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P10188

- NP04_HHV11

UniProt

P10188 - NP04_HHV11

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Protein
Nuclear protein UL4
Gene
UL4
Organism
Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Names & Taxonomyi

Protein namesi
Recommended name:
Nuclear protein UL4
Gene namesi
ORF Names:UL4
OrganismiHuman herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus 1)
Taxonomic identifieri10299 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeAlphaherpesvirinaeSimplexvirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
ProteomesiUP000009294: Genome

Subcellular locationi

Host nucleus 1 Publication

GO - Cellular componenti

  1. host cell nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 199199Nuclear protein UL4
PRO_0000115898Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiP10188. 1 interaction.
MINTiMINT-6732590.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi156 – 1594Poly-Pro

Sequence similaritiesi

Family and domain databases

InterProiIPR004958. Herpes_UL4.
[Graphical view]
PfamiPF03277. Herpes_UL4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P10188-1 [UniParc]FASTAAdd to Basket

« Hide

MSNPQTTIAY SLCHARASLT SALPDAAQVV HVFEYGTRAI MVRGRERQDR    50
LPRGGVVIQH TPIGLLVIID CRAEFCAYRF IGRDSNQKLE RGWDAHMYAY 100
PFDSWVSSSR GESARSATAG ILTVVWTADT IYITATIYGS PPEETPGAAH 150
GVGAAPPPPT TACPGTAEFL QPTADLLVEV LREIQLSPAL EYADKLLGS 199
Length:199
Mass (Da):21,517
Last modified:July 1, 1989 - v1
Checksum:iA50C0AB9FB9AA3F0
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti107 – 1071S → I in strain: Nonneuroinvasive mutant HF10.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14112 Genomic DNA. Translation: CAA32340.1.
DQ889502 Genomic DNA. Translation: ABI63466.1.
M19119 Genomic DNA. Translation: AAA45820.1.
PIRiD28133. WMBEX4.
RefSeqiNP_044605.1. NC_001806.1.

Genome annotation databases

GeneIDi2703362.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14112 Genomic DNA. Translation: CAA32340.1 .
DQ889502 Genomic DNA. Translation: ABI63466.1 .
M19119 Genomic DNA. Translation: AAA45820.1 .
PIRi D28133. WMBEX4.
RefSeqi NP_044605.1. NC_001806.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P10188. 1 interaction.
MINTi MINT-6732590.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2703362.

Family and domain databases

InterProi IPR004958. Herpes_UL4.
[Graphical view ]
Pfami PF03277. Herpes_UL4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1."
    McGeoch D.J., Dalrymple M.A., Davison A.J., Dolan A., Frame M.C., McNab D., Perry L.J., Scott J.E., Taylor P.
    J. Gen. Virol. 69:1531-1574(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "Determination and analysis of the DNA sequence of highly attenuated herpes simplex virus type 1 mutant HF10, a potential oncolytic virus."
    Ushijima Y., Luo C., Goshima F., Yamauchi Y., Kimura H., Nishiyama Y.
    Microbes Infect. 9:142-149(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Nonneuroinvasive mutant HF10.
  3. "Structures of herpes simplex virus type 1 genes required for replication of virus DNA."
    McGeoch D.J., Dalrymple M.A., Dolan A., McNab D., Perry L.J., Taylor P., Challberg M.D.
    J. Virol. 62:444-453(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-17.
  4. "Identification of the UL4 protein of herpes simplex virus type 1."
    Eide T., Marsden H.S., Leib D.A., Cunningham C., Davison A.J., Langeland N., Haarr L.
    J. Gen. Virol. 79:3033-3038(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION, SUBCELLULAR LOCATION.
    Strain: 17 syn+.

Entry informationi

Entry nameiNP04_HHV11
AccessioniPrimary (citable) accession number: P10188
Secondary accession number(s): Q09IC9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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