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1 to 25 of 36  Show
  1. 1
    "Characterization of multiple human cytochrome P-450 1 cDNAs. The chromosomal localization of the gene and evidence for alternate RNA splicing."
    Okino S.T., Quattrochi L.C., Pendurthi U.R., McBride O.W., Tukey R.H.
    J. Biol. Chem. 262:16072-16079(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT MET-264.
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    "cDNA and amino acid sequences of two members of the human P450IIC gene subfamily."
    Kimura S., Pastewka J., Gelboin H.V., Gonzalez F.J.
    Nucleic Acids Res. 15:10053-10054(1987) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  3. 3
    "Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily."
    Romkes M., Faletto M.B., Blaisdell J.A., Raucy J.L., Goldstein J.A.
    Biochemistry 30:3247-3255(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), VARIANT MET-264.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 4 other entries.

  4. 4
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANTS LYS-139 AND ARG-399.
    Category: Sequences.
    Tissue: Liver and Mammary gland.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12924 other entries.

  5. 5
    NIEHS SNPs program
    Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS LYS-139; VAL-244; MET-264; PHE-269 AND ARG-399.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  6. 6
    "The DNA sequence and comparative analysis of human chromosome 10."
    Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L., Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K., Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L., Taylor A., Battles J.
    , Bird C.P., Ainscough R., Almeida J.P., Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P., Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N., Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A., Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C., Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D., Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C., Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K., Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A., Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S., McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S., Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A., Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A., Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P., Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y., Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D., Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.
    Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1990 other entries.

  7. 7
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  8. 8
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50492 other entries.

  9. 9
    "Isolation of the human cytochrome P-450 IIC8 gene: multiple glucocorticoid responsive elements in the 5' region."
    Ged C., Beaune P.
    Biochim. Biophys. Acta 1088:433-435(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-56.
    Category: Sequences.
    Tissue: Blood.
    Source: UniProtKB/Swiss-Prot (reviewed).
  10. 10
    "Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform."
    Zeldin D.C., DuBois R.N., Falck J.R., Capdevila J.H.
    Arch. Biochem. Biophys. 322:76-86(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-15, NUCLEOTIDE SEQUENCE [MRNA] OF 6-490, FUNCTION, CATALYTIC ACTIVITY, VARIANT LEU-411.
    Category: Function, Sequences.
    Tissue: Kidney.
    Source: UniProtKB/Swiss-Prot (reviewed).
  11. 11
    "Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase."
    Ged C., Umbenhauer D.R., Bellew T.M., Bork R.W., Srivastava P.K., Shinriki N., Lloyd R.S., Guengerich F.P.
    Biochemistry 27:6929-6940(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 11-490 (ISOFORM 1), VARIANTS ASP-154; LYS-193; ARG-249 AND LEU-411.
    Category: Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1 other entry.

  12. 12
    "Cloning, expression and chromosomal localization of a member of the human cytochrome P450IIC gene sub-family."
    Shephard E.A., Phillips I.R., Santisteban I., Palmer C.N., Povey S.
    Ann. Hum. Genet. 53:23-31(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 34-382 (ISOFORM 1), VARIANT LYS-139.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  13. 13
    "Sequence of a human liver cytochrome P-450 cDNA clone."
    Kolyada A.Y.
    Nucleic Acids Res. 18:5550-5550(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 281-490 (ISOFORM 1), VARIANT ARG-399.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  14. 14
    "A frameshift variant of CYP2C8 was identified in a patient who suffered from rhabdomyolysis after administration of cerivastatin."
    Ishikawa C., Ozaki H., Nakajima T., Ishii T., Kanai S., Anjo S., Shirai K., Inoue I.
    J. Hum. Genet. 49:582-585(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: POLYMORPHISM.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  15. 15
    "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."
    Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D., Wang L., Ye M., Zou H.
    J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-100, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Category: PTM / Processing, Sequences.
    Tissue: Liver.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 11205 other entries.

