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P10188

- NP04_HHV11

UniProt

P10188 - NP04_HHV11

Protein

Nuclear protein UL4

Gene

UL4

Organism
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Status
Reviewed - Annotation score: 1 out of 5- Protein inferred from homologyi
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    • History
      Entry version 47 (01 Oct 2014)
      Sequence version 1 (01 Jul 1989)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nuclear protein UL4
    Gene namesi
    ORF Names:UL4
    OrganismiHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
    Taxonomic identifieri10299 [NCBI]
    Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
    Virus hostiHomo sapiens (Human) [TaxID: 9606]
    ProteomesiUP000009294: Genome

    Subcellular locationi

    Host nucleus 1 Publication

    GO - Cellular componenti

    1. host cell nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Host nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 199199Nuclear protein UL4PRO_0000115898Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    IntActiP10188. 1 interaction.
    MINTiMINT-6732590.

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi156 – 1594Poly-Pro

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR004958. Herpes_UL4.
    [Graphical view]
    PfamiPF03277. Herpes_UL4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P10188-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNPQTTIAY SLCHARASLT SALPDAAQVV HVFEYGTRAI MVRGRERQDR    50
    LPRGGVVIQH TPIGLLVIID CRAEFCAYRF IGRDSNQKLE RGWDAHMYAY 100
    PFDSWVSSSR GESARSATAG ILTVVWTADT IYITATIYGS PPEETPGAAH 150
    GVGAAPPPPT TACPGTAEFL QPTADLLVEV LREIQLSPAL EYADKLLGS 199
    Length:199
    Mass (Da):21,517
    Last modified:July 1, 1989 - v1
    Checksum:iA50C0AB9FB9AA3F0
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti107 – 1071S → I in strain: Nonneuroinvasive mutant HF10.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X14112 Genomic DNA. Translation: CAA32340.1.
    DQ889502 Genomic DNA. Translation: ABI63466.1.
    M19119 Genomic DNA. Translation: AAA45820.1.
    PIRiD28133. WMBEX4.
    RefSeqiNP_044605.1. NC_001806.1.

    Genome annotation databases

    GeneIDi2703362.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X14112 Genomic DNA. Translation: CAA32340.1 .
    DQ889502 Genomic DNA. Translation: ABI63466.1 .
    M19119 Genomic DNA. Translation: AAA45820.1 .
    PIRi D28133. WMBEX4.
    RefSeqi NP_044605.1. NC_001806.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P10188. 1 interaction.
    MINTi MINT-6732590.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2703362.

    Family and domain databases

    InterProi IPR004958. Herpes_UL4.
    [Graphical view ]
    Pfami PF03277. Herpes_UL4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1."
      McGeoch D.J., Dalrymple M.A., Davison A.J., Dolan A., Frame M.C., McNab D., Perry L.J., Scott J.E., Taylor P.
      J. Gen. Virol. 69:1531-1574(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "Determination and analysis of the DNA sequence of highly attenuated herpes simplex virus type 1 mutant HF10, a potential oncolytic virus."
      Ushijima Y., Luo C., Goshima F., Yamauchi Y., Kimura H., Nishiyama Y.
      Microbes Infect. 9:142-149(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Nonneuroinvasive mutant HF10.
    3. "Structures of herpes simplex virus type 1 genes required for replication of virus DNA."
      McGeoch D.J., Dalrymple M.A., Dolan A., McNab D., Perry L.J., Taylor P., Challberg M.D.
      J. Virol. 62:444-453(1988) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-17.
    4. "Identification of the UL4 protein of herpes simplex virus type 1."
      Eide T., Marsden H.S., Leib D.A., Cunningham C., Davison A.J., Langeland N., Haarr L.
      J. Gen. Virol. 79:3033-3038(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION, SUBCELLULAR LOCATION.
      Strain: 17 syn+.

    Entry informationi

    Entry nameiNP04_HHV11
    AccessioniPrimary (citable) accession number: P10188
    Secondary accession number(s): Q09IC9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 1, 1989
    Last sequence update: July 1, 1989
    Last modified: October 1, 2014
    This is version 47 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3