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P10928

- BP10_BPT4

UniProt

P10928 - BP10_BPT4

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Protein

Base plate structural protein gp10

Gene

10

Organism
Enterobacteria phage T4 (Bacteriophage T4)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Structural component of the baseplate. The key components in the baseplate protein complex are the 6-fold-related gp10 trimers. During infection, the baseplate undergoes a conformational change from a dome-shaped to a star-shaped structure. At this point, gp10 rotates and acts as a lever that unfolds the short tail fibers, which then interact with host cell surface receptors.

GO - Biological processi

  1. viral life cycle Source: InterPro
Complete GO annotation...

Protein family/group databases

TCDBi1.K.1.1.1. the gp27/5 t4-baseplate (t4-bp) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Base plate structural protein gp10
Alternative name(s):
Base plate wedge protein 10
Gene product 10
Short name:
gp10
Gene namesi
Name:10
OrganismiEnterobacteria phage T4 (Bacteriophage T4)
Taxonomic identifieri10665 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaeTevenvirinaeT4likevirus
Virus hostiEscherichia coli [TaxID: 562]
ProteomesiUP000009087: Genome

Subcellular locationi

GO - Cellular componenti

  1. virion Source: CACAO
Complete GO annotation...

Keywords - Cellular componenti

Viral baseplate protein, Viral tail protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 602602Base plate structural protein gp10PRO_0000165000Add
BLAST

Interactioni

Subunit structurei

The baseplate wedge of bacteriophage T4 consists of seven gene products namely, gp11, gp10, gp7, gp8, gp6, gp53, and gp25.

Structurei

Secondary structure

1
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi414 – 4163
Beta strandi420 – 4234
Beta strandi425 – 4273
Beta strandi432 – 4354
Beta strandi439 – 4413
Helixi446 – 4538
Beta strandi459 – 4646
Helixi470 – 4734
Beta strandi477 – 4804
Turni497 – 4993
Beta strandi500 – 5067
Beta strandi512 – 5165
Beta strandi523 – 5253
Helixi529 – 5313
Beta strandi596 – 6027

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FKKX-ray1.20A397-602[»]
2FL8electron microscopy1.20A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R1-602[»]
2FL9electron microscopy17.00A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R1-602[»]
ProteinModelPortaliP10928.
SMRiP10928. Positions 406-602.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP10928.

Family & Domainsi

Family and domain databases

InterProiIPR008987. Baseplate_struct_prot_Gp9/10.
[Graphical view]
PfamiPF07880. T4_gp9_10. 1 hit.
[Graphical view]
SUPFAMiSSF50017. SSF50017. 1 hit.

Sequencei

Sequence statusi: Complete.

P10928-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKQNINIGNV VDDGTGDYLR KGGIKINENF DELYYELGDG DVPYSAGAWK
60 70 80 90 100
TYNASSGQTL TAEWGKSYAI NTSSGRVTIN LPKGTVNDYN KVIRARDVFA
110 120 130 140 150
TWNVNPVTLV AASGDTIKGS AVPVEINVRF SDLELVYCAP GRWEYVKNKQ
160 170 180 190 200
IDKITSSDIS NVARKEFLVE VQGQTDFLDV FRGTSYNVNN IRVKHRGNEL
210 220 230 240 250
YYGDVFSENS DFGSPGENEG ELVPLDGFNI RLRQPCNIGD TVQIETFMDG
260 270 280 290 300
VSQWRSSYTR RQIRLLDSKL TSKTSLEGSI YVTDLSTMKS IPFSAFGLIP
310 320 330 340 350
GEPINPNSLE VRFNGILQEL AGTVGMPLFH CVGADSDDEV ECSVLGGTWE
360 370 380 390 400
QSHTDYSVET DENGIPEILH FDSVFEHGDI INITWFNNDL GTLLTKDEII
410 420 430 440 450
DETDNLYVSQ GPGVDISGDV NLTDFDKIGW PNVEAVQSYQ RAFNAVSNIF
460 470 480 490 500
DTIYPIGTIY ENAVNPNNPV TYMGFGSWKL FGQGKVLVGW NEDISDPNFA
510 520 530 540 550
LNNNDLDSGG NPSHTAGGTG GSTSVTLENA NLPATETDEE VLIVDENGSV
560 570 580 590 600
IVGGCQYDPD ESGPIYTKYR EAKASTNSTH TPPTSITNIQ PYITVYRWIR

IA
Length:602
Mass (Da):66,232
Last modified:July 1, 1989 - v1
Checksum:i1159B8C7EBB8EF54
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14192 Genomic DNA. Translation: CAA32396.1.
AF158101 Genomic DNA. Translation: AAD42415.1.
M26253 Genomic DNA. Translation: AAA32493.1.
PIRiS04083. GEBPT4.
RefSeqiNP_049768.1. NC_000866.4.

Genome annotation databases

GeneIDi1258808.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14192 Genomic DNA. Translation: CAA32396.1 .
AF158101 Genomic DNA. Translation: AAD42415.1 .
M26253 Genomic DNA. Translation: AAA32493.1 .
PIRi S04083. GEBPT4.
RefSeqi NP_049768.1. NC_000866.4.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2FKK X-ray 1.20 A 397-602 [» ]
2FL8 electron microscopy 1.20 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R 1-602 [» ]
2FL9 electron microscopy 17.00 A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R 1-602 [» ]
ProteinModelPortali P10928.
SMRi P10928. Positions 406-602.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

TCDBi 1.K.1.1.1. the gp27/5 t4-baseplate (t4-bp) family.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1258808.

Miscellaneous databases

EvolutionaryTracei P10928.

Family and domain databases

InterProi IPR008987. Baseplate_struct_prot_Gp9/10.
[Graphical view ]
Pfami PF07880. T4_gp9_10. 1 hit.
[Graphical view ]
SUPFAMi SSF50017. SSF50017. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: D.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "Using transposon Tn5 insertions to sequence bacteriophage T4 gene 11."
    Barrett B.K., Berget P.B.
    DNA 8:287-295(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 535-602.
    Strain: D.
  4. "Evolution of bacteriophage tails: Structure of T4 gene product 10."
    Leiman P.G., Shneider M.M., Mesyanzhinov V.V., Rossmann M.G.
    J. Mol. Biol. 358:912-921(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.2 ANGSTROMS) OF 397-602.

Entry informationi

Entry nameiBP10_BPT4
AccessioniPrimary (citable) accession number: P10928
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

The predicted MW of Gp10 is about 22 kDa smaller than in mature phage particles. Therefore Gp10 may exist as a hybrid protein consisting of two neighboring gene products.

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

External Data

Dasty 3