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Protein

Cytochrome c oxidase subunit 7

Gene

COX7

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 639 molecules/cell in log phase SD medium.1 Publication

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

  • mitochondrial electron transport, cytochrome c to oxygen Source: SGD

Keywordsi

Molecular functionOxidoreductase

Enzyme and pathway databases

BioCyciMetaCyc:YMR256C-MONOMER
YEAST:YMR256C-MONOMER

Protein family/group databases

TCDBi3.D.4.8.1 the proton-translocating cytochrome oxidase (cox) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 7 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide VII
Gene namesi
Name:COX7
Ordered Locus Names:YMR256C
ORF Names:YM9920.10C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR256C
SGDiS000004869 COX7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei31 – 51HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001839072 – 60Cytochrome c oxidase subunit 7Add BLAST59

Proteomic databases

PaxDbiP10174
PRIDEiP10174

Interactioni

Subunit structurei

Cytochrome c oxidase is composed of 11 subunits: one copy each of COX1, COX2, COX3, COX4, COX5A or COX5B, COX6, COX7, COX9, COX12, COX13 and two copies of COX8.

Protein-protein interaction databases

BioGridi35434, 313 interactors
IntActiP10174, 6 interactors
MINTiP10174
STRINGi4932.YMR256C

Structurei

3D structure databases

ProteinModelPortaliP10174
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000248810
InParanoidiP10174
KOiK02269
OMAiMNPQRII
OrthoDBiEOG092C5ZBW

Family and domain databases

InterProiView protein in InterPro
IPR014367 Cox7
PIRSFiPIRSF000282 COX7, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P10174-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANKVIQLQK IFQSSTKPLW WRHPRSALYL YPFYAIFAVA VVTPLLYIPN
60
AIRGIKAKKA
Length:60
Mass (Da):6,932
Last modified:January 23, 2007 - v3
Checksum:i5798C96AF8134D6D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X51506 Genomic DNA Translation: CAA35871.1
M31620 Genomic DNA Translation: AAA34550.1
Z48639 Genomic DNA Translation: CAA88583.1
AY558129 Genomic DNA Translation: AAS56455.1
BK006946 Genomic DNA Translation: DAA10156.1
PIRiS22248 OBBY7
RefSeqiNP_013983.1, NM_001182763.1

Genome annotation databases

EnsemblFungiiYMR256C; YMR256C; YMR256C
GeneIDi855298
KEGGisce:YMR256C

Similar proteinsi

Entry informationi

Entry nameiCOX7_YEAST
AccessioniPrimary (citable) accession number: P10174
Secondary accession number(s): D6W082
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: January 23, 2007
Last modified: May 23, 2018
This is version 145 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

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