ID   DHGA_BACME              Reviewed;         261 AA.
AC   P10528;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   16-JUN-2009, entry version 56.
DE   RecName: Full=Glucose 1-dehydrogenase A;
DE            EC=1.1.1.47;
GN   Name=gdhA;
OS   Bacillus megaterium.
OC   Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1404;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=M1286;
RX   MEDLINE=88271315; PubMed=3134196;
RX   DOI=10.1111/j.1432-1033.1988.tb14124.x;
RA   Heilmann H.J., Maegert H.-J., Gassen H.G.;
RT   "Identification and isolation of glucose dehydrogenase genes of
RT   Bacillus megaterium M1286 and their expression in Escherichia coli.";
RL   Eur. J. Biochem. 174:485-490(1988).
CC   -!- CATALYTIC ACTIVITY: Beta-D-glucose + NAD(P)(+) = D-glucono-1,5-
CC       lactone + NAD(P)H.
CC   -!- SUBUNIT: Homotetramer.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; X12370; CAA30931.1; -; Genomic_DNA.
DR   PIR; S00812; S00812.
DR   HSSP; P40288; 1GEE.
DR   SMR; P10528; 1-261.
DR   BRENDA; 1.1.1.47; 325.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0047936; F:glucose 1-dehydrogenase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002198; DH_sc/Rdtase_SDR.
DR   InterPro; IPR002347; Glc/ribitol_DH.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR19410; ADH_short_C2; 1.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   PROSITE; PS00061; ADH_SHORT; 1.
PE   3: Inferred from homology;
KW   NADP; Oxidoreductase.
FT   CHAIN         1    261       Glucose 1-dehydrogenase A.
FT                                /FTId=PRO_0000054613.
FT   NP_BIND      11     35       NADP (By similarity).
FT   ACT_SITE    158    158       Proton acceptor (By similarity).
FT   BINDING     145    145       Substrate (By similarity).
SQ   SEQUENCE   261 AA;  28187 MW;  6FADDA3968DC417C CRC64;
     MYTDLKDKVV VITGGSTGLG RAMAVRFGQE EAKVVINYYN NEEEALDAKK EVEEAGGQAI
     IVQGDVTKEE DVVNLVQTAI KEFGTLDVMI NNAGVENPVP SHELSLDNWN KVIDTNLTGA
     FLGSREAIKY FVENDIKGNV INMSSVHEMI PWPLFVHYAA SKGGMKLMTE TLALEYAPKG
     IRVNNIGPGA MNTPINAEKF ADPEQRADVE SMIPMGYIGK PEEVAAVAAF LASSQASYVT
     GITLFADGGM TKYPSFQAGR G
//