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P10887

- MDH_NITAL

UniProt

P10887 - MDH_NITAL

Protein

Malate dehydrogenase

Gene
N/A
Organism
Nitzschia alba (Marine diatom)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Catalytic activityi

    (S)-malate + NAD+ = oxaloacetate + NADH.PROSITE-ProRule annotation

    GO - Molecular functioni

    1. L-malate dehydrogenase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellular carbohydrate metabolic process Source: InterPro
    2. tricarboxylic acid cycle Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Tricarboxylic acid cycle

    Keywords - Ligandi

    NAD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Malate dehydrogenase (EC:1.1.1.37)
    OrganismiNitzschia alba (Marine diatom)
    Taxonomic identifieri2858 [NCBI]
    Taxonomic lineageiEukaryotaStramenopilesBacillariophytaBacillariophyceaeBacillariophycidaeBacillarialesBacillariaceaeNitzschia

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – ›32›32Malate dehydrogenasePRO_0000113341Add
    BLAST

    Interactioni

    Subunit structurei

    Homooctamer.Curated

    Structurei

    3D structure databases

    ProteinModelPortaliP10887.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the LDH/MDH superfamily. MDH type 1 family.Curated

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR001557. L-lactate/malate_DH.
    IPR001236. Lactate/malate_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR11540. PTHR11540. 1 hit.
    PfamiPF00056. Ldh_1_N. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    P10887-1 [UniParc]FASTAAdd to Basket

    « Hide

    RKVAVMGAAG GIGQPLSLLL KLSPQVTELS KY                      32
    Length:32
    Mass (Da):3,326
    Last modified:July 1, 1989 - v1
    Checksum:i83F0E9E0BAADB4C2
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei32 – 321

    Sequence databases

    PIRiS03352.

    Cross-referencesi

    Sequence databases

    PIRi S03352.

    3D structure databases

    ProteinModelPortali P10887.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR001557. L-lactate/malate_DH.
    IPR001236. Lactate/malate_DH_N.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR11540. PTHR11540. 1 hit.
    Pfami PF00056. Ldh_1_N. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Purification and molecular properties of malate dehydrogenase from the marine diatom Nitzschia alba."
      Yueh A.Y., Chung C.-S., Lai Y.-K.
      Biochem. J. 258:221-228(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: PROTEIN SEQUENCE.

    Entry informationi

    Entry nameiMDH_NITAL
    AccessioniPrimary (citable) accession number: P10887
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1989
    Last sequence update: July 1, 1989
    Last modified: October 1, 2014
    This is version 70 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3