Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P10201 (UL17_HHV11) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 52. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Virion-packaging protein UL17
Gene names
Name:UL17
OrganismHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1) [Reference proteome]
Taxonomic identifier10299 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
Virus hostHomo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length703 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Plays a role at the late stage in the encapsidation of viral DNA, assuring correct genome cleavage and presumably stabilizing capsids that contain full-lengtht viral genomes.

Subunit structure

Heterodimerizes with UL25.

Subcellular location

Virion. Host nucleus.

Sequence similarities

Belongs to the herpesviridae UL17 family.

Ontologies

Keywords
   Biological processViral genome packaging
Virus exit from host cell
   Cellular componentCapsid protein
Host nucleus
Virion
   Developmental stageLate protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processDNA packaging

Inferred from electronic annotation. Source: InterPro

viral release from host cell

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componenthost cell nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

viral capsid

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 703703Virion-packaging protein UL17
PRO_0000115958

Sequences

Sequence LengthMass (Da)Tools
P10201 [UniParc].

Last modified July 1, 1989. Version 1.
Checksum: 536DAF5421BD6B4E

FASTA70374,582
        10         20         30         40         50         60 
MNAHLANEVQ TISATARVGP RSLVHVIISS ECLAAAGIPL AALMRGRPGL GTAANFQVEI 

        70         80         90        100        110        120 
QTRAHATGDC TPWCTAFAAY VPADAVGELL APVVPAHPGL LPRASSAGGL FVSLPVVCDA 

       130        140        150        160        170        180 
QGVYDPYAVA ALRLAWGSGA SCARVILFSY DELVPPNTRY AADSTRIMRV CRHLCRYVAL 

       190        200        210        220        230        240 
LGAAAPPAAK EAAAHLSMGL GESASPRPQP LARPHAGAPA DPPIVGASDP PISPEEQLTA 

       250        260        270        280        290        300 
PGGDTTAAQD VSIAQENEEI LALVQRAVQD VTRRHPVRAR TGRAACGVAS GLRQGALVHQ 

       310        320        330        340        350        360 
AVSGGAMGAA DADAVLAGLE PPGGGRFVAP APHGPGGEDI LNDVLTLTPG TAKPRSLVEW 

       370        380        390        400        410        420 
LDRGWEALAG GDRPDWLWSR RSISVVLRHH YGTKQRFVVV SYENSVAWGG RRARPPLLSS 

       430        440        450        460        470        480 
ALATALTEAC AAERVVRPHQ LSPAGQAELL LRFPALEVPL RHPRPVLPPF DIAAEVAFTA 

       490        500        510        520        530        540 
RIHLACLRAL GQAIRAALQG GPRISQRLRY DFGPDQRAWL GEVTRRFPIL LENLMRAVEG 

       550        560        570        580        590        600 
TAPDAFFHTA YALAVLAHLG GRGGRGRRVV PLGDDLPARF ADSDGHYVFD YYSTSGDTLR 

       610        620        630        640        650        660 
LNNRPIAVAM DGDVSKREQS KCRFMEAVPS TAPRRVCEQY LPGESYAYLC LGFNRRLCGI 

       670        680        690        700 
VVFPGGFAFT INIAAYLSLS DPVARAAVLR FCRKVSSGNG RSR 

« Hide

References

[1]"The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1."
McGeoch D.J., Dalrymple M.A., Davison A.J., Dolan A., Frame M.C., McNab D., Perry L.J., Scott J.E., Taylor P.
J. Gen. Virol. 69:1531-1574(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Allosteric signaling and a nuclear exit strategy: binding of UL25/UL17 heterodimers to DNA-Filled HSV-1 capsids."
Trus B.L., Newcomb W.W., Cheng N., Cardone G., Marekov L., Homa F.L., Brown J.C., Steven A.C.
Mol. Cell 26:479-489(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: INTERACTION WITH UL25.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X14112 Genomic DNA. Translation: CAA32329.1.
PIRWMBET7. H30083.
RefSeqNP_044618.1. NC_001806.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-60386N.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2703388.

Phylogenomic databases

ProtClustDBPHA3359.

Family and domain databases

InterProIPR007640. Herpes_U64.
[Graphical view]
PfamPF04559. Herpes_UL17. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUL17_HHV11
AccessionPrimary (citable) accession number: P10201
Entry history
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: February 19, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families