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Reviewed, UniProtKB/Swiss-Prot P10596 (INV4_YEAST)

Last modified October 13, 2009. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Invertase 4
    EC=3.2.1.26
Alternative name(s):
    Beta-fructofuranosidase 4
    Saccharase
Gene names
Name: SUC4
OrganismSaccharomyces cerevisiae (Baker's yeast)
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

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Protein attributes

Sequence length532 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.

Sequence similarities

Belongs to the glycosyl hydrolase 32 family.

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Ontologies

Keywords
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionbeta-fructofuranosidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919
Chain20 – 532513Invertase 4
PRO_0000033402

Regions

Region39 – 424Substrate binding By similarity
Region102 – 1032Substrate binding By similarity
Region170 – 1712Substrate binding By similarity

Sites

Active site421 By similarity
Binding site601Substrate By similarity
Binding site2231Substrate By similarity
Binding site3111Substrate By similarity

Amino acid modifications

Glycosylation231N-linked (GlcNAc...) Potential
Glycosylation641N-linked (GlcNAc...) Potential
Glycosylation971N-linked (GlcNAc...) Potential
Glycosylation1111N-linked (GlcNAc...) Potential
Glycosylation1121N-linked (GlcNAc...) Potential
Glycosylation1181N-linked (GlcNAc...) Potential
Glycosylation1651N-linked (GlcNAc...) Potential
Glycosylation2661N-linked (GlcNAc...) Potential
Glycosylation2751N-linked (GlcNAc...) Potential
Glycosylation3561N-linked (GlcNAc...) Potential
Glycosylation3691N-linked (GlcNAc...) Potential
Glycosylation3841N-linked (GlcNAc...) Potential
Glycosylation3981N-linked (GlcNAc...) Potential
Glycosylation5121N-linked (GlcNAc...) Potential

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Sequences

Sequence LengthMass (Da)Tools
P10596-1 [UniParc].

Last modified July 1, 1989. Version 1.
Checksum: A56EA2E3A49125EB

FASTA53260,575
        10         20         30         40         50         60 
MLLQAFIFLL AGFAAKISAL MTNETSDRPL VHFTPNKGWM NDPNGLWYDA KEGKWHLYFQ 

        70         80         90        100        110        120 
YNPNDTVWGL PLFWGHATSN DLTHWQDEPV AIAPKRNDSG AYSGSMVIDH NNTSEFFNDT 

       130        140        150        160        170        180 
VDPRQRCVAI WTYNTPESEE QYISYSLDGG YTFTEYQKNP VLAANSTQFR DPKVFWYEPS 

       190        200        210        220        230        240 
QKWIMTAAKS QDYKIEIYSS DDLKSWKLES AFANEGFLGY QYECPGLIEV PTEQDPSKSH 

       250        260        270        280        290        300 
WVMFISINPG APAGGSFNQY FVGSFNGTHF EAYDNQSRVV DFGKDYYALQ TFFNTDPTYG 

       310        320        330        340        350        360 
SALGIAWASN WEYSAFVPTN PWRSSMSLVR KFSLNTEYQA NPETELINLK AEPILNISNA 

       370        380        390        400        410        420 
GPWLHFASNS TLTKANSFSV DLSNSTGTLE FELVYAVNTT QSVSKSVFSD LSLWFKGLED 

       430        440        450        460        470        480 
PEEYLRMGFE ASASSFFLDR GNSKVKFVKE NPYFTNRMSV NNQPFKSEND LSYYKVYGLL 

       490        500        510        520        530 
DQNILELYFN DGDVVSTNTY FMTTGNALGS VNMTTGVDNL FYIDKFQVRE VK

« Hide

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References

[1]"Structural analysis of the 5' regions of yeast SUC genes revealed analogous palindromes in SUC, MAL and GAL."
Hohmann S., Gozalbo D.
Mol. Gen. Genet. 211:446-454(1988) [PubMed: 2835632] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-73.
[2]Hohmann S.
Submitted (NOV-1988) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+Additional computationally mapped references.

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Cross-references

Sequence databases

X07572 Genomic DNA. Translation: CAA30459.1.
PIRS27373.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGP10596.

Protein family/group databases

CAZyGH32. Glycoside Hydrolase Family 32.

Genome annotation databases

EnsemblYIL162W; YIL162W; YIL162W; Saccharomyces cerevisiae. [Genome view]

Organism-specific databases

SGDS000029533. SUC4.

Enzyme and pathway databases

BRENDA3.2.1.26. 250.

Gene expression databases

ArrayExpressP10596.
GenevestigatorP10596.
GermOnlineYIL162W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR001362. Glyco_hydro_32.
IPR018053. Glyco_hydro_32_AS.
IPR013189. Glyco_hydro_32_C.
IPR013148. Glyco_hydro_32_N.
[Graphical view]
PfamPF08244. Glyco_hydro_32C. 1 hit.
PF00251. Glyco_hydro_32N. 1 hit.
[Graphical view]
SMARTSM00640. Glyco_32. 1 hit.
[Graphical view]
PROSITEPS00609. GLYCOSYL_HYDROL_F32. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameINV4_YEAST
AccessionPrimary (citable) accession number: P10596
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: October 13, 2009
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents