P10325 (PCP_HAEIN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Outer membrane lipoprotein pcp

Alternative name(s):
15 kDa lipoprotein
PAL cross-reacting lipoprotein

Gene names

Name:	pcp
Synonyms:	lpp
Ordered Locus Names:	HI_1579

Organism

Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [Reference proteome] [HAMAP]

Taxonomic identifier

71421 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pasteurellales › Pasteurellaceae › Haemophilus › Haemophilus influenzae

Protein attributes

Sequence length	155 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subcellular location	Cell outer membrane; Lipid-anchor.
Sequence similarities	Belongs to the Pcp/SlyB lipoprotein family.

Ontologies

Keywords
Cellular component	Cell membrane Cell outer membrane Membrane
Domain	Signal
PTM	Lipoprotein Palmitate
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	cell outer membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 18	18
	Chain	19 – 155	137	Outer membrane lipoprotein pcp		PRO_0000018159
Amino acid modifications
	Lipidation	19	1	N-palmitoyl cysteine Ref.1
	Lipidation	19	1	S-diacylglycerol cysteine
Experimental info
	Sequence conflict	135 – 143	9	CSLVAEFVF → VAGRRVRI in AAA24938. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P10325 [UniParc]. Last modified November 1, 1995. Version 2. Checksum: D7880327FCF0C985	FASTA	155	15,425
	10 20 30 40 50 60 MKKTNMALAL LVAFSVTGCA NTDIFSGDVY SASQAKEARS ITYGTIVSVR PVKIQADNQG 70 80 90 100 110 120 VVGTLGGGAL GGIAGSTIGG GRGQAIAAVV GAIGGAIAGS KIEEKMSQVN GAELVIKKDD 130 140 150 GQEIVVVQKA DSSFCSLVAE FVFVGGGSSL NVSVL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning of genes encoding a 15,000-dalton peptidoglycan-associated outer membrane lipoprotein and an antigenically related 15,000-dalton protein from Haemophilus influenzae." Deich R.A., Metcalf B.J., Finn C.W., Farley J.E., Green B.A. J. Bacteriol. 170:489-498(1988) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], DIACYLGLYCEROL AT CYS-19, PALMITOYLATION AT CYS-19.
[2]	"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd." Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I. , Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C. Science 269:496-512(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51907 / DSM 11121 / KW20 / Rd.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M18877 mRNA. Translation: AAA24938.1. L42023 Genomic DNA. Translation: AAC23228.1.
PIR	I64130.
RefSeq	NP_439725.1. NC_000907.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	71421.HI1579.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAC23228; AAC23228; HI_1579.
GeneID	950439.
KEGG	hin:HI1579.
PATRIC	20191889. VBIHaeInf48452_1652.
Phylogenomic databases
eggNOG	COG3133.
KO	K06077.
OMA	TLAGCVN.
ProtClustDB	CLSK870155.
Family and domain databases
InterPro	IPR008816. Gly_zipper_2TM_dom. [Graphical view]
Pfam	PF05433. Rick_17kDa_Anti. 1 hit. [Graphical view]
PROSITE	PS51257. PROKAR_LIPOPROTEIN. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PCP_HAEIN

Accession

Primary (citable) accession number: P10325

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
Last sequence update:	November 1, 1995
Last modified:	May 1, 2013
This is version 91 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program