P10887 (MDH_NITAL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: Malate dehydrogenase EC=1.1.1.37
Organism	Nitzschia alba (Marine diatom)
Taxonomic identifier	2858 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Stramenopiles › Bacillariophyta › Bacillariophyceae › Bacillariophycidae › Bacillariales › Bacillariaceae › Nitzschia

Protein attributes

Sequence length	32 AA.
Sequence status	Fragment.
Protein existence	Evidence at protein level

General annotation (Comments)

Catalytic activity	(S)-malate + NAD+ = oxaloacetate + NADH.
Subunit structure	Homooctamer Probable.
Sequence similarities	Belongs to the LDH/MDH superfamily. MDH type 1 family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	NAD
Molecular function	Oxidoreductase
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	tricarboxylic acid cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	L-malate dehydrogenase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›32	›32	Malate dehydrogenase		PRO_0000113341
Experimental info
	Non-terminal residue	32	1

Sequences

	Sequence		Length	Mass (Da)
	P10887 [UniParc]. Last modified July 1, 1989. Version 1. Checksum: 83F0E9E0BAADB4C2	FASTA	32	3,326
	10 20 30 RKVAVMGAAG GIGQPLSLLL KLSPQVTELS KY

References

[1]	"Purification and molecular properties of malate dehydrogenase from the marine diatom Nitzschia alba." Yueh A.Y., Chung C.-S., Lai Y.-K. Biochem. J. 258:221-228(1989) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE.

Cross-references

Sequence databases
PIR	S03352.
3D structure databases
ProteinModelPortal	P10887.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	3.40.50.720. 1 hit.
InterPro	IPR001236. Lactate/malate_DH_N. IPR016040. NAD(P)-bd_dom. [Graphical view]
Pfam	PF00056. Ldh_1_N. 1 hit. [Graphical view]
PROSITE	PS00068. MDH. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MDH_NITAL

Accession

Primary (citable) accession number: P10887

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
Last sequence update:	July 1, 1989
Last modified:	May 29, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)