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Protein

37S ribosomal protein MRP2, mitochondrial

Gene

MRP2

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD
  • translation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-34295-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
37S ribosomal protein MRP2, mitochondrial
Gene namesi
Name:MRP2
Ordered Locus Names:YPR166C
ORF Names:P9325.7
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XVI

Organism-specific databases

EuPathDBiFungiDB:YPR166C.
SGDiS000006370. MRP2.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial small ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 1515MitochondrionSequence analysisAdd
BLAST
Chaini16 – 11510037S ribosomal protein MRP2, mitochondrialPRO_0000131017Add
BLAST

Proteomic databases

MaxQBiP10663.

Interactioni

Subunit structurei

Component of the mitochondrial small ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).3 Publications

Protein-protein interaction databases

BioGridi36339. 10 interactions.
IntActiP10663. 2 interactions.
MINTiMINT-2782100.

Structurei

3D structure databases

ProteinModelPortaliP10663.
SMRiP10663. Positions 16-115.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S14P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

HOGENOMiHOG000039864.
InParanoidiP10663.
KOiK02954.
OMAiHCYTRPT.
OrthoDBiEOG706142.

Family and domain databases

InterProiIPR001209. Ribosomal_S14.
IPR018271. Ribosomal_S14_CS.
[Graphical view]
PANTHERiPTHR19836. PTHR19836. 1 hit.
PfamiPF00253. Ribosomal_S14. 1 hit.
[Graphical view]
PROSITEiPS00527. RIBOSOMAL_S14. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P10663-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNFRFPIKT KLPPGFINAR ILRDNFKRQQ FKENEILVKS LKFIARNMNL
60 70 80 90 100
PTKLRLEAQL KLNALPNYMR STQIKNRCVD SGHARFVLSD FRLCRYQFRE
110
NALKGNLPGV KKGIW
Length:115
Mass (Da):13,538
Last modified:July 1, 1989 - v1
Checksum:i90DCF9ABAA72AF8B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M15161 Genomic DNA. Translation: AAA74728.1.
U25840 Genomic DNA. Translation: AAB68153.1.
AY558052 Genomic DNA. Translation: AAS56378.1.
BK006949 Genomic DNA. Translation: DAA11583.1.
PIRiB29138. R3BY14.
RefSeqiNP_015492.1. NM_001184263.1.

Genome annotation databases

EnsemblFungiiYPR166C; YPR166C; YPR166C.
GeneIDi856295.
KEGGisce:YPR166C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M15161 Genomic DNA. Translation: AAA74728.1.
U25840 Genomic DNA. Translation: AAB68153.1.
AY558052 Genomic DNA. Translation: AAS56378.1.
BK006949 Genomic DNA. Translation: DAA11583.1.
PIRiB29138. R3BY14.
RefSeqiNP_015492.1. NM_001184263.1.

3D structure databases

ProteinModelPortaliP10663.
SMRiP10663. Positions 16-115.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi36339. 10 interactions.
IntActiP10663. 2 interactions.
MINTiMINT-2782100.

Proteomic databases

MaxQBiP10663.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYPR166C; YPR166C; YPR166C.
GeneIDi856295.
KEGGisce:YPR166C.

Organism-specific databases

EuPathDBiFungiDB:YPR166C.
SGDiS000006370. MRP2.

Phylogenomic databases

HOGENOMiHOG000039864.
InParanoidiP10663.
KOiK02954.
OMAiHCYTRPT.
OrthoDBiEOG706142.

Enzyme and pathway databases

BioCyciYEAST:G3O-34295-MONOMER.

Miscellaneous databases

PROiP10663.

Family and domain databases

InterProiIPR001209. Ribosomal_S14.
IPR018271. Ribosomal_S14_CS.
[Graphical view]
PANTHERiPTHR19836. PTHR19836. 1 hit.
PfamiPF00253. Ribosomal_S14. 1 hit.
[Graphical view]
PROSITEiPS00527. RIBOSOMAL_S14. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Assembly of the mitochondrial membrane system. MRP1 and MRP2, two yeast nuclear genes coding for mitochondrial ribosomal proteins."
    Myers A.M., Crivellone M.D., Tzagoloff A.
    J. Biol. Chem. 262:3388-3397(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI."
    Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W., Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D., Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E., Churcher C.M.
    , Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H., DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N., Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K., Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M., Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A., Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S., Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D., Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S., Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B., Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A., Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R., Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A., Vo D.H., Hani J.
    Nature 387:103-105(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  5. "Incorporation of the yeast mitochondrial ribosomal protein Mrp2 into ribosomal subunits requires the mitochondrially encoded Var1 protein."
    Davis S.C., Ellis S.R.
    Mol. Gen. Genet. 247:379-386(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBUNIT.
  6. "Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues."
    Saveanu C., Fromont-Racine M., Harington A., Ricard F., Namane A., Jacquier A.
    J. Biol. Chem. 276:15861-15867(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  7. "Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components."
    Gan X., Kitakawa M., Yoshino K., Oshiro N., Yonezawa K., Isono K.
    Eur. J. Biochem. 269:5203-5214(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE MITOCHONDRIAL RIBOSOMAL SMALL COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  8. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    Strain: ATCC 76625 / YPH499.

Entry informationi

Entry nameiRT02_YEAST
AccessioniPrimary (citable) accession number: P10663
Secondary accession number(s): D6W4G7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: July 6, 2016
This is version 133 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XVI
    Yeast (Saccharomyces cerevisiae) chromosome XVI: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.