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P10835

- MTC3_PBCVC

UniProt

P10835 - MTC3_PBCVC

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Protein

Modification methylase CviBIII

Gene
CVIBIIIM
Organism
Paramecium bursaria Chlorella virus NC1A (PBCV-NC1A)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands.

Catalytic activityi

S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

GO - Molecular functioni

  1. nucleic acid binding Source: InterPro
  2. site-specific DNA-methyltransferase (adenine-specific) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Ligandi

S-adenosyl-L-methionine

Protein family/group databases

REBASEi752. M.CviBIII.

Names & Taxonomyi

Protein namesi
Recommended name:
Modification methylase CviBIII (EC:2.1.1.72)
Short name:
M.CviBIII
Alternative name(s):
Adenine-specific methyltransferase CviBIII
Gene namesi
Name:CVIBIIIM
OrganismiParamecium bursaria Chlorella virus NC1A (PBCV-NC1A)
Taxonomic identifieri46020 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stagePhycodnaviridaeChlorovirus
Virus hostiChlorella [TaxID: 3071]

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 377377Modification methylase CviBIIIPRO_0000087948Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP10835.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR002052. DNA_methylase_N6_adenine_CS.
IPR002296. N12N6_MeTrfase.
IPR029063. SAM-dependent_MTases-like.
[Graphical view]
PRINTSiPR00507. N12N6MTFRASE.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS00092. N6_MTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P10835-1 [UniParc]FASTAAdd to Basket

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MNVEQYTQVT TDFEKTLTKE KKSKQGIFFT PKTVREKLFG FTEHFQNTPG    50
FSILEPSCGT GEIISECVER FPLASIKGVE LDNDMSTICS KKYAEYNVDI 100
VNEDFLLWKG GKFDFIVGNP PYVVRPSGYK NDNRIAKGRS NLYVEFLYKC 150
ITEHLKEDGI LAFIIPSTIG NSSFYEPIRK LIITLDILSF EILDKHDFCD 200
TNTRLCSIVI KNSPGTGKYT YRDYICDKDI PHHGNSYIGS LDLKFKTGFA 250
WANVNKFFTD KSEIPFFTSS NIKLNEIHIG DKMKYLTQDT TKFFTGKALL 300
IKTASAGKRG GRFEFGFSLY ENDKWAVDND IIVIQGPDTV LSIVQDVLMK 350
DVTNEFINIL VNNGHISMKL LKSIPLF 377
Length:377
Mass (Da):42,895
Last modified:July 1, 1989 - v1
Checksum:iB22D471367D61BBC
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X06618 Genomic DNA. Translation: CAA29835.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X06618 Genomic DNA. Translation: CAA29835.1 .

3D structure databases

ProteinModelPortali P10835.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

REBASEi 752. M.CviBIII.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
InterProi IPR002052. DNA_methylase_N6_adenine_CS.
IPR002296. N12N6_MeTrfase.
IPR029063. SAM-dependent_MTases-like.
[Graphical view ]
PRINTSi PR00507. N12N6MTFRASE.
SUPFAMi SSF53335. SSF53335. 1 hit.
PROSITEi PS00092. N6_MTASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning and characterization of the gene encoding the DNA methyltransferase, M.CviBIII, from Chlorella virus NC-1A."
    Narva K.E., Wendell D.L., Skrdla M.P., van Etten J.L.
    Nucleic Acids Res. 15:9807-9823(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiMTC3_PBCVC
AccessioniPrimary (citable) accession number: P10835
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: June 11, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Documents

  1. Restriction enzymes and methylases
    Classification of restriction enzymes and methylases and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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