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Protein

Protein C-ets-2

Gene

ETS2

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Probable transcription factor.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi373 – 453ETSPROSITE-ProRule annotationAdd BLAST81

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

ReactomeiR-GGA-2559585. Oncogene Induced Senescence.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein C-ets-2
Gene namesi
Name:ETS2
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Keywords - Diseasei

Proto-oncogene

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002040761 – 479Protein C-ets-2Add BLAST479

Proteomic databases

PaxDbiP10157.
PRIDEiP10157.

Expressioni

Gene expression databases

BgeeiENSGALG00000016059.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000025826.

Structurei

3D structure databases

ProteinModelPortaliP10157.
SMRiP10157.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini88 – 173PNTPROSITE-ProRule annotationAdd BLAST86

Sequence similaritiesi

Belongs to the ETS family.Curated

Phylogenomic databases

eggNOGiKOG3806. Eukaryota.
ENOG410Z0ZF. LUCA.
GeneTreeiENSGT00760000118907.
HOGENOMiHOG000285953.
HOVERGENiHBG003088.
InParanoidiP10157.
KOiK21932.
OMAiFGMNGQV.
OrthoDBiEOG091G0HJF.
PhylomeDBiP10157.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000418. Ets_dom.
IPR003118. Pointed_dom.
IPR013761. SAM/pointed.
IPR016311. Transform_prot_C-ets.
IPR027276. Transform_prot_C-ets-2.
IPR036388. WH-like_DNA-bd_sf.
IPR036390. WH_DNA-bd_sf.
PfamiView protein in Pfam
PF00178. Ets. 1 hit.
PF02198. SAM_PNT. 1 hit.
PIRSFiPIRSF501032. C-ets-2. 1 hit.
PIRSF001698. Transforming_factor_C-ets. 1 hit.
PRINTSiPR00454. ETSDOMAIN.
SMARTiView protein in SMART
SM00413. ETS. 1 hit.
SM00251. SAM_PNT. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF47769. SSF47769. 1 hit.
PROSITEiView protein in PROSITE
PS00345. ETS_DOMAIN_1. 1 hit.
PS00346. ETS_DOMAIN_2. 1 hit.
PS50061. ETS_DOMAIN_3. 1 hit.
PS51433. PNT. 1 hit.

Sequencei

Sequence statusi: Complete.

P10157-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEFAIRNMD QVAPVSNMYR GMLKRQPAFD TFDSSNSLFA GYFLSLNEDQ
60 70 80 90 100
TLQEVPTGFD STSYESNNCE LPLLTPCSKA VMSQALKDTF SGFTKEQCRL
110 120 130 140 150
GIPNNPWLWT EQHVCQWLAW ATNEFSLANV NIHQFLMSGQ DLCNLGKERF
160 170 180 190 200
LELAPDYVGD ILWEHLEQMI KDSQEKTQDQ YVESSHLTSV PHWVNNNSLT
210 220 230 240 250
VNVDQTPYGI QMPGYPKALS YPKPNLLSDI CQTSTGPNLL SPEQDFSLFP
260 270 280 290 300
KTQVDAVSVN YCTVNQDFTR SNLNLLIDNS GKLREHESSE SGAESYESSD
310 320 330 340 350
SMLQSWNSQS SLVDLQRVPS YESFEDDCSQ SLCMSKPTMS FKDYIQDRSD
360 370 380 390 400
PVEQGKPVIP AAILAGFTGS GPIQLWQFLL ELLTDKSCQS FISWTGDGWE
410 420 430 440 450
FKLADPDEVA RRWGRRKNKP KMNYEKLSRG LRYYYDKNII HKTSGKRYVY
460 470
RFVCDLQNLL GYTAEELHAM LGVQPDTED
Length:479
Mass (Da):54,540
Last modified:July 1, 1989 - v1
Checksum:i91BCD5206972E867
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X07202 mRNA. Translation: CAA30178.1.
PIRiS00386. TVCHE2.
RefSeqiNP_990643.1. NM_205312.1.
UniGeneiGga.4768.

Genome annotation databases

EnsembliENSGALT00000025873; ENSGALP00000025826; ENSGALG00000016059.
GeneIDi396250.
KEGGigga:396250.

Similar proteinsi

Entry informationi

Entry nameiETS2_CHICK
AccessioniPrimary (citable) accession number: P10157
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 1, 1989
Last sequence update: July 1, 1989
Last modified: October 25, 2017
This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families