  16. 16
    "Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site."
    Schoch G.A., Yano J.K., Wester M.R., Griffin K.J., Stout C.D., Johnson E.F.
    J. Biol. Chem. 279:9497-9503(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.7 ANGSTROMS) OF 28-490.
    Category: Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).
  17. 17
    "Determinants of cytochrome P450 2C8 substrate binding: structures of complexes with montelukast, troglitazone, felodipine, and 9-cis-retinoic acid."
    Schoch G.A., Yano J.K., Sansen S., Dansette P.M., Stout C.D., Johnson E.F.
    J. Biol. Chem. 283:17227-17237(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.28 ANGSTROMS) OF 28-490 IN COMPLEX WITH INHIBITORS, SUBSTRATE-BINDING SITES.
    Category: Function, Interaction, Structure.
    Source: UniProtKB/Swiss-Prot (reviewed).
  18. 18
    "Polymorphisms in human CYP2C8 decrease metabolism of the anticancer drug paclitaxel and arachidonic acid."
    Dai D., Zeldin D.C., Blaisdell J.A., Chanas B., Coulter S.J., Ghanayem B.I., Goldstein J.A.
    Pharmacogenetics 11:597-607(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS LYS-139; PHE-269 AND ARG-399.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  19. 19
    "CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6alpha-hydroxylase activity in human liver microsomes."
    Bahadur N., Leathart J.B., Mutch E., Steimel-Crespi D., Dunn S.A., Gilissen R., Houdt J.V., Hendrickx J., Mannens G., Bohets H., Williams F.M., Armstrong M., Crespi C.L., Daly A.K.
    Biochem. Pharmacol. 64:1579-1589(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS LYS-139; MET-264; PHE-269; SER-390 AND ARG-399.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  20. 20
    "Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population."
    Solus J.F., Arietta B.J., Harris J.R., Sexton D.P., Steward J.Q., McMunn C., Ihrie P., Mehall J.M., Edwards T.L., Dawson E.P.
    Pharmacogenomics 5:895-931(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS LYS-139; MET-264; PHE-269 AND ARG-399.
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 10 other entries.

  21. 21
    "Functional characterization of 12 allelic variants of CYP2C8 by assessment of paclitaxel 6alpha-hydroxylation and amodiaquine N-deethylation."
    Tsukada C., Saito T., Maekawa M., Mano N., Oda A., Hirasawa N., Hiratsuka M.
    Drug Metab. Pharmacokinet. 30:366-373(2015) [PubMed] [Europe PMC] [Abstract]
    Cited for: CHARACTERIZATION OF VARIANTS LYS-139; SER-171; GLY-186; MET-223; PRO-238; ARG-247; MET-264; PHE-269; ASN-383; ARG-399 AND VAL-461 DEL, FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES.
    Category: Function, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  22. 22
    "Polymorphism in CYP2C8 is associated with reduced plasma concentrations of repaglinide."
    Niemi M., Leathart J.B., Neuvonen M., Backman J.T., Daly A.K., Neuvonen P.J.
    Clin. Pharmacol. Ther. 74:380-387(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Associated with OTHER: reduced plasma concentrations of repaglinide.Imported, Associated with OTHER: repaglinide pharmacology.Imported.
    Source: GAD:120916, GAD:120912.

    This publication is mapped to 4 other entries.

  23. 23
    "Allelic variants of cytochromes P450 2C modify the risk for acute myocardial infarction."
    Yasar U., Bennet A.M., Eliasson E., Lundgren S., Wiman B., De Faire U., Rane A.
    Pharmacogenetics 13:715-720(2003) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Associated with CARDIOVASCULAR: myocardial infarct.Imported.
    Source: GAD:120926.

    This publication is mapped to 22 other entries.

  24. 24
    "Interindividual variability in ibuprofen pharmacokinetics is related to interaction of cytochrome P450 2C8 and 2C9 amino acid polymorphisms."
    Garcia-Martin E., Martinez C., Tabares B., Frias J., Agundez J.A.
    Clin. Pharmacol. Ther. 76:119-127(2004) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Associated with PHARMACOGENOMIC: ibuprofen clearance.Imported.
    Source: GAD:120917.

    This publication is mapped to 4 other entries.

  25. 25
    "Single nucleotide polymorphisms in the CYP2J2 and CYP2C8 genes and the risk of hypertension."
    King L.M., Gainer J.V., David G.L., Dai D., Goldstein J.A., Brown N.J., Zeldin D.C.
    Pharmacogenet. Genomics 15:7-13(2005) [PubMed] [Europe PMC] [Abstract]
    Category: Pathology & Biotech.
    Annotation: Associated with CARDIOVASCULAR: hypertension.Imported.
    Source: GAD:120923.

    This publication is mapped to 7 other entries.

1 to 25 of 36  Show