):
    Gene product 12
    Short name:
    gp12
    Gene namesi
    Name:12
    OrganismiEnterobacteria phage T4 (Bacteriophage T4)
    Taxonomic identifieri10665 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeTevenvirinaeT4likevirus
    Virus hostiEscherichia coli [TaxID: 562]
    ProteomesiUP000009087: Genome

    Subcellular locationi

    GO - Cellular componenti

    1. virion Source: CACAO

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 527527Short tail fiber protein gp12PRO_0000165002Add
    BLAST

    Proteomic databases

    PRIDEiP10930.

    Interactioni

    Subunit structurei

    Homotrimer.

    Structurei

    Secondary structure

    1
    527
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi247 – 2504
    Beta strandi257 – 2593
    Beta strandi264 – 2685
    Beta strandi276 – 2816
    Helixi335 – 3406
    Beta strandi346 – 3538
    Beta strandi359 – 3646
    Turni369 – 3713
    Helixi373 – 3786
    Turni379 – 3835
    Beta strandi387 – 3915
    Helixi407 – 4104
    Helixi412 – 4143
    Beta strandi415 – 4173
    Turni425 – 4284
    Beta strandi454 – 4563
    Beta strandi465 – 4673
    Helixi493 – 4953
    Helixi498 – 5003
    Beta strandi508 – 5103
    Beta strandi520 – 5245

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1H6WX-ray1.90A85-396[»]
    B518-527[»]
    1OCYX-ray1.50A332-527[»]
    1PDIelectron microscopy12.00A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R250-527[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP10930.

    Family & Domainsi

    Family and domain databases

    Gene3Di2.160.30.10. 1 hit.
    3.90.1340.10. 1 hit.
    4.10.1070.10. 1 hit.
    InterProiIPR015173. Phage_T4_Gp12.
    IPR023304. Phage_T4_Gp12_dom2.
    IPR011083. Phage_tail_collar_dom.
    IPR027448. Short_tail_fibre_C.
    [Graphical view]
    PfamiPF07484. Collar. 1 hit.
    PF09089. gp12-short_mid. 1 hit.
    PF14928. S_tail_recep_bd. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P10930-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNNTYQHVS NESRYVKFDP TDTNFPPEIT DVQAAIAAIS PAGVNGVPDA    50
    SSTTKGILFI PTEQEVIDGT NNTKAVTPAT LATRLSYPNA TETVYGLTRY 100
    STNDEAIAGV NNESSITPAK FTVALNNAFE TRVSTESSNG VIKISSLPQA 150
    LAGADDTTAM TPLKTQQLAI KLIAQIAPSE TTATESDQGV VQLATVAQVR 200
    QGTLREGYAI SPYTFMNSSS TEEYKGVIKL GTQSEVNSNN ASVAVTGATL 250
    NGRGSTTSMR GVVKLTTTAG SQSGGDASSA LAWNADVIQQ RGGQIIYGTL 300
    RIEDTFTIAN GGANITGTVR MTGGYIQGNR IVTQNEIDRT IPVGAIMMWA 350
    ADSLPSDAWR FCHGGTVSAS DCPLYASRIG TRYGGNPSNP GLPDMRGLFV 400
    RGSGRGSHLT NPNVNGNDQF GKPRLGVGCT GGYVGEVQIQ QMSYHKHAGG 450
    FGEHDDLGAF GNTRRSNFVG TRKGLDWDNR SYFTNDGYEI DPESQRNSKY 500
    TLNRPELIGN ETRPWNISLN YIIKVKE 527
    Length:527
    Mass (Da):56,205
    Last modified:May 5, 2009 - v3
    Checksum:iF86C7E65205486CC
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti33 – 331Q → H in CAA29951. (PubMed:3357780)Curated
    Sequence conflicti33 – 331Q → H in AAD42417. (PubMed:12626685)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X06792 Genomic DNA. Translation: CAA29951.1.
    AF158101 Genomic DNA. Translation: AAD42417.1.
    M26253 Genomic DNA. Translation: AAA32495.1.
    X14192 Genomic DNA. Translation: CAA32398.1.
    PIRiC32479.
    S01889. GIBPT4.
    RefSeqiNP_049770.1. NC_000866.4.

    Genome annotation databases

    GeneIDi1258789.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X06792 Genomic DNA. Translation: CAA29951.1 .
    AF158101 Genomic DNA. Translation: AAD42417.1 .
    M26253 Genomic DNA. Translation: AAA32495.1 .
    X14192 Genomic DNA. Translation: CAA32398.1 .
    PIRi C32479.
    S01889. GIBPT4.
    RefSeqi NP_049770.1. NC_000866.4.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1H6W X-ray 1.90 A 85-396 [» ]
    B 518-527 [» ]
    1OCY X-ray 1.50 A 332-527 [» ]
    1PDI electron microscopy 12.00 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R 250-527 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    TCDBi 1.K.1.1.1. the gp27/5 t4-baseplate (t4-bp) family.

    Proteomic databases

    PRIDEi P10930.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1258789.

    Miscellaneous databases

    EvolutionaryTracei P10930.

    Family and domain databases

    Gene3Di 2.160.30.10. 1 hit.
    3.90.1340.10. 1 hit.
    4.10.1070.10. 1 hit.
    InterProi IPR015173. Phage_T4_Gp12.
    IPR023304. Phage_T4_Gp12_dom2.
    IPR011083. Phage_tail_collar_dom.
    IPR027448. Short_tail_fibre_C.
    [Graphical view ]
    Pfami PF07484. Collar. 1 hit.
    PF09089. gp12-short_mid. 1 hit.
    PF14928. S_tail_recep_bd. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide and deduced amino acid sequence of bacteriophage T4 gene 12."
      Selivanov N.A., Prilipov A.G., Mesyanzhinov V.V.
      Nucleic Acids Res. 16:2334-2334(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: D.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "Using transposon Tn5 insertions to sequence bacteriophage T4 gene 11."
      Barrett B.K., Berget P.B.
      DNA 8:287-295(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-57.
      Strain: D.
    4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-4.
      Strain: D.
    5. "Homotrimeric, beta-stranded viral adhesins and tail proteins."
      Weigele P.R., Scanlon E., King J.
      J. Bacteriol. 185:4022-4030(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    6. "Crystal structure of a heat and protease-stable part of the bacteriophage T4 short tail fibre."
      van Raaij M.J., Schoehn G., Burda M.R., Miller S.
      J. Mol. Biol. 314:1137-1146(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 250-527.

    Entry informationi

    Entry nameiFIB12_BPT4
    AccessioniPrimary (citable) accession number: P10930
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1989
    Last sequence update: May 5, 2009
    Last modified: October 1, 2014
    This is version 99 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references

    External Data

    Dasty 3