P10221 (V120_HHV11) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Capsid assembly protein UL37

Gene names

Name:

UL37

Organism

Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) [Reference proteome]

Taxonomic identifier

10299 [NCBI]

Taxonomic lineage

Viruses › dsDNA viruses, no RNA stage › Herpesvirales › Herpesviridae › Alphaherpesvirinae › Simplexvirus › Human herpesvirus 1

Virus host

Homo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length	1123 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Interacts with the large tegument protein. Ref.2
Subcellular location	Virion tegument Potential.
Sequence similarities	Belongs to the herpesviridae HHV-1 UL37 family.

Ontologies

Keywords
Cellular component	Virion Virion tegument
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	virion assembly Inferred from electronic annotation. Source: InterPro
Cellular_component	viral tegument Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1123	1123	Capsid assembly protein UL37		PRO_0000116044

Sequences

	Sequence		Length	Mass (Da)
	P10221 [UniParc]. Last modified July 1, 1989. Version 1. Checksum: 18425792B4D7EC9D	FASTA	1,123	120,556
	10 20 30 40 50 60 MADRGLPSEA PVVTTSPAGP PSDGPMQRLL ASLAGLRQPP TPTAETANGA DDPAFLATAK 70 80 90 100 110 120 LRAAMAAFLL SGTAIAPADA RDCWRPLLEH LCALHRAHGL PETALLAENL PGLLVHRLVV 130 140 150 160 170 180 ALPEAPDQAF REMEVIKDTI LAVTGSDTSH ALDSAGLRTA AALGPVRVRQ CAVEWIDRWQ 190 200 210 220 230 240 TVTKSCLAMS PRTSIEALGE TSLKMAPVPL GQPSANLTTP AYSLLFPAPF VQEGLRFLAL 250 260 270 280 290 300 VSNRVTLFSA HLQRIDDATL TPLTRALFTL ALVDEYLTTP ERGAVVPPPL LAQFQHTVRE 310 320 330 340 350 360 IDPAIMIPPL EANKMVRSRE EVRVSTALSR VSPRSACAPP GTLMARVRTD VAVFDPDVPF 370 380 390 400 410 420 LSSSALAVFQ PAVSSLLQLG EQPSAGAQQR LLALLQQTWT LIQNTNSPSV VINTLIDAGF 430 440 450 460 470 480 TPSHCTHYLS ALEGFLAAGV PARTPTGHGL GEVQQLFGCI ALAGSNVFGL AREYGYYANY 490 500 510 520 530 540 VKTFRRVQGA SEHTHGRLCE AVGLSGGVLS QTLARIMGPA VPTEHLASLR RALVGEFETA 550 560 570 580 590 600 ERRFSSGQPS LLRETALIWI DVYGQTHWDI TPTTPATPLS ALLPVGQPSH APSVHLAAAT 610 620 630 640 650 660 QIRFPALEGI HPNVLADPGF VPYVLALVVG DALRATCSAA YLPRPVEFAL RVLAWARDFG 670 680 690 700 710 720 LGYLPTVEGH RTKLGALITL LEPAARGGLG PTMQMADNIE QLLRELYVIS RGAVEQLRPL 730 740 750 760 770 780 VQLQPPPPPE VGTSLLLISM YALAARGVLQ DLAERADPLI RQLEDAIVLL RLHMRTLSAF 790 800 810 820 830 840 FECRFESDGR RLYAVVGDTP DRLGPWPPEA MGDAVSQYCS MYHDAKRALV ASLASLRSVI 850 860 870 880 890 900 TETTAHLGVC DELAAQVSHE DNVLAVVRRE IHGFLSVVSG IHARASKLLS GDQVPGFCFM 910 920 930 940 950 960 GQFLARWRRL SACYQAARAA AGPEPVAEFV QELHDTWKGL QTERAVVVAP LVSSADQRAA 970 980 990 1000 1010 1020 AIREVMAHAP EDAPPQSPAA DRVVLTSRRD LGAWGDYSLG PLGQTTAVPD SVDLSRQGLA 1030 1040 1050 1060 1070 1080 VTLSMDWLLM NELLRVTDGV FRASAFRPLA GPESPRDLEV RDAGNSLPAP MPMDAQKPEA 1090 1100 1110 1120 YGHGPRQADR EGAPHSNTPV EDDEMIPEDT VAPPTDLPLT SYQ

References

[1]	"The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1." McGeoch D.J., Dalrymple M.A., Davison A.J., Dolan A., Frame M.C., McNab D., Perry L.J., Scott J.E., Taylor P. J. Gen. Virol. 69:1531-1574(1988) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Localization of herpes simplex virus type 1 UL37 in the Golgi complex requires UL36 but not capsid structures." Desai P., Sexton G.L., Huang E., Person S. J. Virol. 82:11354-11361(2008) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH THE LARGE TEGUMENT PROTEIN. Strain: KOS.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X14112 Genomic DNA. Translation: CAA32312.1.
PIR	WMBEH7. A30088.
RefSeq	NP_044639.1. NC_001806.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-6732722.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2703358.
Phylogenomic databases
ProtClustDB	PHA3173.
Family and domain databases
InterPro	IPR005655. Herpes_UL37_HHV-3-rel. [Graphical view]
Pfam	PF03970. Herpes_UL37_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

V120_HHV11

Accession

Primary (citable) accession number: P10221

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 1989
Last sequence update:	July 1, 1989
Last modified:	April 3, 2013
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program