Reviewed,
UniProtKB/Swiss-Prot P10228 (VGLC_HHV11)
Last modified
June 16, 2009.
Version 54.
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Glycoprotein C | ||||
| Gene names |
| ||||
| Organism | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) [Complete proteome] | ||||
| Taxonomic identifier | 10299 [NCBI] | ||||
| Taxonomic lineage | Viruses › dsDNA viruses, no RNA stage › Herpesvirales › Herpesviridae › Alphaherpesvirinae › Simplexvirus | ||||
| Virus host | Homo sapiens (Human) [TaxID: 9606] |
Protein attributes
| Sequence length | 511 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Subcellular location | Virion membrane; Single-pass membrane protein Potential. |
| Miscellaneous | There are seven external glycoproteins in HSV-1 and 2: gH, gB, gC, gG, gD, gI, and gE. |
| Sequence similarities | Belongs to the herpesviridae glycoprotein C family. Contains 1 Ig-like (immunoglobulin-like) domain. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Membrane Virion |
| Domain | Immunoglobulin domain Signal Transmembrane |
| PTM | Glycoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | signal transduction Inferred from electronic annotation. Source: InterPro |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 24 | 24 | Potential | ||||||
| Chain | 25 – 511 | 487 | Glycoprotein C | PRO_0000038197 | |||||
Regions | |||||||||
| Transmembrane | 481 – 497 | 17 | Potential | ||||||
| Domain | 267 – 359 | 93 | Ig-like | ||||||
Amino acid modifications | |||||||||
| Glycosylation | 42 | 1 | N-linked (GlcNAc...); by host Potential | ||||||
| Glycosylation | 70 | 1 | N-linked (GlcNAc...); by host Potential | ||||||
| Glycosylation | 74 | 1 | N-linked (GlcNAc...); by host Potential | ||||||
| Glycosylation | 108 | 1 | N-linked (GlcNAc...); by host Potential | ||||||
| Glycosylation | 148 | 1 | N-linked (GlcNAc...); by host Potential | ||||||
| Glycosylation | 181 | 1 | N-linked (GlcNAc...); by host Potential | ||||||
| Glycosylation | 197 | 1 | N-linked (GlcNAc...); by host Potential | ||||||
| Glycosylation | 362 | 1 | N-linked (GlcNAc...); by host Potential | ||||||
Sequences
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References
| [1] | "The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1." McGeoch D.J., Dalrymple M.A., Davison A.J., Dolan A., Frame M.C., McNab D., Perry L.J., Scott J.E., Taylor P. J. Gen. Virol. 69:1531-1574(1988) [PubMed: 2839594] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| X14112 Genomic DNA. Translation: CAA32294.1. | |
| PIR | VGBEF4. H30088. |
| RefSeq | NP_044646.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 2703410. |
Family and domain databases | |
| InterPro | IPR001038. GA_GC. IPR007110. Ig-like. IPR013783. Ig-like_fold. [Graphical view] |
| Gene3D | G3DSA:2.60.40.10. Ig-like_fold. 1 hit. |
| Pfam | PF02124. Marek_A. 1 hit. [Graphical view] |
| PRINTS | PR00668. GLYCPROTEINC. |
| PROSITE | PS50835. IG_LIKE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | VGLC_HHV11 | ||||||||
| Accession | Primary (citable) accession number: P10228 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | Virus (Virus annotation project) | ||||||||

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