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Reviewed, UniProtKB/Swiss-Prot P10654 (XYLA_AMPSP)

Last modified September 22, 2009. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Xylose isomerase
    EC=5.3.1.5
Gene names
Name: xylA
OrganismAmpullariella sp. (strain 3876)
Taxonomic identifier1872 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micromonosporineae › Micromonosporaceae › Actinoplanes

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Protein attributes

Sequence length394 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-xylose = D-xylulose. HAMAP MF_00455

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Subunit structure

Homotetramer. HAMAP MF_00455

Subcellular location

Cytoplasm. HAMAP MF_00455

Sequence similarities

Belongs to the xylose isomerase family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
Pentose shunt
Xylose metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionIsomerase
Gene Ontology (GO)
   Biological processD-xylose metabolic process

Inferred from electronic annotation. Source: HAMAP

pentose-phosphate shunt

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmagnesium ion binding

Inferred from electronic annotation. Source: HAMAP

xylose isomerase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 394394Xylose isomerase HAMAP MF_00455
PRO_0000195759

Sites

Active site541 By similarity
Active site571 By similarity
Metal binding1811Magnesium 1 By similarity
Metal binding2171Magnesium 1 By similarity
Metal binding2171Magnesium 2 By similarity
Metal binding2201Magnesium 2 By similarity
Metal binding2451Magnesium 1 By similarity
Metal binding2551Magnesium 2 By similarity
Metal binding2571Magnesium 2 By similarity
Metal binding2921Magnesium 1 By similarity

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Sequences

Sequence LengthMass (Da)Tools
P10654-1 [UniParc].

Last modified July 1, 1989. Version 1.
Checksum: 22070462486F8567

FASTA39443,396
        10         20         30         40         50         60 
MSLQATPDDK FSFGLWTVGW QARDAFGDAT RPVLDPIEAV HKLAEIGAYG VTFHDDDLVP 

        70         80         90        100        110        120 
FGADAATRDG IVAGFSKALD ETGLIVPMVT TNLFTHPVFK DGGFTSNDRS VRRYAIRKVL 

       130        140        150        160        170        180 
RQMDLGAELG AKTLVLWGGR EGAEYDSAKD VGAALDRYRE ALNLLAQYSE DQGYGLPFAI 

       190        200        210        220        230        240 
EPKPNEPRGD ILLPTAGHAI AFVQELERPE LFGINRETGH EQMSNLNFTQ GIAQALWHKK 

       250        260        270        280        290        300 
LFHIDLNGQH GPKFDQDLVF GHGDLLNAFS LVDLLENGPD GGPAYDGPRH FDYKPSRTED 

       310        320        330        340        350        360 
FDGVWESAKD NIRMYLLLKE RAKAFRADPE VQAALAESKV DELRTPTLNP GETYADLLAD 

       370        380        390 
RSAFEDYDAD AVGAKGYGFV KLNQLAIDHL LGAR

« Hide

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References

[1]"Sequence of the Ampullariella sp. strain 3876 gene coding for xylose isomerase."
Saari G.C., Kumar A.A., Kawasaki G.H., Insley M.Y., O'Hara P.J.
J. Bacteriol. 169:612-618(1987) [PubMed: 3027039] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

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Cross-references

Sequence databases

M15050 Genomic DNA. Translation: AAA92578.1.
PIRISMAXA. A27756.

3D structure databases

HSSPHSSP built from PDB template 4XIM based on UniProtKB P12851.
SMRP10654. Positions 3-394.
ModBaseSearch...

Family and domain databases

HAMAPMF_00455.
[Tree]
InterProIPR013022. Xyl_isomerase-like_TIM-brl.
IPR012307. Xyl_isomerase_TIM-brl.
IPR013453. XylA_actinobac.
IPR001998. Xylose_isomerase.
IPR018115. Xylose_isomerase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
PfamPF01261. AP_endonuc_2. 1 hit.
[Graphical view]
PRINTSPR00688. XYLOSISMRASE.
TIGRFAMsTIGR02631. xylA_Arthro. 1 hit.
PROSITEPS51415. XYLOSE_ISOMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameXYLA_AMPSP
AccessionPrimary (citable) accession number: P10654
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: September 22, 2009
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents