Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P10201

- UL17_HHV11

UniProt

P10201 - UL17_HHV11

Protein

Virion-packaging protein UL17

Gene

UL17

Organism
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 54 (01 Oct 2014)
      Sequence version 1 (01 Jul 1989)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Plays a role at the late stage in the encapsidation of viral DNA, assuring correct genome cleavage and presumably stabilizing capsids that contain full-lengtht viral genomes.

    GO - Biological processi

    1. DNA packaging Source: InterPro
    2. viral release from host cell Source: UniProtKB-KW

    Keywords - Biological processi

    Viral genome packaging, Virus exit from host cell

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Virion-packaging protein UL17
    Gene namesi
    Name:UL17
    OrganismiHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
    Taxonomic identifieri10299 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
    Virus hostiHomo sapiens (Human) [TaxID: 9606]
    ProteomesiUP000009294: Genome

    Subcellular locationi

    GO - Cellular componenti

    1. host cell nucleus Source: UniProtKB-SubCell
    2. viral capsid Source: UniProtKB-KW

    Keywords - Cellular componenti

    Capsid protein, Host nucleus, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 703703Virion-packaging protein UL17PRO_0000115958Add
    BLAST

    Expressioni

    Keywords - Developmental stagei

    Late protein

    Interactioni

    Subunit structurei

    Heterodimerizes with UL25.

    Protein-protein interaction databases

    DIPiDIP-60386N.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the herpesviridae UL17 family.Curated

    Family and domain databases

    InterProiIPR007640. Herpes_U64.
    [Graphical view]
    PfamiPF04559. Herpes_UL17. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P10201-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNAHLANEVQ TISATARVGP RSLVHVIISS ECLAAAGIPL AALMRGRPGL    50
    GTAANFQVEI QTRAHATGDC TPWCTAFAAY VPADAVGELL APVVPAHPGL 100
    LPRASSAGGL FVSLPVVCDA QGVYDPYAVA ALRLAWGSGA SCARVILFSY 150
    DELVPPNTRY AADSTRIMRV CRHLCRYVAL LGAAAPPAAK EAAAHLSMGL 200
    GESASPRPQP LARPHAGAPA DPPIVGASDP PISPEEQLTA PGGDTTAAQD 250
    VSIAQENEEI LALVQRAVQD VTRRHPVRAR TGRAACGVAS GLRQGALVHQ 300
    AVSGGAMGAA DADAVLAGLE PPGGGRFVAP APHGPGGEDI LNDVLTLTPG 350
    TAKPRSLVEW LDRGWEALAG GDRPDWLWSR RSISVVLRHH YGTKQRFVVV 400
    SYENSVAWGG RRARPPLLSS ALATALTEAC AAERVVRPHQ LSPAGQAELL 450
    LRFPALEVPL RHPRPVLPPF DIAAEVAFTA RIHLACLRAL GQAIRAALQG 500
    GPRISQRLRY DFGPDQRAWL GEVTRRFPIL LENLMRAVEG TAPDAFFHTA 550
    YALAVLAHLG GRGGRGRRVV PLGDDLPARF ADSDGHYVFD YYSTSGDTLR 600
    LNNRPIAVAM DGDVSKREQS KCRFMEAVPS TAPRRVCEQY LPGESYAYLC 650
    LGFNRRLCGI VVFPGGFAFT INIAAYLSLS DPVARAAVLR FCRKVSSGNG 700
    RSR 703
    Length:703
    Mass (Da):74,582
    Last modified:July 1, 1989 - v1
    Checksum:i536DAF5421BD6B4E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X14112 Genomic DNA. Translation: CAA32329.1.
    PIRiH30083. WMBET7.
    RefSeqiNP_044618.1. NC_001806.1.

    Genome annotation databases

    GeneIDi2703388.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X14112 Genomic DNA. Translation: CAA32329.1 .
    PIRi H30083. WMBET7.
    RefSeqi NP_044618.1. NC_001806.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-60386N.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2703388.

    Family and domain databases

    InterProi IPR007640. Herpes_U64.
    [Graphical view ]
    Pfami PF04559. Herpes_UL17. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1."
      McGeoch D.J., Dalrymple M.A., Davison A.J., Dolan A., Frame M.C., McNab D., Perry L.J., Scott J.E., Taylor P.
      J. Gen. Virol. 69:1531-1574(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Allosteric signaling and a nuclear exit strategy: binding of UL25/UL17 heterodimers to DNA-Filled HSV-1 capsids."
      Trus B.L., Newcomb W.W., Cheng N., Cardone G., Marekov L., Homa F.L., Brown J.C., Steven A.C.
      Mol. Cell 26:479-489(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH UL25.

    Entry informationi

    Entry nameiUL17_HHV11
    AccessioniPrimary (citable) accession number: P10201
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1989
    Last sequence update: July 1, 1989
    Last modified: October 1, 2014
    This is version 54 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3