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Protein

Proline-rich proteoglycan 2

Gene

Prpg2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Proline-rich proteoglycan 2
Alternative name(s):
Acidic proline-rich protein PRP18
Gene namesi
Name:Prpg2
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi628797. Prpg2.

Subcellular locationi

  • Secreted 1 Publication

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_000002213217 – 295Proline-rich proteoglycan 2Add BLAST279

Post-translational modificationi

Contains glycosaminoglycans of chondroitin-sulfate and heparan types.

Proteomic databases

PaxDbiP10165.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000013943.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi46 – 279Pro-richAdd BLAST234

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

KOiK13911.

Family and domain databases

InterProiIPR026086. Pro-rich.
[Graphical view]
PANTHERiPTHR23203. PTHR23203. 1 hit.
PfamiPF15240. Pro-rich. 1 hit.
[Graphical view]
SMARTiSM01412. Pro-rich. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P10165-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVVLLTAAL LVLSSAQGVD EEVVYEDSSQ QLELEQQSQG HGQHHPKPPP
60 70 80 90 100
GGLPPRPPAS DENGDGDDND DGDDDGSGDD VNRPERPPQH GGNHHHPHHP
110 120 130 140 150
PPAAGPQRPP QPGSPQGPPP PGGPQQRPPQ GPPPQGGPQR PPQPGSPQGP
160 170 180 190 200
PPPGGPQQRP PQGPPPQGGP QRPPQPGSPQ GPPPPGGPQQ RAPQGPPPQG
210 220 230 240 250
GPQRPPQPGS PQGPPPPGGP QQRPPQGPPP QGGPQRPPQP GSPQGPPPPG
260 270 280 290
GPQQRPPQGP PPQGGPQRPP QPGNPQGPPQ QGGQQQSSFL WSFSA
Length:295
Mass (Da):30,026
Last modified:July 10, 2007 - v2
Checksum:iEEA44BD8B38E1B9F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti17Q → H in AAA41956 (PubMed:3840480).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L17318 mRNA. Translation: AAA03074.1.
M11899 mRNA. Translation: AAA41956.1.
PIRiB48013.
RefSeqiNP_742062.1. NM_172065.2.
UniGeneiRn.29950.

Genome annotation databases

GeneIDi257651.
KEGGirno:257651.
UCSCiRGD:628797. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L17318 mRNA. Translation: AAA03074.1.
M11899 mRNA. Translation: AAA41956.1.
PIRiB48013.
RefSeqiNP_742062.1. NM_172065.2.
UniGeneiRn.29950.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000013943.

Proteomic databases

PaxDbiP10165.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi257651.
KEGGirno:257651.
UCSCiRGD:628797. rat.

Organism-specific databases

CTDi381832.
RGDi628797. Prpg2.

Phylogenomic databases

KOiK13911.

Miscellaneous databases

PROiP10165.

Family and domain databases

InterProiIPR026086. Pro-rich.
[Graphical view]
PANTHERiPTHR23203. PTHR23203. 1 hit.
PfamiPF15240. Pro-rich. 1 hit.
[Graphical view]
SMARTiSM01412. Pro-rich. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPRPG2_RAT
AccessioniPrimary (citable) accession number: P10165
Secondary accession number(s): Q07611
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 10, 2007
Last modified: June 8, 2016
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.