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P10801

- ODP1_AZOVI

UniProt

P10801 - ODP1_AZOVI

Protein

Pyruvate dehydrogenase E1 component

Gene
N/A
Organism
Azotobacter vinelandii
Status
Reviewed - Annotation score: 2 out of 5- Protein predictedi
  1. Functioni

    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

    Catalytic activityi

    Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

    Cofactori

    Thiamine pyrophosphate.

    GO - Molecular functioni

    1. pyruvate dehydrogenase (acetyl-transferring) activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Pyruvate, Thiamine pyrophosphate

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyruvate dehydrogenase E1 component (EC:1.2.4.1)
    OrganismiAzotobacter vinelandii
    Taxonomic identifieri354 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaeAzotobacter

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 45›45Pyruvate dehydrogenase E1 componentPRO_0000162239Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.

    Structurei

    3D structure databases

    ProteinModelPortaliP10801.
    SMRiP10801. Positions 1-42.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.40.50.920. 1 hit.
    InterProiIPR009014. Transketo_C/Pyr-ferredox_oxred.
    [Graphical view]
    SUPFAMiSSF52922. SSF52922. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    P10801-1 [UniParc]FASTAAdd to Basket

    « Hide

    EVDRYWVVLA ALEALADRGD IEAKVVAEAI AKFGIDPDKR NPLDC        45
    Length:45
    Mass (Da):4,957
    Last modified:July 1, 1989 - v1
    Checksum:iC2929BB637D1B032
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X12455 Genomic DNA. Translation: CAA30986.1.
    PIRiS12208.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X12455 Genomic DNA. Translation: CAA30986.1 .
    PIRi S12208.

    3D structure databases

    ProteinModelPortali P10801.
    SMRi P10801. Positions 1-42.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.50.920. 1 hit.
    InterProi IPR009014. Transketo_C/Pyr-ferredox_oxred.
    [Graphical view ]
    SUPFAMi SSF52922. SSF52922. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The dihydrolipoyltransacetylase component of the pyruvate dehydrogenase complex from Azotobacter vinelandii. Molecular cloning and sequence analysis."
      Hanemaaijer R., Janssen A., de Kok A., Veeger C.
      Eur. J. Biochem. 174:593-599(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 478 / NRS 16 / DSM 2289 / VKM B-1617.

    Entry informationi

    Entry nameiODP1_AZOVI
    AccessioniPrimary (citable) accession number: P10801
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1989
    Last sequence update: July 1, 1989
    Last modified: June 11, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program