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Protein

Outer membrane protein P6

Gene

pal

Organism
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Thought to play a role in bacterial envelope integrity. Links the outer membrane to the peptidoglycan layer.

Names & Taxonomyi

Protein namesi
Recommended name:
Outer membrane protein P6
Short name:
OMP P6
Alternative name(s):
15 kDa peptidoglycan-associated lipoprotein
Short name:
PC protein
Gene namesi
Name:pal
Synonyms:ompP6
Ordered Locus Names:HI_0381
OrganismiHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
Taxonomic identifieri71421 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus
Proteomesi
  • UP000000579 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

Pathology & Biotechi

Protein family/group databases

Allergomei7668. Hae in P6.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19Add BLAST19
ChainiPRO_000002012320 – 153Outer membrane protein P6Add BLAST134

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi20N-palmitoyl cysteinePROSITE-ProRule annotation1 Publication1
Lipidationi20S-diacylglycerol cysteinePROSITE-ProRule annotation1 Publication1

Keywords - PTMi

Lipoprotein, Palmitate

Interactioni

Protein-protein interaction databases

STRINGi71421.HI0381.

Structurei

Secondary structure

1153
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi26 – 29Combined sources4
Helixi41 – 44Combined sources4
Turni45 – 47Combined sources3
Beta strandi50 – 52Combined sources3
Helixi62 – 77Combined sources16
Beta strandi83 – 88Combined sources6
Beta strandi91 – 93Combined sources3
Helixi95 – 115Combined sources21
Helixi120 – 122Combined sources3
Beta strandi123 – 127Combined sources5
Turni129 – 131Combined sources3
Helixi140 – 146Combined sources7
Beta strandi147 – 152Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2AIZNMR-P20-153[»]
ProteinModelPortaliP10324.
SMRiP10324.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP10324.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 153OmpA-likePROSITE-ProRule annotationAdd BLAST114

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni55 – 56Peptidoglycan binding2
Regioni97 – 101Peptidoglycan binding5

Sequence similaritiesi

Belongs to the OmpA family. Pal subfamily.Curated
Contains 1 OmpA-like domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105KCK. Bacteria.
COG2885. LUCA.
KOiK03640.
OMAiSTESCWS.
PhylomeDBiP10324.

Family and domain databases

CDDicd07185. OmpA_C-like. 1 hit.
Gene3Di3.30.1330.60. 1 hit.
InterProiIPR006664. OMP_bac.
IPR006665. OmpA-like.
IPR006690. OMPA-like_CS.
IPR014169. Pal_lipo.
[Graphical view]
PfamiPF00691. OmpA. 1 hit.
[Graphical view]
PRINTSiPR01021. OMPADOMAIN.
SUPFAMiSSF103088. SSF103088. 1 hit.
TIGRFAMsiTIGR02802. Pal_lipo. 1 hit.
PROSITEiPS01068. OMPA_1. 1 hit.
PS51123. OMPA_2. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P10324-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKFVKSLLV AGSVAALAAC SSSNNDAAGN GAAQTFGGYS VADLQQRYNT
60 70 80 90 100
VYFGFDKYDI TGEYVQILDA HAAYLNATPA AKVLVEGNTD ERGTPEYNIA
110 120 130 140 150
LGQRRADAVK GYLAGKGVDA GKLGTVSYGE EKPAVLGHDE AAYSKNRRAV

LAY
Length:153
Mass (Da):16,108
Last modified:July 1, 1989 - v1
Checksum:i3DF358122EF17A11
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M19391 Genomic DNA. Translation: AAA24994.1.
M18878 Genomic DNA. Translation: AAA24940.1.
L42023 Genomic DNA. Translation: AAC22039.1.
PIRiA28543.
RefSeqiNP_438542.1. NC_000907.1.
WP_005652235.1. NC_000907.1.

Genome annotation databases

EnsemblBacteriaiAAC22039; AAC22039; HI_0381.
GeneIDi949485.
KEGGihin:HI0381.
PATRICi20189311. VBIHaeInf48452_0399.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M19391 Genomic DNA. Translation: AAA24994.1.
M18878 Genomic DNA. Translation: AAA24940.1.
L42023 Genomic DNA. Translation: AAC22039.1.
PIRiA28543.
RefSeqiNP_438542.1. NC_000907.1.
WP_005652235.1. NC_000907.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2AIZNMR-P20-153[»]
ProteinModelPortaliP10324.
SMRiP10324.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi71421.HI0381.

Protein family/group databases

Allergomei7668. Hae in P6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC22039; AAC22039; HI_0381.
GeneIDi949485.
KEGGihin:HI0381.
PATRICi20189311. VBIHaeInf48452_0399.

Phylogenomic databases

eggNOGiENOG4105KCK. Bacteria.
COG2885. LUCA.
KOiK03640.
OMAiSTESCWS.
PhylomeDBiP10324.

Miscellaneous databases

EvolutionaryTraceiP10324.

Family and domain databases

CDDicd07185. OmpA_C-like. 1 hit.
Gene3Di3.30.1330.60. 1 hit.
InterProiIPR006664. OMP_bac.
IPR006665. OmpA-like.
IPR006690. OMPA-like_CS.
IPR014169. Pal_lipo.
[Graphical view]
PfamiPF00691. OmpA. 1 hit.
[Graphical view]
PRINTSiPR01021. OMPADOMAIN.
SUPFAMiSSF103088. SSF103088. 1 hit.
TIGRFAMsiTIGR02802. Pal_lipo. 1 hit.
PROSITEiPS01068. OMPA_1. 1 hit.
PS51123. OMPA_2. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPAL_HAEIN
AccessioniPrimary (citable) accession number: P10324
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: November 2, 2016
This is version 124 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Haemophilus influenzae
    Haemophilus influenzae (strain Rd): entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.