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P10928

- BP10_BPT4

UniProt

P10928 - BP10_BPT4

Protein

Base plate structural protein gp10

Gene

10

Organism
Enterobacteria phage T4 (Bacteriophage T4)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 77 (03 Sep 2014)
      Sequence version 1 (01 Jul 1989)
      Previous versions | rss
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    Functioni

    Structural component of the baseplate. The key components in the baseplate protein complex are the 6-fold-related gp10 trimers. During infection, the baseplate undergoes a conformational change from a dome-shaped to a star-shaped structure. At this point, gp10 rotates and acts as a lever that unfolds the short tail fibers, which then interact with host cell surface receptors.

    GO - Biological processi

    1. viral life cycle Source: InterPro

    Protein family/group databases

    TCDBi1.K.1.1.1. the gp27/5 t4-baseplate (t4-bp) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Base plate structural protein gp10
    Alternative name(s):
    Base plate wedge protein 10
    Gene product 10
    Short name:
    gp10
    Gene namesi
    Name:10
    OrganismiEnterobacteria phage T4 (Bacteriophage T4)
    Taxonomic identifieri10665 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeTevenvirinaeT4likevirus
    Virus hostiEscherichia coli [TaxID: 562]
    ProteomesiUP000009087: Genome

    Subcellular locationi

    GO - Cellular componenti

    1. virion Source: CACAO

    Keywords - Cellular componenti

    Viral baseplate protein, Viral tail protein, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 602602Base plate structural protein gp10PRO_0000165000Add
    BLAST

    Interactioni

    Subunit structurei

    The baseplate wedge of bacteriophage T4 consists of seven gene products namely, gp11, gp10, gp7, gp8, gp6, gp53, and gp25.

    Structurei

    Secondary structure

    1
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi414 – 4163
    Beta strandi420 – 4234
    Beta strandi425 – 4273
    Beta strandi432 – 4354
    Beta strandi439 – 4413
    Helixi446 – 4538
    Beta strandi459 – 4646
    Helixi470 – 4734
    Beta strandi477 – 4804
    Turni497 – 4993
    Beta strandi500 – 5067
    Beta strandi512 – 5165
    Beta strandi523 – 5253
    Helixi529 – 5313
    Beta strandi596 – 6027

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2FKKX-ray1.20A397-602[»]
    2FL8electron microscopy1.20A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R1-602[»]
    2FL9electron microscopy17.00A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R1-602[»]
    ProteinModelPortaliP10928.
    SMRiP10928. Positions 406-602.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP10928.

    Family & Domainsi

    Family and domain databases

    InterProiIPR008987. Baseplate_struct_prot_Gp9/10.
    [Graphical view]
    PfamiPF07880. T4_gp9_10. 1 hit.
    [Graphical view]
    SUPFAMiSSF50017. SSF50017. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P10928-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKQNINIGNV VDDGTGDYLR KGGIKINENF DELYYELGDG DVPYSAGAWK    50
    TYNASSGQTL TAEWGKSYAI NTSSGRVTIN LPKGTVNDYN KVIRARDVFA 100
    TWNVNPVTLV AASGDTIKGS AVPVEINVRF SDLELVYCAP GRWEYVKNKQ 150
    IDKITSSDIS NVARKEFLVE VQGQTDFLDV FRGTSYNVNN IRVKHRGNEL 200
    YYGDVFSENS DFGSPGENEG ELVPLDGFNI RLRQPCNIGD TVQIETFMDG 250
    VSQWRSSYTR RQIRLLDSKL TSKTSLEGSI YVTDLSTMKS IPFSAFGLIP 300
    GEPINPNSLE VRFNGILQEL AGTVGMPLFH CVGADSDDEV ECSVLGGTWE 350
    QSHTDYSVET DENGIPEILH FDSVFEHGDI INITWFNNDL GTLLTKDEII 400
    DETDNLYVSQ GPGVDISGDV NLTDFDKIGW PNVEAVQSYQ RAFNAVSNIF 450
    DTIYPIGTIY ENAVNPNNPV TYMGFGSWKL FGQGKVLVGW NEDISDPNFA 500
    LNNNDLDSGG NPSHTAGGTG GSTSVTLENA NLPATETDEE VLIVDENGSV 550
    IVGGCQYDPD ESGPIYTKYR EAKASTNSTH TPPTSITNIQ PYITVYRWIR 600
    IA 602
    Length:602
    Mass (Da):66,232
    Last modified:July 1, 1989 - v1
    Checksum:i1159B8C7EBB8EF54
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X14192 Genomic DNA. Translation: CAA32396.1.
    AF158101 Genomic DNA. Translation: AAD42415.1.
    M26253 Genomic DNA. Translation: AAA32493.1.
    PIRiS04083. GEBPT4.
    RefSeqiNP_049768.1. NC_000866.4.

    Genome annotation databases

    GeneIDi1258808.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X14192 Genomic DNA. Translation: CAA32396.1 .
    AF158101 Genomic DNA. Translation: AAD42415.1 .
    M26253 Genomic DNA. Translation: AAA32493.1 .
    PIRi S04083. GEBPT4.
    RefSeqi NP_049768.1. NC_000866.4.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2FKK X-ray 1.20 A 397-602 [» ]
    2FL8 electron microscopy 1.20 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R 1-602 [» ]
    2FL9 electron microscopy 17.00 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R 1-602 [» ]
    ProteinModelPortali P10928.
    SMRi P10928. Positions 406-602.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    TCDBi 1.K.1.1.1. the gp27/5 t4-baseplate (t4-bp) family.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1258808.

    Miscellaneous databases

    EvolutionaryTracei P10928.

    Family and domain databases

    InterProi IPR008987. Baseplate_struct_prot_Gp9/10.
    [Graphical view ]
    Pfami PF07880. T4_gp9_10. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50017. SSF50017. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: D.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "Using transposon Tn5 insertions to sequence bacteriophage T4 gene 11."
      Barrett B.K., Berget P.B.
      DNA 8:287-295(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 535-602.
      Strain: D.
    4. "Evolution of bacteriophage tails: Structure of T4 gene product 10."
      Leiman P.G., Shneider M.M., Mesyanzhinov V.V., Rossmann M.G.
      J. Mol. Biol. 358:912-921(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.2 ANGSTROMS) OF 397-602.

    Entry informationi

    Entry nameiBP10_BPT4
    AccessioniPrimary (citable) accession number: P10928
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1989
    Last sequence update: July 1, 1989
    Last modified: September 3, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    The predicted MW of Gp10 is about 22 kDa smaller than in mature phage particles. Therefore Gp10 may exist as a hybrid protein consisting of two neighboring gene products.

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references

    External Data

    Dasty 3