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Protein

Serine/threonine-protein kinase mos

Gene

MOS

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei91 – 911ATPPROSITE-ProRule annotation
Active sitei205 – 2051Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi70 – 789ATPPROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.10.2. 1306.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase mos (EC:2.7.11.1)
Alternative name(s):
Oocyte maturation factor mos
Gene namesi
Name:MOS
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 2

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 349349Serine/threonine-protein kinase mosPRO_0000086351Add
BLAST

Proteomic databases

PaxDbiP10741.

Expressioni

Gene expression databases

BgeeiENSGALG00000015406.
ExpressionAtlasiP10741. baseline.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000024805.

Structurei

3D structure databases

ProteinModelPortaliP10741.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini64 – 345282Protein kinasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0192. Eukaryota.
COG0515. LUCA.
GeneTreeiENSGT00760000118807.
HOGENOMiHOG000290647.
HOVERGENiHBG052499.
InParanoidiP10741.
KOiK04367.
OMAiIKQVNRC.
OrthoDBiEOG091G0PY9.
PhylomeDBiP10741.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P10741-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSPIPFNSF LPLELSPSAD LRPCSSPVVI PGKDGKAFLG GTPSPRTRRL
60 70 80 90 100
PPRLAWCSID WDRLCLLQPL GSGGFGAVYK ATYHGVTVAV KQVKKSSKNR
110 120 130 140 150
LASRQSFWAE LNVARLQHDN VVRVVAASTC APASQNSLGT IIMEYVGNVT
160 170 180 190 200
LHHVIYGTRD AWRQGEEEEG GCGRKALSMA EAVCYSCDIV TGLAFLHSQG
210 220 230 240 250
IVHLDLKPAN ILITEHGACK IGDFGCSQRL EEGLSQSHHV CQQGGTYTHR
260 270 280 290 300
APELLKGERV TAKADIYSFA ITLWQIVMRE QPYLGERQYV LYAVVAYNLR
310 320 330 340
PPLAAAIFHE SAVGQRLRSI ISCCWKADVE ERLSAAQLLP SLRALKENL
Length:349
Mass (Da):38,263
Last modified:July 1, 1989 - v1
Checksum:i19182B0AC8934BF6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M19412 Genomic DNA. Translation: AAA48959.1.
PIRiA28130. TVCHMS.
RefSeqiNP_001026687.1. NM_001031516.1.
UniGeneiGga.32094.

Genome annotation databases

EnsembliENSGALT00000024851; ENSGALP00000024805; ENSGALG00000015406.
GeneIDi428537.
KEGGigga:428537.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M19412 Genomic DNA. Translation: AAA48959.1.
PIRiA28130. TVCHMS.
RefSeqiNP_001026687.1. NM_001031516.1.
UniGeneiGga.32094.

3D structure databases

ProteinModelPortaliP10741.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000024805.

Proteomic databases

PaxDbiP10741.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000024851; ENSGALP00000024805; ENSGALG00000015406.
GeneIDi428537.
KEGGigga:428537.

Organism-specific databases

CTDi4342.

Phylogenomic databases

eggNOGiKOG0192. Eukaryota.
COG0515. LUCA.
GeneTreeiENSGT00760000118807.
HOGENOMiHOG000290647.
HOVERGENiHBG052499.
InParanoidiP10741.
KOiK04367.
OMAiIKQVNRC.
OrthoDBiEOG091G0PY9.
PhylomeDBiP10741.

Enzyme and pathway databases

BRENDAi2.7.10.2. 1306.

Miscellaneous databases

PROiP10741.

Gene expression databases

BgeeiENSGALG00000015406.
ExpressionAtlasiP10741. baseline.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiMOS_CHICK
AccessioniPrimary (citable) accession number: P10741
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: September 7, 2016
This is version 111 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.