SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P10292

- ITR4_CUCSA

UniProt

P10292 - ITR4_CUCSA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Trypsin inhibitor 4
Gene
N/A
Organism
Cucumis sativus (Cucumber)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Inhibits trypsin.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sitei5 – 62Reactive bond

GO - Molecular functioni

  1. serine-type endopeptidase inhibitor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Protease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI07.015.

Names & Taxonomyi

Protein namesi
Recommended name:
Trypsin inhibitor 4
Alternative name(s):
CSTI-IV
Trypsin inhibitor IV
OrganismiCucumis sativus (Cucumber)
Taxonomic identifieri3659 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsCucurbitalesCucurbitaceaeBenincaseaeCucumis

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Peptidei1 – 3030Trypsin inhibitor 4
PRO_0000044377Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi3 ↔ 20 By similarity
Disulfide bondi10 ↔ 22 By similarity
Disulfide bondi16 ↔ 29 By similarity

Keywords - PTMi

Disulfide bond

Structurei

3D structure databases

ProteinModelPortaliP10292.
SMRiP10292. Positions 2-30.

Family & Domainsi

Domaini

The presence of a 'disulfide through disulfide knot' structurally defines this protein as a knottin By similarity.

Sequence similaritiesi

Keywords - Domaini

Knottin

Family and domain databases

InterProiIPR000737. Prot_inh_squash.
IPR011052. Proteinase_amylase_inhib_dom.
[Graphical view]
PfamiPF00299. Squash. 1 hit.
[Graphical view]
PRINTSiPR00293. SQUASHINHBTR.
SUPFAMiSSF57027. SSF57027. 1 hit.
PROSITEiPS00286. SQUASH_INHIBITOR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P10292-1 [UniParc]FASTAAdd to Basket

« Hide

MMCPRILMKC KHDSDCLPGC VCLEHIEYCG                         30
Length:30
Mass (Da):3,429
Last modified:July 1, 1989 - v1
Checksum:i7A4B870E7D2A088F
GO

Cross-referencesi

3D structure databases

ProteinModelPortali P10292.
SMRi P10292. Positions 2-30.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

MEROPSi I07.015.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR000737. Prot_inh_squash.
IPR011052. Proteinase_amylase_inhib_dom.
[Graphical view ]
Pfami PF00299. Squash. 1 hit.
[Graphical view ]
PRINTSi PR00293. SQUASHINHBTR.
SUPFAMi SSF57027. SSF57027. 1 hit.
PROSITEi PS00286. SQUASH_INHIBITOR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The squash family of serine proteinase inhibitors. Amino acid sequences and association equilibrium constants of inhibitors from squash, summer squash, zucchini, and cucumber seeds."
    Wieczorek M., Otlewski J., Cook J., Parks K., Leluk J., Wilimowska-Pelc A., Polanowski A., Wilusz T., Laskowski M. Jr.
    Biochem. Biophys. Res. Commun. 126:646-652(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE.
    Tissue: Seed.

Entry informationi

Entry nameiITR4_CUCSA
AccessioniPrimary (citable) accession number: P10292
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: April 16, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi