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P10773 (LYB_BACIU) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
B-enzyme
Alternative name(s):
Lysozyme
EC=3.2.1.17
Gene names
Name:lyzB
OrganismBacillus subtilis
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length117 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Miscellaneous

Usually lysozymes have a catalytic site with Asp and Glu, but B-enzyme has no Glu (two Asp for catalytic site).

Ontologies

Keywords
   Molecular functionAntimicrobial
Bacteriolytic enzyme
Glycosidase
Hydrolase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processcytolysis

Inferred from electronic annotation. Source: UniProtKB-KW

defense response to bacterium

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionlysozyme activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 117117B-enzyme
PRO_0000057725

Sites

Active site891 Potential

Sequences

Sequence LengthMass (Da)Tools
P10773 [UniParc].

Last modified July 1, 1989. Version 1.
Checksum: 322C5FD7C5EB3762

FASTA11712,732
        10         20         30         40         50         60 
ISPLGSVTKK NQDSTAYNWT GNKTANGNWP VLGICAVHRK KDIGGSGNSP VIPFGTTLKT 

        70         80         90        100        110 
DKDIWLPDGV GYKSSFNVDD TGSGPKKTDY WIDIYYSKDT KAAINYGVVK LSYTYST 

« Hide

References

[1]"Amino acid sequence of a lysozyme (B-enzyme) from Bacillus subtilis YT-25."
Kamei K., Hara S., Ikenaka T., Murao S.
J. Biochem. 104:832-836(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE.
Strain: YT-25.

Cross-references

Sequence databases

PIRJX0053.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameLYB_BACIU
AccessionPrimary (citable) accession number: P10773
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: October 16, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries