Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Porin thermoregulatory protein EnvY

Gene

envY

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Influences the temperature-dependent expression of several E.coli envelope proteins, most notably the porins OmpF and OmpC and the lambda receptor, LamB.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi165 – 184H-T-H motifPROSITE-ProRule annotationAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciEcoCyc:PD00969.
ECOL316407:JW0555-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Porin thermoregulatory protein EnvY
Gene namesi
Name:envY
Ordered Locus Names:b0566, JW0555
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10268. envY.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: GO_Central
  • membrane Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001945081 – 253Porin thermoregulatory protein EnvYAdd BLAST253

Proteomic databases

PaxDbiP10805.
PRIDEiP10805.

Interactioni

Protein-protein interaction databases

BioGridi4262188. 4 interactors.
IntActiP10805. 14 interactors.
STRINGi511145.b0566.

Structurei

3D structure databases

ProteinModelPortaliP10805.
SMRiP10805.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG2207. LUCA.
HOGENOMiHOG000127052.
InParanoidiP10805.
KOiK11920.
OMAiPHINRNI.
PhylomeDBiP10805.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P10805-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLSSSEPCV VILTEKEVEV SVNNHATFTL PKNYLAAFAC NNNVIELSTL
60 70 80 90 100
NHVLITHINR NIINDYLLFL NKNLTCVKPW SRLATPVIAC HSRTPEVFRL
110 120 130 140 150
AANHSKQQPS RPCEAELTRA LLFTVLSNFL EQSRFIALLM YILRSSVRDS
160 170 180 190 200
VCRIIQSDIQ HYWNLRIVAS SLCLSPSLLK KKLKNENTSY SQIVTECRMR
210 220 230 240 250
YAVQMLLMDN KNITQVAQLC GYSSTSYFIS VFKAFYGLTP LNYLAKQRQK

VMW
Length:253
Mass (Da):29,019
Last modified:November 1, 1997 - v2
Checksum:i8FB1554CC5C4238E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti61N → NR in CAA31900 (PubMed:2536924).Curated1
Sequence conflicti93Missing in CAA31900 (PubMed:2536924).Curated1
Sequence conflicti99R → P in CAA31900 (PubMed:2536924).Curated1
Sequence conflicti150S → T in CAA31900 (PubMed:2536924).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13548 Genomic DNA. Translation: CAA31900.1.
U82598 Genomic DNA. Translation: AAB40763.1.
U00096 Genomic DNA. Translation: AAC73667.1.
AP009048 Genomic DNA. Translation: BAA35200.1.
PIRiD64789.
RefSeqiNP_415098.1. NC_000913.3.
WP_001177471.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73667; AAC73667; b0566.
BAA35200; BAA35200; BAA35200.
GeneIDi949114.
KEGGiecj:JW0555.
eco:b0566.
PATRICi32116300. VBIEscCol129921_0590.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X13548 Genomic DNA. Translation: CAA31900.1.
U82598 Genomic DNA. Translation: AAB40763.1.
U00096 Genomic DNA. Translation: AAC73667.1.
AP009048 Genomic DNA. Translation: BAA35200.1.
PIRiD64789.
RefSeqiNP_415098.1. NC_000913.3.
WP_001177471.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP10805.
SMRiP10805.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262188. 4 interactors.
IntActiP10805. 14 interactors.
STRINGi511145.b0566.

Proteomic databases

PaxDbiP10805.
PRIDEiP10805.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73667; AAC73667; b0566.
BAA35200; BAA35200; BAA35200.
GeneIDi949114.
KEGGiecj:JW0555.
eco:b0566.
PATRICi32116300. VBIEscCol129921_0590.

Organism-specific databases

EchoBASEiEB0264.
EcoGeneiEG10268. envY.

Phylogenomic databases

eggNOGiCOG2207. LUCA.
HOGENOMiHOG000127052.
InParanoidiP10805.
KOiK11920.
OMAiPHINRNI.
PhylomeDBiP10805.

Enzyme and pathway databases

BioCyciEcoCyc:PD00969.
ECOL316407:JW0555-MONOMER.

Miscellaneous databases

PROiP10805.

Family and domain databases

Gene3Di1.10.10.60. 1 hit.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
IPR020449. Tscrpt_reg_HTH_AraC-type.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
PRINTSiPR00032. HTHARAC.
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiENVY_ECOLI
AccessioniPrimary (citable) accession number: P10805
Secondary accession number(s): P77778
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: November 1, 1997
Last modified: November 2, 2016
This is version 128 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.