ID   PCP_HAEIN               Reviewed;         155 AA.
AC   P10325;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 2.
DT   27-MAR-2024, entry version 123.
DE   RecName: Full=Outer membrane lipoprotein pcp;
DE   AltName: Full=15 kDa lipoprotein;
DE   AltName: Full=PAL cross-reacting lipoprotein;
DE   Flags: Precursor;
GN   Name=pcp; Synonyms=lpp; OrderedLocusNames=HI_1579;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], DIACYLGLYCEROL AT CYS-19, AND
RP   PALMITOYLATION AT CYS-19.
RX   PubMed=2828309; DOI=10.1128/jb.170.2.489-498.1988;
RA   Deich R.A., Metcalf B.J., Finn C.W., Farley J.E., Green B.A.;
RT   "Cloning of genes encoding a 15,000-dalton peptidoglycan-associated outer
RT   membrane lipoprotein and an antigenically related 15,000-dalton protein
RT   from Haemophilus influenzae.";
RL   J. Bacteriol. 170:489-498(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Lipid-anchor.
CC   -!- SIMILARITY: Belongs to the Pcp/SlyB lipoprotein family. {ECO:0000305}.
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DR   EMBL; M18877; AAA24938.1; -; mRNA.
DR   EMBL; L42023; AAC23228.1; -; Genomic_DNA.
DR   PIR; I64130; I64130.
DR   RefSeq; NP_439725.1; NC_000907.1.
DR   AlphaFoldDB; P10325; -.
DR   SMR; P10325; -.
DR   STRING; 71421.HI_1579; -.
DR   EnsemblBacteria; AAC23228; AAC23228; HI_1579.
DR   KEGG; hin:HI_1579; -.
DR   PATRIC; fig|71421.8.peg.1652; -.
DR   eggNOG; COG3133; Bacteria.
DR   HOGENOM; CLU_090265_3_1_6; -.
DR   OrthoDB; 5298161at2; -.
DR   PhylomeDB; P10325; -.
DR   BioCyc; HINF71421:G1GJ1-1597-MONOMER; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008816; Gly_zipper_2TM_dom.
DR   PANTHER; PTHR35603; -; 1.
DR   PANTHER; PTHR35603:SF1; OUTER MEMBRANE LIPOPROTEIN SLYB; 1.
DR   Pfam; PF05433; Rick_17kDa_Anti; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   1: Evidence at protein level;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal.
FT   SIGNAL          1..18
FT   CHAIN           19..155
FT                   /note="Outer membrane lipoprotein pcp"
FT                   /id="PRO_0000018159"
FT   LIPID           19
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303,
FT                   ECO:0000269|PubMed:2828309"
FT   LIPID           19
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303,
FT                   ECO:0000269|PubMed:2828309"
FT   CONFLICT        135..143
FT                   /note="CSLVAEFVF -> VAGRRVRI (in Ref. 1; AAA24938)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   155 AA;  15425 MW;  D7880327FCF0C985 CRC64;
     MKKTNMALAL LVAFSVTGCA NTDIFSGDVY SASQAKEARS ITYGTIVSVR PVKIQADNQG
     VVGTLGGGAL GGIAGSTIGG GRGQAIAAVV GAIGGAIAGS KIEEKMSQVN GAELVIKKDD
     GQEIVVVQKA DSSFCSLVAE FVFVGGGSSL NVSVL
//