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P10216

- UL32_HHV11

UniProt

P10216 - UL32_HHV11

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Protein
Packaging protein UL32
Gene
UL32
Organism
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Plays a role in efficient localization of neo-synthesized capsids to nuclear replication compartments, thereby controlling cleavage and packaging of virus genomic DNA.2 Publications

Names & Taxonomyi

Protein namesi
Recommended name:
Packaging protein UL32
Gene namesi
Name:UL32
OrganismiHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Taxonomic identifieri10299 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
ProteomesiUP000009294: Genome

Subcellular locationi

Host cytoplasm. Host nucleus
Note: Mainly cytoplasmic in transfected cell culture.1 Publication

GO - Cellular componenti

  1. host cell cytoplasm Source: UniProtKB-SubCell
  2. host cell nucleus Source: UniProtKB-SubCell
  3. viral envelope Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm, Host nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 596596Packaging protein UL32
PRO_0000116014Add
BLAST

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiIPR002597. Herpes_env.
[Graphical view]
PfamiPF01673. Herpes_env. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P10216-1 [UniParc]FASTAAdd to Basket

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MATSPPGVLA SVAVCEESPG SSWKAGAFER AYVAFDPSLL ALNEALCAEL    50
LTASHVIGVP PVGTLDEDVA ADVVTAPSRA RGGAGDGGGS GGRGGPRNPP 100
PDPCGEGLLD TGPFSAAAID TFALDRPCLV CRTIELYKQT YRLSPQWVAD 150
YAFLCAKCLG APHCAASIFV AAFEFVYVMD RHFLRTKKAT LVGSFARFAL 200
TINDIHRHFF LHCCFRTDGG VPGRHAQKQP KPSPSPGAAK VQYSNYSFLA 250
QSATRALIGT LASGGEEGAG SAAGSGTQPS LTTALMNWKD CARLLDCTEG 300
RRGGGDSCCT RAAARNGEFE TVAGDREPEE SPDTWAYADL VLLLLAGTPA 350
VWESGPQLRA AAEARRATVR QSWEAHRGAR TRDVAPRFAQ FTEPDAQPDL 400
DLGPLMATVL KHGRGRGRTG GECLLCNLLL VRAYWLALRR LRASVVRYSE 450
NNTSLFDCIV PVVDQLEADP ETQPGDGGRF VSLLRAAGPE AIFKHMFCDP 500
MCAITEMEVD PWVLFGHPPA THPDELLLHK AKLACGNEFE GRVCIALRAL 550
IYTFKTYQVF VPKPTALATF VREAGALLRR HSISLLSLEH TLCTYV 596
Length:596
Mass (Da):63,950
Last modified:July 1, 1989 - v1
Checksum:i6E650D5EE9CB09B8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14112 Genomic DNA. Translation: CAA32307.1.
PIRiE30085. WMBEH2.
RefSeqiNP_044634.1. NC_001806.1.

Genome annotation databases

GeneIDi2703352.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14112 Genomic DNA. Translation: CAA32307.1 .
PIRi E30085. WMBEH2.
RefSeqi NP_044634.1. NC_001806.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2703352.

Family and domain databases

InterProi IPR002597. Herpes_env.
[Graphical view ]
Pfami PF01673. Herpes_env. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1."
    McGeoch D.J., Dalrymple M.A., Davison A.J., Dolan A., Frame M.C., McNab D., Perry L.J., Scott J.E., Taylor P.
    J. Gen. Virol. 69:1531-1574(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Properties of the protein encoded by the UL32 open reading frame of herpes simplex virus 1."
    Chang Y.E., Poon A.P., Roizman B.
    J. Virol. 70:3938-3946(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  3. "The herpes simplex virus type 1 cleavage/packaging protein, UL32, is involved in efficient localization of capsids to replication compartments."
    Lamberti C., Weller S.K.
    J. Virol. 72:2463-2473(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiUL32_HHV11
AccessioniPrimary (citable) accession number: P10216
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Caution

Was originally thought to be an envelope glycoprotein.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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