Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Anti-sigma F factor antagonist

Gene

spoIIAA

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition.1 Publication

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Sporulation

Enzyme and pathway databases

BioCyciBSUB:BSU23470-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Anti-sigma F factor antagonist
Alternative name(s):
Stage II sporulation protein AA
Gene namesi
Name:spoIIAA
Ordered Locus Names:BSU23470
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved2 Publications
Chaini2 – 117116Anti-sigma F factor antagonistPRO_0000194204Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei58 – 581Phosphoserine1 Publication

Post-translational modificationi

Phosphorylated by SpoIIAB on a serine residue.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP10727.

PTM databases

iPTMnetiP10727.

Interactioni

Protein-protein interaction databases

IntActiP10727. 1 interaction.
STRINGi224308.Bsubs1_010100012881.

Structurei

Secondary structure

1
117
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi7 – 104Combined sources
Beta strandi13 – 164Combined sources
Helixi26 – 3813Combined sources
Beta strandi45 – 495Combined sources
Helixi60 – 7415Combined sources
Turni85 – 884Combined sources
Helixi89 – 946Combined sources
Helixi97 – 993Combined sources
Helixi106 – 1083Combined sources
Helixi110 – 1123Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1AUZNMR-A2-117[»]
1BUZNMR-A2-117[»]
ProteinModelPortaliP10727.
SMRiP10727. Positions 2-117.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP10727.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 113111STASPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 STAS domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG41082AN. Bacteria.
COG1366. LUCA.
HOGENOMiHOG000270156.
InParanoidiP10727.
KOiK06378.
OMAiKVFEIFN.
PhylomeDBiP10727.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
InterProiIPR003658. Anti-sigma_ant.
IPR014237. Anti-sigma_F_ant.
IPR002645. STAS_dom.
[Graphical view]
PfamiPF01740. STAS. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 1 hit.
TIGRFAMsiTIGR00377. ant_ant_sig. 1 hit.
TIGR02886. spore_II_AA. 1 hit.
PROSITEiPS50801. STAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P10727-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLGIDMNVK ESVLCIRLTG ELDHHTAETL KQKVTQSLEK DDIRHIVLNL
60 70 80 90 100
EDLSFMDSSG LGVILGRYKQ IKQIGGEMVV CAISPAVKRL FDMSGLFKII
110
RFEQSEQQAL LTLGVAS
Length:117
Mass (Da):12,990
Last modified:January 23, 2007 - v3
Checksum:i2333E74207568AC2
GO

Sequence cautioni

The sequence AAA22789 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M17643 Genomic DNA. Translation: AAA22789.1. Different initiation.
D84432 Genomic DNA. Translation: BAA12653.1.
AL009126 Genomic DNA. Translation: CAB14279.1.
PIRiA55646.
RefSeqiNP_390228.1. NC_000964.3.
WP_004398633.1. NZ_JNCM01000036.1.

Genome annotation databases

EnsemblBacteriaiCAB14279; CAB14279; BSU23470.
GeneIDi938730.
KEGGibsu:BSU23470.
PATRICi18976513. VBIBacSub10457_2447.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M17643 Genomic DNA. Translation: AAA22789.1. Different initiation.
D84432 Genomic DNA. Translation: BAA12653.1.
AL009126 Genomic DNA. Translation: CAB14279.1.
PIRiA55646.
RefSeqiNP_390228.1. NC_000964.3.
WP_004398633.1. NZ_JNCM01000036.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1AUZNMR-A2-117[»]
1BUZNMR-A2-117[»]
ProteinModelPortaliP10727.
SMRiP10727. Positions 2-117.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP10727. 1 interaction.
STRINGi224308.Bsubs1_010100012881.

PTM databases

iPTMnetiP10727.

Proteomic databases

PaxDbiP10727.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB14279; CAB14279; BSU23470.
GeneIDi938730.
KEGGibsu:BSU23470.
PATRICi18976513. VBIBacSub10457_2447.

Phylogenomic databases

eggNOGiENOG41082AN. Bacteria.
COG1366. LUCA.
HOGENOMiHOG000270156.
InParanoidiP10727.
KOiK06378.
OMAiKVFEIFN.
PhylomeDBiP10727.

Enzyme and pathway databases

BioCyciBSUB:BSU23470-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP10727.

Family and domain databases

Gene3Di3.30.750.24. 1 hit.
InterProiIPR003658. Anti-sigma_ant.
IPR014237. Anti-sigma_F_ant.
IPR002645. STAS_dom.
[Graphical view]
PfamiPF01740. STAS. 1 hit.
[Graphical view]
SUPFAMiSSF52091. SSF52091. 1 hit.
TIGRFAMsiTIGR00377. ant_ant_sig. 1 hit.
TIGR02886. spore_II_AA. 1 hit.
PROSITEiPS50801. STAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSP2AA_BACSU
AccessioniPrimary (citable) accession number: P10727
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1991
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 136 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.